Sezaryen Sonrası Farklı Yöntemlerin Arasında Postoperatif Analjezik Etkinliğin Karşılaştırılması
Amaç: Bu araştırmada, sezaryen yapılan olgularda, genel anesteziye eklenen transversus abdominis plan bloğu (TAP) ile epidural anestezi ve spinal anestezinin postoperatif analjezik etkileri karşılaştırıldı. Sezaryen ameliyatı sonrası TAP bloğun etkinliği belirlenmeye çalışıldı. Yöntem: Etik Kurul (25.03.2015/142) izni alındıktan sonra, elektif şartlarda sezaryen planlanan olgular, spinal anestezi, epidural anestezi ve genel anestezi olmak üzere 3 gruba ayrıldı. Bu araştırma, genel anesteziye eklenen TAP yapılan 30 olgu (Grup T) ile epidural anestezi yapılan 32 olgu (Grup E) ve spinal anestezi yapılan 30 olgu (Grup S) olmak üzere toplam 92 olgudan oluşmaktadır. Tüm olgulara ameliyat bitiminde diklofenak sodyum 75 m IM uygulandı.Olguların postoperatif ağrılarının ne zaman başladığı ve Görsel Analog Skala (GAS)’ya göre hangi şiddette olduğu ve olguların ek analjezik gereksinimleri ile postoperatif 0. saat, 1. saat, 4. saat 6. saat ve 12. saatteki kalp atım hızı, kan basıncı, periferik O2 saturasyonu, solunum sayıları ile görülen yan etkiler kaydedildi. Postoperatif dönemde olguların ek analjezik gereksinimleri olduğunda 50 mg tramadol IV uygulandı. Bulgular: Postoperatif analjezik gereksinimi açısından gruplar arasında anlamlı bir fark bulunmadı (Tablo II). Grup T’de de Grup S’ye göre daha az tramadol tüketimi gerçekleşmiştir (p
Comparison of Postoperative Analgesic ID Efficacy of Different Methods After Cesarean-Section
Objective: In this research study,we compared postoperative analgesic effects of general anesthesiafollowed with transversus abdominis plane block (TAPB), epidural or spinal anesthesia andwe aimed to figure out the efficacy of TAPB for the postoperative pain.Method: After approval of the ethics committee (date: 03.25.2015; decision no: 142) for thestudy was obtained, the study population scheduled for elective cesarean operations was dividedin three subgroups as spinal, epidural and general anesthesia. Group T consisted of 30 cases thatunderwent general anesthesia and TAP; Group E consisted of 32 cases that underwent epiduralanesthesia; and Group S consisted of 30 cases that underwent spinal anesthesia. All casesreceived 75 mg IM diclophenac sodium after the operation. Data about the postoperative pain(the onset time of the pain, and the severity of the pain evaluated with VAS (Visual Analog Scale)and the need for adjuvant analgesics) were recorded. In addition, heart rate, blood pressure,peripheric oxygen saturation, respiration rates at postoperative 0., 1., 4., 6. and 12. hours andside effects seen were recorded. If the patient needed any additional postoperative analgesics,50 mg tramadol was injected intravenously.Results: There was no significant difference between the groups regarding postoperative analgesianeed (Table II). The need for postoperative tramadol was minimum for patients in Group E andmaximum for patients in Group S (p
___
- 1. Barber EL, Lundsberg LS, Belanger K, Pettker CM, Funai EF, Illuzzi JL. Indications contributing to the increasing cesarean delivery rate. Obstet Gynecol. 2011;118:29-38. https://doi.org/10.1097/AOG.0b013e31821e5f65
- 2. Benyamin R, Trescot AM, Datta S et al. Opioid complications and side effects. Pain Physician. 2008;11:S105- 20.
- 3. Dalal PG, Bosak J, Berlin C. Safety of the breast-feeding infant after maternal anesthesia. Paediatr Anaesth. 2014;24:359-71. https://doi.org/10.1111/pan.12331
- 4. Horlocker TT. Complications of spinal and epidural anesthesia. Anesthesiol Clin North America. 2000;18:461-85. https://doi.org/10.1016/S0889-8537(05)70172-3
- 5. Lavoie A, Toledo P. Multimodal postcesarean delivery analgesia. Clin Perinatol. 2013;40:443-55. https://doi.org/10.1016/j.clp.2013.05.008
- 6. Brogi E, Kazan R, Cyr S, Giunta F, Hemmerling TM. Transversus abdominal plane block for postoperative analgesia: a systematic review and meta-analysis of randomized-controlled trials. Can J Anaesth. 2016;63:1184-96. https://doi.org/10.1007/s12630-016-0679-x
- 7. Champaneria R, Shah L, Wilson MJ, Daniels JP. Clinical effectiveness of transversus abdominis plane (TAP) blocks for pain relief after caesarean section: a metaanalysis. Int J Obstet Anesth. 2016;28:45-60. https://doi.org/10.1016/j.ijoa.2016.07.009
- 8. Christmas T, Bamber J, Patient C. Maternal satisfaction with analgesia following hospital discharge after caesarean section. Int J Obstet Anesth. 2015;24:85-6. https://doi.org/10.1016/j.ijoa.2014.07.008
- 9. Anwari JS, Butt A, Alkhunein S. PCA after subarachnoid block for cesarean section. Middle East J Anaesthesiol. 2004;17:913-26.
- 10. Niesen AD, Jacob AK. Combined spinal-epidural versus epidural analgesia for labor and delivery. Clin Perinatol. 2013;40:373-84. https://doi.org/10.1016/j.clp.2013.05.010
- 11. Ripollés J, Mezquita SM, Abad A, Calvo J. Analgesic efficacy of the ultrasound-guided blockade of the transversus abdominis plane - a systematic review. Braz J Anesthesiol. 2015;65:255-80. https://doi.org/10.1016/j.bjane.2013.10.016
- 12. Fusco P, Scimia P, Paladini G et al. Transversus abdominis plane block for analgesia after Cesarean delivery. A systematic review. Minerva Anestesiol. 2015;81:195-204.
- 13. Lee AJ, Palte HD, Chehade JM, Arheart KL, Ranasinghe JS, Penning DH. Ultrasound-guided bilateral transversus abdominis plane blocks in conjunction with intrathecal morphine for postcesarean analgesia. J Clin Anesth. 2013;25:475-82. https://doi.org/10.1016/j.jclinane.2013.05.004
- 14. Tan TT, Teoh WH, Woo DC, Ocampo CE, Shah MK, Sia AT. A randomised trial of the analgesic efficacy of ultrasound-guided transversus abdominis plane block after caesarean delivery under general anaesthesia. Eur J Anaesthesiol. 2012;29:88-94. https://doi.org/10.1097/EJA.0b013e32834f015f
- 15. Onishi Y, Kato R, Okutomi T, Tabata K, Amano K, Unno N. Transversus abdominis plane block provides postoperative analgesic effects after cesarean section: additional analgesia to epidural morphine alone. J Obstet Gynaecol Res. 2013;39:1397-405. https://doi.org/10.1111/jog.12074
- 16. Buluc H, Ar AY, Turan G, Karadogan F, Sargin MA, Akgun N. The efficacy of transversus abdominis plane block for post-operative analgesia after the cesarean section performed under general anesthesia. North Clin Istanb. 2019;6:368-73. https://doi.org/10.14744/nci.2018.97059
- 17. Jadon A, Jain P, Chakraborty S, Motaka M, Parida SS, Sinha N, Agrawal A, Pati AK. Role of ultrasound guided transversus abdominis plane block as a component of multimodal analgesic regimen for lower segment caesarean section: a randomized double blind clinical study. BMC Anesthesiol. 2018;18(1):53. https://doi.org/10.1186/s12871-018-0512-x
- 18. Loane H, Preston R, Douglas MJ, Massey S, Papsdorf M, Tyler J. A randomized controlled trial comparing intrathecal morphine with transversus abdominis plane block for post-cesarean delivery analgesia. Int J Obstet Anesth. 2012;21:112-8. https://doi.org/10.1016/j.ijoa.2012.02.005
- 19. Kanazi GE, Aouad MT, Abdallah FW et al. The analgesic efficacy of subarachnoid morphine in comparison with ultrasound-guided transversus abdominis plane block after cesar ean delivery: a randomized controlled trial. Anesth Analg. 2010;111:475-81. https://doi.org/10.1213/ANE.0b013e3181e30b9f
- 20. Eslamian L, Jalili Z, Jamal A, Marsoosi V, Movafegh A. Transversus abdominis plane block reduces postoperative pain intensity and analgesic consumption in elective cesarean delivery under general anesthesia. J Anesth. 2012;26:334-8. Anesth Analg. 2010;111:475-81. https://doi.org/10.1007/s00540-012-1336-3