Dilek YÖRÜKOĞLU, Alev AYDOS, Burhanettin USTA, Feyhan ÖKTEN

Propofol enjeksiyon ağrısının önlenmesinde alfentanil, ketamin, ketorolak ve difenhidraminin karşılaştırılması

Bu randomize çalışmada 100 hasta propofol enjeksiyon ağrısı bakımından değerlendirildi. Hastalara propofol enjeksiyonundan önce el sırtındaki bir venden salin (kontrol grubu), alfentanil, ketamin, ketorolak ya da difenhidramin verildi. Propofol enjeksiyonu sırasında ağrı insidansı kontrol grubunda diğer gruplara göre anlamlı olarak yüksekti. Diğer gruplar arasında anlamlı fark olmamasına karşın klinik olarak ketamin ve difenhidraminin daha etkili olduğu görüldü.

Anahtar Kelimeler:

Anti-enflamatuvar ajanlar, steroid olmayan, Ağrı, Ağrı ölçümü, Alfentanil, Ketamin, Difenhidramin, Propofol, Enjeksiyonlar

Comparison of alfentanil, ketamine, ketorolac and diphenhidramine for prevention of propofol induced injection

Pain on injection of propofol was assessed in a randomised study of 100 patients. The patients received either saline (control group), alfentanil, ketamin, ketorolac or diphenhidramine before injection of propofol via a vein in the dorsum of the hand. The incidence of pain on injection of propofol in the control group was significantly higher than the other groups. Although there was no difference among alfentanil, ketamine, ketorolac and diphenhidramine groups in preventing propofol induced pain, ketamine and diphenhidramine seemed to be clinically more effective than others.

Keywords:

Anti-Inflammatory Agents, Non-Steroidal, Pain, Pain Measurement, Alfentanil, Ketamine, Diphenhydramine, Propofol, Injections,

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