Canan BALCI, Remziye Gül SIVACI, Özlem SAKA, Gökhan AKBULUT

Desfluran ve sevofluranın derlenme sürelerinin bispektral indeks değerleri ile karşılaştırılması

Amaç: Bu çalışma elektifalt batın cerrahisi geçirecek olgularda desfluran ve sevofluranın derlenme sürelerinin ve bu sürelerdeki Bispektral İndeks (BİS) değerlerinin karşılaştırılmasını amaçlamaktadır. Yöntem: Genel anestezi altında elektif batın cerrahisi planlanan ASA I-II grubunda 60 olgu çalışmaya dahil edildi. Olgularımız rastgele seçimle iki gruba ayrıldı. Anestezi indüksiyonu her iki grupta intravenöz 2 mg kg' propofol ile yapıldı. Anestezi idamesi ise BİS değerleri 50-60 olacak şekilde; Grup S'de (n=30) sevofluran (% 0.6-1.75), % 50 hava ve % 50 02 karışımı ile yapıldı. Grup D'da ise (n=30) desfluran (% 2-6), % 50 hava ve % 50 02 karışımı ile sağlandı. Tüm olgularda BİS, ortalama arter basıncı (OAB), kalp atım hızı (KAH) ve periferik oksijen satürasyonu (SpO2) indüksiyon öncesi, endotrakeal entübasyonu takiben 1, 5, 10, 15. ve operasyon bitimine kadar 5 dakika aralıklarla kaydedildi. Anestezi süresince anestezik ajan konsantrasyonları BİS 50-60 olacak şekilde ayarlandı. Anestezinin sonlanmasını takiben desfluran ve sevofluranın spontan solunum süresi (SSS), spontan göz açma süresi (SGAS), ekstübasyon süresi (ES), bilinç süresi (yer ve zaman oryantasyonu) (BS), modifiye Aldrete skoru >9 olma süresi (MAS), derlenme ünitesinden çıkarılma süresi (DÜÇS) belirlendi. Çalışmamızda aynı zamanda spontan solunum süresi BIS (SSSB), spontan göz açma süresi BİS (SGASB), ekstübasyon öncesi BİS (EÖB), ekstübasyon sonrası BİS (ESB), bilinç süresi BİS (BSB), modifiye Aldrete skoru >9 olma süresi BİS (MASB) ve derlenme ünitesi çıkış BİS (DÜÇSB) değerleri tespit edildi. Bulgular: Çalışma sonunda, desfluran grubunda sevofluran grubuna oranla SSS, SGAS, ES, BS, MAS, DÜÇS değerleri anlamlı olarak kısa bulundu (p

Anahtar Kelimeler:

Anestezikler, inhalasyon, Anesteziden uyanma dönemi, Cerrahi işlemler, operatif

Comparison of desflurane and sevoflurane recovery duration with BIS values

Objective: To compare the recovery time and the Bispectral Index (BIS) values of desflurane and sevoflurane in patients scheduled to undergo elective lower abdominal surgery. Method: Sixty ASA I-II patients scheduled for elective abdominal surgery under general anesthesia were included the study. The subjects were randomly divided into two groups. In both groups, anesthesia inductions were performed with TV propofol per 2 mg kg'1 and the BIS values were kept between 50-60. In group S (n=30), maintenance was provided with a mixture of sevoflurane (0.6-1.75 %), 50 % airlO2. In group D (n=30), maintenance was provided with desflurane (2-6 %), 50 % air and 50 % 02. BIS, mean arterial pressure, pulse rate and peripherial oxygen saturation were recorded before induction in all cases, in 1st, 5th, 10th, 15th minutes after endotracheal entubation and with 5 minute intervals during the rest of the operation. When anesthesia was terminated, spontaneous eye opening time (SEOT), spontaneous respiration time (SRT), extubation time (ET), consciousness time (location and time orientation) (CT), modified Aldrete score >9 time (MAST), postanaesthesia care unit discharge time (DTPACU) and BIS values were recorded. Results: At the end of the study, SEOT, SRT, ET, CT, MAST, DTPACU values for the desflurane group were found to be statistically significant compared to sevoflurane (p<0.05). Conclusion: Desflurane has a more rapid recovery time when compared with sevoflurane but no difference was found between the two agents with regard to the BIS values. Desflurane may be used safely in patients who are scheduled to undergo lower abdominal surgery under general anesthesia.

Keywords:

Anesthetics, Inhalation, Anesthesia Recovery Period, Surgical Procedures, Operative,

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