Gurhan BAS, Kerem TOLAN, Tunc EREN, Orhan ALİMOGLU, Tamador SHAMAİLEH, Ali KİLİC

The Incidence of Pericolonic Tumor Deposits in Colorectal Cancer

Amaç: Güncel olarak, hastalar arasında prognostik farklılıkları değerlendirmek için Amerikan Kanser Ortak Komitesi (American Joint Committee on Cancer--AJCC) tarafından geliştirilen Tümör-Nodül-Metastaz (TNM) Evreleme Sistemi kullanılmaktadır. Amacımız kolorektal kanser nedeniyle ameliyat olan hastalarda perikolonik tümör depozitlerinin görülme sıklığını değerlendirmek ve tümör evreleri ile ilişkisini göstermektir. Gereç ve Yöntemler: Kolorektal kanser için cerrahi rezeksiyon yapılan toplam 190 hastanın patolojik bulguları retrospektif olarak değerlendirildi. Evreleme, Amerikan Kanser Ortak Komitesi kanser evreleme kılavuzunun yedinci edisyonuna uygun olarak gerçekleştirildi. Bulgular: 190 kolorektal kanserli hastanın 30'unda (%15,8) perikolonik tümör depoziti saptandı. Patoloji sonuçlarına göre hastaların %66,6'sı T3, %46,6'sı ise N1c evresinde idi. Ayrıca %56,6 olgu Evre IIIB olarak rapor edildi.Tartışma ve Sonuç: Lenf nodu tutulumunun diğer kanıtları yok ise perikolonik tümör depozitlerinin varlığı hastalığın Evre II'den Evre III'e yeniden sınıflandırılmasını sağlar. Evre III'teki hastalarda adjuvan tedavi gerekmesi nedeniyle tümör depozitlerinin varlığından dolayı ortaya çıkan üst evreye kayma önemlidir

Kolorektal Kanserlerde Perikolonik Tümör Depozitlerinin Sıklığı

Aim: Currently, the primary method for assessing the prognostic differences among patients is the tumor-node-metastasis (TNM) staging system developed by the American Joint Committee on Cancer (AJCC). Our aim was to evaluate the incidence of the presence of pericolonic tumor deposits in patients operated on for colorectal cancer, and to demonstrate its relation with tumor stages. Materials and Methods: The pathological findings of a total number of 190 patients who underwent surgical resections for colorectal cancer were evaluated retrospectively. Staging was carried out according to the 7th edition of the AJCC staging manual. Results: Among all 190 colorectal cancer patients, a total of 30 (15.8%) patients were detected to harbor pericolonic tumor deposits. In the final pathology reports, 66.6% of the patients were reported as T3, and 46.6% were reported as N1c. Thus, 56.6% of the patients were reported as Stage IIIB. Discussion and Conclusion: In the absence of other evidence of lymph node involvement, the presence of pericolonic tumor deposits results in the reclassification of the disease from Stage II to Stage III. The fact that Stage III disease necessitates adjuvant treatment puts forth an emphasis on the importance of upstaging due to the presence of tumor deposits

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