Fatih Doğan, Seyfullah Oktay Arslan, Fidan Pesen Özdoğan, Kemal Gökhan Ulusoy, Enis Macit, Saliha Ayşenur Cam, Fatma Uysal

Galaktagog Etki İçin Kullanılan Bitkisel Çayların Farmakolojik Bileşenlerinin Gaz Kromatografisi/ Kütle Spektrometrisi ile Analizi

Amaç: Bu çalışmada, anne sütü üretimini artırmak için kullanılan bir dizi bitki ve bitkisel çayın bileşenlerinin gaz kromatografisi/kütle spektrometrisi (GK/KS) ile analizi amaçlanmıştır. Gereç ve Yöntemler: Metanol ekstreleri maserasyon metoduyla rotatif buharlaştırıcı kullanılarak hazırlanmıştır. Uçucu yağların elde edilmesinde ise Clevenger yöntemi kullanılmıştır. Bulgular: Foeniculum vulgare, Pimpinella anisum, Trigonella foenum graceum, Urtica dioica ve Nigella sativa tıbbi bitkilerinin ve bunların piyasadaki çaylarının uçucu yağlarının ve metanol ekstrelerinin GK/KS analizleri yüksek hassasiyetle gerçekleştirilmiştir. Tespit edilen kimyasal bileşenler tablolarda ayrıntılı olarak belirtilmiştir. Tartışma ve Sonuç: Çalışmamızda tanımlanan bileşenlerin olası farmakolojik etkileri literatür ışığında yorumlanmıştır. Bulgularımız, gelecekte anne sütünü artırmak ya da başka tıbbi amaçlar için kullanılabilecek bu bitki ve bitkisel çayların aktif farmakolojik bileşenleri üzerine yapılacak araştırmalar için yol gösterici niteliktedir.

An Analysis of the Pharmacological Components of Herbal Teas Used for Galactagogue Effects by Gas Chromatography/Mass Spectrometry

Aim: This study aimed to analyze the phytochemical components of a number of herbs andherbal teas used to improve breast milk production by gas chromatography/mass spectrometry (GC/MS).Materials and Methods: The methanolic extracts were prepared by the maceration method using a rotary evaporator. The essential oils were obtained by the Clevenger method.Results: The GC/MS analyses of the essential oils and methanol extracts of the medicinal herbsFoeniculum vulgare, Pimpinella anisum, Trigonella foenum graceum, Urtica dioica, and Nigellasativa, and their teas on the market were performed with high sensitivity. The chemical components identified were presented in detailed tables.Discussion and Conclusions: In our study possible pharmacological effects of the componentsidentified were discussed in light of the literature. Our findings are guiding for further researchon the pharmacologically active components of these herbs and herbal teas that may be usedfor breast milk enhancement or other medical purposes in the future.

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