Duran YILDIZ, Ufuk ÇAKIR, Ali Ulaş TUĞCU, Cüneyt TAYMAN

PREMATÜRELERDE KAN GRUPLARININ BRONKOPULMONER DİSPLAZİYE ETKİSİ

Amaç: Özellikle prematüre bebeklerde ciddi solunumsal morbiditelere neden olan bronkopulmoner displazi ile kan grubu arasındaki ilişkisi bilinmemektedir. Çalışmamızda prematüre bebeklerde bronkopulmoner displazi ile kan grubunun ilişkisinin değerlendirilmesi amaçlanmıştır. Yöntem: Çalışmamızda ünitemizde yatan ≤32 gebelik haftasında doğan prematüre bebekler retrospektif değerlendirildi. Tüm kan grupları bronkopulmoner displazi, demografik ve klinik özellikler açısından birbirleri ile karşılaştırıldı. Bulgular: Çalışmaya O kan grubunda 110 (%31,1), A kan grubunda 155 (%43,8), B kan grubunda 63 (%17,8) ve AB kan grubunda 26 (%7,3) olmak üzere toplam 354 prematüre bebek dahil edildi. Kan grupları arasında bronkopulmoner displazi, demografik ve klinik özellikler açısından istatistiksel anlamlı fark saptanmadı (p>0,05). Sonuç: Çalışmamızda kan grubu ve bronkopulmoner displazi ilişkisi gösterilememiştir. Prematüre bebeklerde bronkopulmoner displazi ile kan grubu arasında ilişki olup olmadığı halen bilinmemektedir.

Anahtar Kelimeler:

bronkopulmoner displazi, kan grubu, prematüre

THE EFFECT OF BLOOD GROUPS ON BRONCHOPULMONARY DYSPLASIA IN PREMATURE

Objective: It is not known that if any relationship between bronchopulmonary dyplasia which causes severe respiratory distress and blood group types. We aimed to identify the relationship between bronchopulmonary dyplasia and blood group types. Methods: We retrospectively evaluated and compared bronchopulmonary dyplasia, demographic data and clinical features of preterm newborns, born before 32th gestational age. All blood groups were compared with each other in terms of bronchopulmonary dyplasia, demographic and clinical features. Results: A total of 354 preterm newborns (110 (31.1%) with 0 blood group type, 155 (43.8%) with A blood group type, 63 (17.8%) with B blood group type and 26 (7.3%) with AB blood group type) were enrolled into the study. No statistically significancy is found among blood groups in bronchopulmonary dyplasia, demographic data and clinical features (p>0.05). Conclusion: We could not show any relationship between bronchopulmonary dyplasia and blood group types. Any possible relationship between bronchopulmonary dyplasia and blood group types, is still not known.

Keywords:

blood group, bronchopulmonary dysplasia, premature,

PDF

___

Referans1. Northway WH Jr, Rosan RC, Porter DY. Pulmonary disease following respirator therapy of hyaline-membrane disease. Bronchopulmonary dysplasia. N Engl J Med. 1967;276(7):357-368. doi: 10.1056/NEJM196702162760701.
Referans2. Arsan S, Korkmaz A, Oğuz S. Turkish Neonatal Society guideline on prevention and management of bronchopulmonary dysplasia. Turk Pediatri Ars. 2018;53(Suppl 1):S138-S150. doi: 10.5152/TurkPediatriArs.2018.01814.
Referans3. Mammel D, Kemp J. Prematurity, the diagnosis of bronchopulmonary dysplasia, and maturation of ventilatory control. Pediatr Pulmonol. 2021;56(11):3533-3545. doi: 10.1002/ppul.25519.
Referans4. Mroczek B, Sitko Z, Sujewicz A, Wolińska W, Karpeta-Pawlak I, Kurpas D. Blood group and ıncidence of asthma and chronic obstructive pulmonary disease. Adv Exp Med Biol. 2018;1114:31-39. doi: 10.1007/5584_2018_203.
Referans5. Konuk S. Association between chronic obstructive pulmonary disease and blood types. J Clin Anal Med 2017;8(suppl 4): 395-398.
Referans6. Uwaezuoke SN, Eze JN, Ayuk AC, Ndu IK. ABO histo-blood group and risk of respiratory atopy in children: a review of published evidence. Pediatric Health Med Ther. 2018;9:73-79. doi: 10.2147/PHMT.S162570.
Referans7. Fenton TR. A new growth chart for preterm babies: Babson and Benda's chart updated with recent data and a new format. BMC Pediatr. 2003;3:13. doi: 10.1186/1471-2431-3-13.
Referans8. Satar M, Arısoy AE, Çelik İH. Turkish Neonatal Society guideline on neonatal infections-diagnosis and treatment. Turk Pediatri Ars. 2018;53(Suppl 1):S88-S100. doi: 10.5152/TurkPediatriArs.2018.01809.
Referans9. Bozkaya D, Dizdar EA, Korkut S, Ceran B, Alkan M, Oğuz ŞS. Evaluation of different types of natural surfactants by lung ultrasound in respiratory distress syndrome. Am J Perinatol. 2021;38(6):590-596. doi: 10.1055/s-0039-1700856.
Referans10. Cakir U, Tayman C, Yucel C. A novel diagnostic marker for the severity of bronchopulmonary dysplasia in very low birth weight ınfants: Interleukin-33. Pediatr Allergy Immunol Pulmonol. 2019;32(1):12-17. doi: 10.1089/ped.2019.0994.
Referans11. Chen YL, Chen JC, Lin TM, et al. ABO/secretor genetic complex is associated with the susceptibility of childhood asthma in Taiwan. Clin Exp Allergy. 2005;35(7):926-932. doi: 10.1111/j.1365-2222.2005.02278.x.
Referans12. Kauffmann F, Frette C, Pham QT, Nafissi S, Bertrand JP, Oriol R. Associations of blood group-related antigens to FEV1, wheezing, and asthma. Am J Respir Crit Care Med. 1996;153(1):76-82. doi: 10.1164/ajrccm.153.1.8542166.
Referans13. Cakir U, Tayman C, Buyuktiryaki M. An unknown risk factor for sepsis in very low birth weight preterms: ABO Blood Groups (BGaPS Study). Am J Perinatol. 2021;38(7):669-675. doi: 10.1055/s-0039-1700864.
Referans14. Tayman C, Çakır U. Do different blood groups affect the development of necrotizing enterocolitis? Med J SDU. 2019:26(4):382-388 doi: 10.17343/sdutfd.477641.
Referans15. McMahon KE, Habeeb O, Bautista GM, et al. The association between AB blood group and neonatal disease. J Neonatal Perinatal Med. 2019;12(1):81-86. doi: 10.3233/NPM-17115.
Referans16. Ceran B, Çakır U, Tuğcu AU, Tayman C. Effect of ABO blood groups on patent ductus arteriosus closure. Erciyes Med J. 2022;44(3): 330–333. doi: 10.14744/etd.2021.23855.
Referans17. Cakir U, Tayman C, Buyuktiryaki M. Unknown aspects of the relationship between ABO blood group system and preterm morbidities. Arch Argent Pediatr. 2020;118(2):e135-e142. doi: 10.5546/aap.2020.eng.e135.