Hüsnü EFENDİ, Mustafa ERTAŞ, Cumhur ERTEKİN

Parkinson Hastalığında Motor Uyarılmış Potansiyeller

Parkinson Hastalığı (PH), ileri yaşlarda en sık karşımıza çıkan extrapiramidal sendromdur. Başlıca belirtileri, tremor, rijidite, akinezi ve postüral instabilitedir. Tanı herhangi bir laboratuvar desteği olmadan klinik bulgulara dayanır. Bu çalışmada Parkinson hastalığı olan 13 hastada transkranial kortikal stimulasyon (TCCS) ile motor uyarılmış potansiyeller (MEP) incelendi. İstirahat, dorsal fleksiyon ve plantar fleksiyon gibi 3 deneysel paradigma ile alt extremiteden soleus ve tibialis anterior kaslarından kayıtlanan motor uyarılmış potansiyeller incelendi.

Anahtar Kelimeler:

Parkinson hastalığı, motor uyarılmış potansiyeller

Motor Evoked Potential in Parkinson's Disease

Idiopathic Parkinson's Disease (PD) is the most common extrapyramidal syndrome encountered in the aging population. The major signs of Parkinson's disease are tremor, rigidity, akinesia, and postural instability. The diagnosis of PD remains a Clinical judgement without any confirmatory laboratory diagnostic procedure available or required. In this study we made transcranial cortical stimulation (TCCS) in 13 PD patients and motor evoked potential (MEP) recorded from soleus and anterior tibial muscle. In all patients three experimental paradigmas were performed; rest, voluntary dorsiflexion, voluntary plantar flexion.

Keywords:

Parkinson's disease, motor evoked potential,

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