Elif GELENLİ DOLANBAY, Ayşe YILDIZ, Hakan AYDEMİR, Serhat ACAR, Hira ERSAN, Yusuf AKAR, Ferhat BAKİ

İNSAN ÜREME SİSTEMİ’NE COVID19 TEHDİDİ

Çin’in Wuhan kentinde ortaya çıkan ve eğitim, sağlık, ekonomi gibi birçok alanda büyük değişiklikler yapan Koronavirüs bütün dünyayı etkisi altına aldı. 2021 yılına geldiğimizde ise, Koronavirüsle yapılan mücadele kapsamında bir yandan dünya genelinde aşılama çalışmaları yapılırken bir yandan da virüsün insan sistemleri üzerine etkileri araştırılmaya devam etmektedir. İnsan sistemleri üzerine yapılan araştırma alanlarından biri de üreme sistemidir. Koronavirüsün ekspresse olduğu ACE2 (anjiyotensin dönüştürücü enzim 2) ve TMPRSS2 (transmembran serin proteaz 2) gibi yapılara baktığımız zaman insan üreme sistemi üzerine etkileri çok daha iyi anlaşılmaktadır. Koronavirüs nedenli karantina sürecinde hayatlarımıza giren ve beraberinde belirsizliğin de yol açtığı stresin; hem in vitro fertilizasyon çalışmalarındaki hem de insan üreme sistemi üzerindeki etkileri uzun yıllardır bilinmektedir. Yapılan çalışmalar Koronavirüsün insan üreme sisteminde bulunan hormonların miktarını ve yoğunluğunu değiştirdiğini göstermektedir. Koronavirüsün hayatımıza getirdiği stres, vücudu enfekte etmesi ve tedavisi insan üreme sistemi için bir takım potansiyel riskler oluşturmaktadır. Makalede de bu potansiyel riskler doğrultusunda yapılan araştırmalar derlenmiştir. ABSTRACT Coronavirus, which emerged in Wuhan, China has made major changes in many fields such as education, health, and economy, has influenced the world. When we come to 2021, while vaccination studies are carried out throughout the world within the scope of the fight against coronavirus, on the other hand, the effects of the virus on human systems are being investigated. One of the research areas on human systems is the reproductive system. When we look at the structures such as ACE2 (angiotensin converting enzyme 2) and TMPRSS2 (transmembrane serine protease 2) that coronavirus expresses, their effects on the human reproductive system are much better understood. The stress that entered our lives during the quarantine process due to coronavirus and also caused by uncertainty; Both in vitro fertilization studies and its effects on the human reproductive system have been known for many years. Studies show that the coronavirus changes the amount and density of hormones in the human reproductive system. The stress that the coronavirus brings to our lives, its infection and treatment pose some potential risks for the human reproductive system. In the article, researches conducted in line with these potential risks are compiled

Anahtar Kelimeler:

Virüsler, SARS-CoV-2, Üreme Sistemi, Hamilelik, COVID-19 Tedavisi, Virüsler, SARS-CoV-2, Üreme Sistemi, Hamilelik, COVID-19 Tedavisi

COVID19 THREAT TO HUMAN REPRODUCTIVE SYSTEM

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