Barış MÜLAYİM, Zeki ŞAHİNOĞLU, Sema MÜLAYİM, Habibe AYVACI, Umur KUYUMCUOĞLU

Postmenopozal semptomatik ve asemtomatik olgularda uterin arter doppler indeks, endometrial kalınlık ve histopatolojik bulguların karşılaştırılması

Objektif: Bu çalışmamızda, PMK'lı olgularda Doppler USG bulguları ve endometrium kalınlığının, endometrial patolojileri saptamadaki sensitivite ve spesifisitesini belirleyerek, Doppler USG nin bir tarama yöntemi olarak kullanılabilirliğini göstermeyi amaçladık. Planlama : Pro sp ektif Kohort Hastalar: Hormon replasman tedavisi almayan postmenopozal kanaması olan 57 olgu ve kontrol grubunu oluşturan postmenopozal kanaması olmayan 57 olgu. Girişim: Doppler Ultrasonografı, Endometrial Örnekleme. Değerlendirme: Endometrial örnekleme öncesi, endometrium kalınlıkları ve uterin arter doppler indeksleri belirlendi. Histo-patolojik bulgular ile endometrium kalınlığı ve uterin arter RI ve PI değerleri karşılaştırıldı. Sonuçlar %95'likgüven aralığında,p

Anahtar Kelimeler:

Postmenopoz, Histopatoloji, Endometriyum, Duyarlılık ve özgüllük, Ultrasonografi, doppler

Comparison of uterin artery doppler indices, endometrial thickness and histopathological findings of symptomatic and asymptomatic postmenopausal women

Objective: In this study we aimed to demonstrate the utility of Doppler Ultrasound (USG) as a screening tool by means of defining the sensitivity and specificity of Doppler USG findings and endometrial thickness in determining endometrial pathologies in postmenopausal women. Plan: Prospective Cohort Patients: 57 women with postmenopausal bleeding and 57 control women without postmenopausal bleeding. None of them received hormon replacement therapy. Tests: Doppler USG, Endometrial sampling Evaluation: Endometrial thickness and uterine artery Doppler indices were defined prior to endometrial sampling. Histopathological findings were compared with endometrial thickness and uterine artery RI and PI values. A p value of less than 0.05 was considered significant with a confidence interval of 95 %. Results: Sensitivity and specificity of endometrial thickness in (acceptedcut-off5.5 mm) determining endometrial pathologies were found to be % 76 and % 52. Sensitivity and specificity of uterine artery Doppler indices in determining endometrial pathologies were calculated alternately; right RI: 100%- 30%, leftRI: 83%- 52%, right PI: 100%-22%, left PI: 83%- 26%. Comment: Sensitivity and specificity of uterine artery Doppler indices in determining endometrial pathologies is significantly higher than sensitivity and specificity of endometrial thickness.

Keywords:

Postmenopause, Histopathology, Endometrium, Sensitivity and Specificity, Ultrasonography, Doppler,

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