Namık Kemal DURU, SEYİT TEMEL CEYHAN, İbrahim ALANBAY, Uğur KESKİN, Murat MUHCU, İskender BAŞER

Ovarian endometrioma boyutu ve anti müllerin hormon düzeylerinin korelasyonu

Amaç: Amaç, unilateral veya bilateral endometrioma stripping uygulanan hastalarda endometrioma boyutu ile AMH seviyeleri arasında korelasyon olup olmadığının gösterilmesi. Gereç ve Yöntem: Endometrioma boyutu 45 mm ve daha büyük olan 47 hasta seçildi. Bu vakalardan 33 vakada endometrioma unilateral, 14 hastada bilateraldi. Hastalardan operasyon öncesi ve operasyondan 1 ay sonrasında menstruel siklusun üçüncü gününde AMH, FSHve Estradiol için kan alındı. Bulgular: Preoperatif ve postoperatif AMH düzeyleri hem unilateral hem bilateral endometriomalı hastalarda endometrioma boyutu ile korelasyon göstermemektedir. Sonuç: Bu çalışmanın sonuçları endometrioma boyutunun folliküler havuz üzerinde hasar verici etkiye sahip olmadığını, kısa süreli izlemde ise, endometrioma stripping yönteminin AMH sekrete eden sağlıklı doku üzerinde hasar oluşturmadığını ve kist boyutu ile AMH seviyeleri arasında korelasyon gözlenmediğini ortaya koymuştur.

Anahtar Kelimeler:

Anti-Mullerian Hormon, Endometriyum, Endometriyoz, Folikül uyarıcı hormon, Östradiol

The corelation between anti Mullerian Hormone levels and size of endometrioma

Objective: To show whether there is a corelation between the size of endometrioma and AMH (Anti- Müllerian Hormon) levels in patients who undergo unilateral or bilateral endometrioma stripping. Material and Method: 47 patients with endometrioma of 45 mm or larger were chosen. Endometrioma was unilateral in 33 patients while bilateral in 14. Blood tests for AMH, FSH and estradiol were applied on the 3rd day of the menstruation period before and 1 month after the operation. Results : There was no corelation between levels ofpreoperative and postoperative AMH levels and size of endometrioma in unilateral or bilateral cases. Conclusion: The results of this study indicate that the size of endometrioma does not have a damaging effect on the follicle reserve. In short follow-ups, endometrioma stripping does not damage the healthy ovarian tissue secreting AMH and there is no corelation between AMH levels and the size of endometrioma.

Keywords:

Anti-Mullerian Hormone, Endometrium, Endometriosis, Follicle Stimulating Hormone, Estradiol,

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