Hülya YAVUZ, Suna CESUR, Ecmel KAYGUSUZ, Ateş KARATEKE

Osteoklast Benzeri Dev Hücreler İçeren Leiomyosarkom

Leiomyosarkomlar uterus malignitelerinin %1-3 ünü, uterus sarkomlarının ise üçte birini oluşturmaktadır(1). Nadir mikroskopik tiplerinden biri osteoklastik dev hücreler içeren tipidir. Günlük uygulamada nadir görülen leiomyosarkom vakalarının daha da nadir görülen bu alt tipi dev hücrelerin varlığı nedeniyle ayırıcı tanı güçlüğü yaratabilir. Literatürdeki immunhistokimyasal ve elektron mikroskopik çalışmalar bu hücrelerin epitelyal ve ya histiyosit kökenli olabileceğini düşündürmüştür

Leiomyosarcoma with Osteoclast Like Giant Cell

The leiomyosarcomas account for 1-3 % of uterine malignancies and 30 % of uterus sarcomas. The “osteoclastic” giant cell variant is a very rare microscopic type of the leiomyosarcomas. In daily practice, the cases of leiomyosarcomas are very rare and the osteoclastic variant is even rarer than them. Differential diagnosis of this variant is difficult because of giant cells in it. Immunhistochemical and electron microscopic studies indicate that, the origins of these cells are epithelial or histiocytic

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