Pulat Lale SEREN, Abdülkadir BOZAYKUT, N. SİPAHİER, S. KARAMAN

İnfantil spazm tanısı alan 16 olgunun retrospektif olarak değerlendirilmesi

Özet: infantil spazm, myoklonik konvülsiyon, hipsaritmik EEG ve mental retardasyon ile karakterize olan erken çocukluk döneminin en ciddi seyir gösteren epileptik sendromlarmdan biridir. Ocak 1997-Aralık2001 tarihleri arasında Zeynep Kamil Hastanesi Sütçocuğu Kliniği'nde infantil spazm tanısı alan 16 hasta retrospektif olarak değerlendirildi. Vakaların hastaneye geliş nedeni, kliniği, laboratuar bulguları incelemeye alındı. Olguların 8'i kız, 8'i erkekti. Spazmların ortalama başlama yaşı 4,8 ay ( l gün - 10 ay ) idi. Hastalan etyolojisine göre 9'u semptomatik, 7'si idiyopatik olarak bulundu. Vakaların 11'i durdurulamayan konvülsiyon, 3'ü bronkopnömoni, 2'si idrar yolu enfeksiyonu ve sepsis nedeni ile hastanemize interne edildi. Kliniğimize yatış nedenine bağlı tedavileri yapılan hastaların, infantil spazma yönelik tedavileri, pediatrik nöroloji tarafından düzenlendi. Biz de bu çalışmada infantil spazm tanısı alan 16 olguyu, literatür bilgileri eşliğinde gözden geçirerek sunmayı amaçladık.

Anahtar Kelimeler:

Olgu sunumu, Klinik inceleme, Geriyedönük çalışma, Spazmlar, infantil

The retrospective assessment of 16 patients with infantile spasms

Infantile spasm is one of the most catastrophic childhood epileptic syndromes which is characterized by myoclonic convulsion, hypsarrhythmia Electroencephalography and mental retardation. In this study, 16 patients who had been diagnosed as infantile spasm in Zeynep Kamil Maternith and Children's Hospital between January 1997-December 2001 were evaluated retrospectively. These patients were analyzed according to their clinical signs, laboratory tindings and the reason of admission to our hospital. Out of 16 patients, 8 were female and 8 were male. The mean age of the patients was 4,8 months. Nine of them were symptomatic, seven of them were idiopathic. Eleven of the patients were hospitalized for convulsion, three of them for lower respiratory tract infection and two of them for urinary tract infection. The patients were treated for their primary reason of hospitalization and then they were referred to pédiatrie neurology department for their medical therapy. In our study, we aimed to review infantil spasms by evaluating these 16 cases under literature information.

Keywords:

Case report, Clinical evaluation, Retrospective Studies, Spasms, Infantile,

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