Yüksel YILMAZ, Berna ŞENER, Handan ŞAHSUVAROĞLU, ENVER ATAY, Meral İNALHAN, Savaş İNAN

Febrile seizures: Clinical features of 96 patients

Anahtar Kelimeler:

Klinik bulgular, Nöbetler, febril, Çocuk, Araştırma teknikleri

Febrile seizures: Clinical features of 96 patients

Aim: This study was designed to investigate the clinical findings of the children with febrile seizure (FS). Patients: This study encompasses 96 patients with FS admitted to our Pediatric Neurology Division between January-December 1997. Results: The mean age at the time of the first FS was 16 months (5 months- 4.5 years). The incidence of a history of FS in the first and second degree relatives was 72 %. In 9.7% of the children a history of epilepsy in the family was noted. Generalized tonic (52.5%) and atonic (25.4%) seizures were the most common types of seizures. Seizures were classified as complex in 54.8% and simple in 46.2% of the cases. Status occurred in 16.1% of all cases. The recurrence rate was 83.9% and recurrence occurred in 50% of the cases within the first 6 months, in 84.9% within the first 12 months. Complex FS were determined in 80.5% of the children with recurrence, whereas in 26.7% of the patients without recurrence. Conclusion: FS are a common problem especially in children less than 3 years of age. The recurrence rate is high within the 12 months after the first FS and in patients with complicated FS.

Keywords:

Clinical findings, Seizures, Febrile, Child, Investigative Techniques,

___

1- Aicardi J: Epilepsy in children. New York:Raven Press, 1995; 212-219
2- Gökyiğit A, Çalışkan A. Febril konvülsiyon nedeniyle hastaneye getirilen ve profılaktik antiepileptik tedavi uygulanmayan 274 çocukta 10 yıl sonra epilepsi insidansı ve EEG bulguları. Tıp Fak Mecmuası 1990;53:l-7
3- Consensus Developmental Panel.: Febrile seizures: long term management of children with fever associated seizures. Pediatrics 1980;66:1009-12
4- Berg AT, Shinnar S: Complex febrile seizures
Epilepsia 1996;37: 126-33
5- Berg AT, Shinnar S, Hauser A et al: A prospective study of recurrent febrile seizures. New Engl J Med. 1992;327:1122-7
6-Berg AT, Shinnar S, Hauser WA, et al: Predictors of recurrent febrile seizures:a metaanalytic review. J Pediatr 1990; 116:329-37
7-Theodore-WH; Bhatia-S; Hatta-J; Fazilat-S; DeCarli-C; Bookheimer-SY; Gaillard-WD. Hippocampal atrophy, epilepsy duration, and febrile seizures in patients with partial seizures. Neurology. 1999 ;52: 132-6
8- Hauser WA, Annegers F: Prognosis of children with febrile seizures. In:Advances in Epileptology. Ed.Wolf P, Dam M, Janz F, Dreifuss E. New York:Raven Press 1987; 155-58
9- van Stuijvenberg M; Steyerberg EW; Derksen Lubsen G; Moll HA. Temperature, age, and recurrence of febrile seizure. Arch-Pediatr- Adolesc-Med. 1998; 152: 1170-5
10-Forsgreen L, Sidenvall R, Blomquist K, et al: A prospective incidence study of febrile convulsions. Acta Pediatr Scand. 1990;79:550-57
11- Ellenberg JH, Nelson KB: Sample selection and natural history of disease: studies of febrile seizures. JAMA 1980;243:1337-40
12- Rich SS, Annegers JF, Hauser AW, Anderson VE: Complex segregation analysis of febrile convulsions. Am J.Hum Genet. 1987;41:249-57
13-Doose H, Maurer A. Seizure risk in offspring of individuals with a history of febrile convulsions. Eur J Pediatr 1997; 156:476-481
14- Kugler SL; Johnson WG. Genetics of the febrile seizure susceptibility trait. Brain Dev 1998 ; 20: 265-74 15- Nelson KB, Ellenberg JH. Prognosis in children with febrile seizures. Pediatrics. 1978;61:720-27