Arslan Özlem ÜNLÜTÜRK, Özlem TEMEL, Müjgan ORAL, Serpil DEĞİRMENCİ, Savaş İNAN

Henoch-Schönlein purpuralı hastalarda renal ve gastrointestinal sistem tutulumla ilişkili klinik ve laboratuar bulgular

Henoch-Schönlein purpurası (HSP) nedeni kesin olarak bilinmeyen çeşitli antijenik uyarılarla meydana gelen immun komplekslerin yol açtığı kabul edilen bir hastalıktır. Daha çok belirgin cilt tutulumu ile seyreder, fakat visseral organlarda da benzer lezyonlar nedeni ile önemli sonuçlar doğurabilmektedir. Henoch-Schönlein purpuralı çocuklarda renal ve gastrointestinal sistem tutulumunu gösteren faktörleri araştırmak amacıyla yaş ortalaması 7.45 + 2.75 olan 72 çocuğu retrospektif olarak inceledik. Gastrointestinal sistem ve renal tutulum bulunan çocuklarda yaş ve IgA değerleri istatistiksel olarak anlamlı yüksek bulundu. Renal tutulum bulunanlarda hipertansiyon yüzdesi renal tutulum bulunmayanlardan anlamlı yüksek bulundu.

Anahtar Kelimeler:

Purpura, Schoenlein-Henoch, Antijen-antikor kompleksi, Geriyedönük çalışma, Hipertansiyon

Henoch-Schönlein purpuralı hastalarda renal ve gastrointestinal sistem tutulumla ilişkili klinik ve laboratuar bulgular

Henoch-Schoenlein purpura is a disorder of which etiology is not cleary understood and considered as an immuncomplex disease. HSP is generally presented with skin lesions but also similar lesions may occur at visceral organs and cause serious complications. In order to evaluate risk factors assciated with renal and gastrointestinal involvement in children with Henoch-Schoenlein purpura, we evaluaeted 72 children, aged 7.45±2.75 years, retrospectively. In children with nephritis and gastrointestinal involvement, age and IgA level were significantly higher than valves in children without nephrit and gastrointestinal involvement. And also in children with HSP nephrits the percent of hypertension was significantly higher than valves in children without nephritis.

Keywords:

Purpura, Schoenlein-Henoch, Antigen-Antibody Complex, Retrospective Studies, Hypertension,

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