Çocukluk çağı pnömonilerinde Mycoplazma pneumoniae'nin rolü

Mycoplasma Pneumoniae okul çağı çocukları ve genç erişkinlerin solunum, yolu enfeksiyonlarında primer etkendir Minik olarak önemli hastalıklar 3-4 yaş altı çocuklarda enderken ,peak insidans 5-15 yaş arasında oluşmaktadır.My coplasmanın neden olduğu hastalıklar genellikle hafif seyirli olup hospitalizasyon seyrektir. Çocukluk çağında Mycoplasma Pneumoniae pnömonisinin insidansını belirlemek amacıyla pnömoni tanısı almış 246 çocuk-ta Latex Aglütinasyon yöntemiyle Mycoplasma IgM Antikor'u bakıldı.5-15 yaş arası ayaktan tedavi edilen grupta, hospitalize edilerek tedavi edilenlere göre Mycoplasma IgM (+)'lik oranı anlamlı yüksek bulun-du. 5 yaşından küçük çocuklarda Mycoplasma Pneumoniae pnömonisi tespit edilmedi.

The role of Mycoplasma pneumoniae in childhood pneumoniaes

The role of mycoplasma pneumoniae in childhood pneumoniaes Mycoplasma Pneumoniae is a major cause of respira-tory infection in school -aged children and young adults.Clinically significant disease is unusual before the age of 3 to 4 y ear,the peak incidence occurs from 5 tol5 years. Mycoplasma illnesses are mild and hospitalisation is infrequent. In order to evaluate the incidence of Mycoplasma Pneumoniae pneumonia in children we evaluated the Mycoplasma IgM antibody in 246 pédiatrie patient diagnosed pneumonia by the method of Latex Aglutination.We found the positiv eness of Mycoplasma IgM anyibodies in the hospitalized children aged 5 to 15 years less than the ones who are not hospital-ized.We didn't find Mycoplasma Pneumoniae pneumo-nia in the children who are youn gerthan 5 years.

___

  • 1- Ramsey BW, Marcuse EK, Foy HM, et al. Use of bacterial antigen detection in the diagnosis of pediatric lower respiratory tract infections. Pediatrics 1986; 78: 1-9
  • 2- Turner RB, Lande AE, Chase P, Hilton N, Weinberg D
  • Pnemonia in pediatric outpatients: cause and clinical manifesta¬ tions. J. Pediatr 1987; 194-200 3- Ausina U, Coll P, Sambeat M, Puig I, et al. Prospective study on the etiology of community -acquired pneumonia in chidren and adults in spain. EurJ Clin Microbiol Infect Dis 1988; 7: 347-7
  • 4- Wallace AC. Clinical overview of typical Mycoplasma pneumonae infections. Ciln Infect Dis 1993; 17 (Suppl 1): 32-6 5- Claesson BA, Trollfers B, Brolin I, et al. Etiology of community- acquired pneumonia in chidren based on antibody responses to bacterial and viral antigens. Pediatr Infect Dis] 1989; 8: 856-62 6- Nohynek H, Eskola J, Laine E, et al. The causes of hospital- treated lower respiratory tract infection in children. Am J Child 1991; 145:618-22
  • 7- Gendrel D, Raymond], Moulin F, et al. Etiology and response to antimicrobial therapy of community-acquired pneumonia in French children. Fur] Clin Microbiol Infect Dis 1997; 16:388-91 8- Heiskanen-Kosma T,Korppi MJokinen C,et al.Etiology of childhood pneumoniaserological results of a prospective population -based study,.Pediatr Infect Dis S 1998;17:986-91
  • 9- Waris M. Toikka P. Saarinen T, et al. Diagnosis of Mycoplasma pneumoniae in children.] Clin Microbiol 1998;36: 3155-9
  • 10- Block S, Hedrick J, Hammerschlag M, Cassel GH, Craft JC
  • Mycoplasma pneumoniae and Chlamydia pneumoniae in pediatric community-acquired pneumonae comparative efficacy an safety of clarithromycin vs. orythromycin ethylsuccinate. Pediatr Infect Dis ] 1995; 14: 471-7
  • II- Cimolai N. Mycoplasma pneumoniae. Respiratory Infection
  • Pediatrics in Review 1998; 19: 327-31
  • 12- Ruuskanen O Nohyenek H,Ziegler T,et al.Pneumonia in childhood '.etiology response to antimicrobial therapy Fur J Clin Microbial Infect Dis 1992;11:217-23
  • 13- Wubbel L,Muniz L,Ahemed A ,et al.Etiology and treatment of community -acquired pneumonia in ambulatory children. Pediatry CİLT: 33 YIL: 2002 SAYI: 3 Infect Dis J 1999;98-104 14- Harris JA,Kolokathis A,Campell M,Casel GH,Hammerschlag MRSafety and efficiancy of azithromycin in the treatment of community -acquiredpneumonia in children Pediatry Infect Dis J 1998;17:865-71
  • 15- Fine NL, Smith LR, Sheedy Pf. Frequency of plevral effusions in mycoplasma and viral pneumonias. N Engl J Med 1970; 283: 790-3
  • 16- Foy HM. Infections caused by Mycoplasma pneumoniae and possible arrler state in different populatinos ofpatinets. Clin Infect Dis 1993; 17 (Suppl 1): 37-46
  • 17- MertsolaJ, Ziegler I. Ruusanen O, Vanto I. Recurrent wheezy bronchitis and viral respiratory infections. Arch Dis Child 1991; 66: 124-9
  • 18- Stevens D., Swift P.G.F., Johnston P.G.B., et al.: Mycoplasma pneumoniae infections in childrn. Arch Dis Child 53: 38-42, 1978
Zeynep Kamil Tıp Bülteni-Cover
  • ISSN: 1300-7971
  • Başlangıç: 1969
  • Yayıncı: Ali Cangül