Recep ASLAN, Mehmet Ramazan ŞEKEROĞLU, Fahir BAYIROĞLU

Serbest Radikal Türlerinin Membran Lipid Peroksidasyonuna Etkileri ve Hücresel Antioksidan Savunma

Bu makale, son yıllarda dikkatlerin üzerinde yoğunlaştığı radikaller ve antioksidanların neler olduğu, oluşumları, muhtemel etki mekanizmaları ve kaynaklarının tartışılmasını içermektedir. Ayrıca temel radikal reaksiyonları sonucu oluşan ürün tipleri tanımlanmaktadır. Aerobik canlılar oksijen metabolizması sırasında oksijen türevi serbest radikal üretimine karşılık bu radikallerin oluşturabileceği riskleri önlemeye yönelik enzimler ve kimyasallar taşırlar Makale ayrıca yaygın radikal kaynaklan ve antioksidan savunma sistemlerini de ele almaktadır.

Anahtar Kelimeler:

Lipid peroksidasyonu, Antioksidanlar, Hücre membranı

Effect of Free Radical Species on Membrane Lipid Peroxidation and Cellular Antioxidant Defense

In this article free radicals and antioxidants uıhich have become focus of attention with regard to their formation and mechanisms in recent years are discussed. Aerobic organismsgenerale oxygen derivated free radicals during oxygen metabolism, and they carry antioxidan Chemicals and enzymes which prevent or reduce the effect of these radicals. The more common sources of free radicals are described in the article and the methods used by cells to protect themselves from free radical damage, are described.

Keywords:

Lipid peroxidation, Antioxidants, Cell membrane,

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