Lokal ve lokal ileri evre Renal hücreli karsinomalarda cerrahi yaklaşım ve uzun dönem takip sonuçları: Tek merkez deneyimi

Amaç: Lokal ve lokal ileri evre renal hücreli kanserde altın standart tedavi cerrahidir. Cerrahi tedaviler parsiyel nefrektomi ve radikal nefrektomi olarak ayrılırken yöntem olarak ise açık, laparoskopik ve robotik yöntemler mevcuttur.Bu çalışmamızda lokal ve lokal ileri evre renal hücreli karsinomda cerrahi yaklaşımımızı ve uzun dönem takip sonuçlarımızı değerlendirmeyi amaçladık. Gereç Ve Yöntem: Çalışmaya Ocak 2011 ve şubat 2019 tarihleri arasında renal kitle nedeniyle cerrahi tedavi uygulanıp patoloji sonucu renal hücreli karsinom olarak raporlanan 119 hasta dahil edildi. Elde edilen veriler doğrultusunda hastalar retrospektif olarak incelendi. Bulgular: Çalışmaya dahil edilen 119 hastanın 76’sına radikal nefrektomi, 43’üne parsiyel nefrektomi yapıldı.82 hastanın patoloji sonucu berrak hücreli karsinom iken 21 hastanın papiller hücreli tip, 11 hastanın ise kromofob hücreli karsinom olduğu görüldü.En sık izlenen T evresi 33 hasta ise T2b olduğu görülürken en sık izlenen fuhrman derecesinin 48 hasta ile fuhrman derece 1 olduğu görüldü. Sonuç: Lokal ve lokal ileri evre Renal hücreli karsinom tedavisinde cerrahi en etkin ve güvenilir yöntemdir. Anahtar Kelimeler: Böbrek tümörü, nefrektomi, sonuçlar

Anahtar Kelimeler:

BÖBREK TÜMÖRÜ, NEFREKTOMİ, CERRAHİ SONUÇLAR

Surgical Approach and Long-Term Follow-Up Results in Locally And Locally Advanced Renal Cell Carcinomas: A Single Center Experience

Objective: Surgery is the gold standard treatment for locally and locally advanced renal cell cancer. However, data on long-term outcomes are limited. In this study, it was aimed to evaluate the surgical approach and long-term follow-up results in local and locally advanced renal cell carcinoma. Material and Method: 119 patients were included in this study who underwent surgical treatment for renal mass between January 2011 and February 2019 and were reported as renal cell carcinoma. Patients were analyzed retrospectively according to the data obtained. All patients were evaluated with contrast-enhanced computed tomography and/or magnetic resonance imaging preoperatively. Age, gender, tumor localization, tumor size, pathology result, blood transfusion, operation time, hospital stay, perioperative and postoperative complications of all patients were recorded. Results: Of the 119 patients who were included in the study, 76 underwent radical nephrectomy and 43 underwent partial nephrectomy. Radical nephrectomy was performed in 76 (63.9%) and partial nephrectomy in 43 (36.1%) of 119 patients included in the study. The pathology results of 82 patients were clear cell carcinoma, 21 patients were papillary cell carcinoma and 11 patients were chromophobe cell carcinomas. Patients who underwent open radical nephrectomy had a significantly longer hospital stay compared to laparoscopic radical nephrectomy. Warm ischemia time was found to be significantly higher in patients who underwent laparoscopic partial nephrectomy (p<0.025). Conclusion: Surgery is the most effective and reliable method in the treatment of locally and locally advanced renal cell carcinoma. Laparoscopic radical nephrectomy was found to be superior to open radical nephrectomy, especially with a shorter hospital stay. Long warm ischemia time in laparoscopic partial nephrectomy can be considered as a disadvantage compared to open partial nephrectomy.

Keywords:

Kidney tumor, Nephrectomy, Results,

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