Köpeklerde tiletamin-zolazepam ve tiletamin-zolazepam-xylazin anestezisi

Bu çalışma köpeklerde tiletamin-zolazepam ve tiletamin-zolazepam-xylazin kombinasyonlarının anestezik etkilerini araştırmak amacıyla değişik ırk, yaş, canlı ağırlık ve cinsiyette toplam 40 köpek üzerinde gerçekleştirildi. Birinci grup köpeklere n=20 tiletamin-zolazepam 10 mg/kg , 2. grup köpeklere n=20 ise tiletamin-zolazepam 10 mg/kg ve xylazin 1 mg/kg kombinasyonu im uygulandı. Anestezi öncesi, sırası ve anesteziden 24 saat sonra klinik bulgular, hematolojik parametreler ve biyokimyasal kan parametreleri ile ilgili sonuçlar belirlendi. İlaç uygulamasının hematolojik ve biyokimyasal kan parametrelerinde minimal etkiler meydana getirdiği, ayrıca iyi kas gevşemesi sağlayarak uygun anestezik koşullar oluşturduğu tespit edildi.Tiletamin-zolazepam uygulanan olgularda ortalama 5.9 dk'da indüksiyon ve 97 dk'lık şirurjikal anestezi süresi saklandı. Tiletamin-zolazepam-xylazin verilen köpeklerde ise ortalama 3.7 dk'da indüksiyon ve 101 dk süren şirurjikal anestezi süresi elde edildi. Buna göre her iki gruptaki köpeklerde tiletamin-zolazepam ve tiletamin-zolazepamxylazin kombinasyonlarının pratikte uygulanabileceği, tiletamin-zolazepam- xylazinle, tiletamin-zolazepamdan daha etkili ve daha uzun süreli anestezi sağlandığı ortaya konuldu

Anahtar Kelimeler:

Tiletamin, Zolazepam, Anestezi, Köpek

Tiletamin-zolazepam and tiletamin-zolazepam-xylazin anetsthesia in dogs

In this study the anesthetic effect of the combinations of tiletamin-zolazepam and tiletamin-zolazepam-xylazin were investigated in 40 dogs which were in different breed, age, body weight and sex. First group of dogs n=20 were injected with the combination of tiletamin-zolazepam 10 mg/kg and second group of dogs n=20 were injected with the combination of tiletamin-zolazepam 10 mg/kg plus xylazin 1 mg/kg intramuscularly. Clinical fındings, heamatological and biochemical parameters were recorded before, during and 24 hour after anesthesia. The results showed that both combinations had an excellent effect of muscular relaxation and positive anesthetic conditions. On the other hand, both combinations had a little effect on the heamatological and biochemical parameters. Dogs that injected with tiletamin-zolazepam had a mean value of 5.9 minutes induction period and 97 minutes surgical anesthetic duration. However, dogs that injected with tiletaminzolazepam-xylazin had a mean value of 3.7 minutes induction period and 101 minutes surgical anesthesia duration. In this study; results demonstrated that the combinations of tiletamin-zolazepam or tiletamin-zolazepam-xylazin can be used in practice as anesthetics. It was also found that the combination of tiletamin- zolazepam-xylazin is more effective anesthetic than the combination of tiletamin-zolazepam

Keywords:

Tiletamin, Zolazepam, Anesthesia, Dog,

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