___

• Acra AM, Sakagami H , Mats uta T , Adachi K, Otsuki S, Nak ajima H ve ark. Effect of thr ee fluor ide compounds on the growth of oral normal and tumor cells. In Vivo. 2012; 26(4) :657-64.
• Blumenthal DT, Sc hulman SF. Survival outco mes in glioblastoma multiforme,including the impact of adj uvant chemot her apy. Expert Rev Neurother . 2005;5(5):683-90.
• Boridy S, Le PU, Petr ecca K, Maysinger D. Celastrol tar gets proteostasis and acts synergistically with a heat-shock protein 90 inhibitor to kill human glioblastoma cells. Cell Death Dis. 2014; 5:e1216.
• Chen M, Rose AE, Doudican N, Osman I, Orlow SJ. Cel astrol synergistically enhances temozolomide cytotoxicity in melanoma cells. Mol Cancer Res. 2009;7(12):1946-53.
• Cloughesy TF, Landolfi J, Hogan DJ, Bloomfield S, Carter B, Chen CC, ve ark. Phase 1 trial of vocimagene amir etrorepv ec and 5- fluorocytosine for r ecurrent high- grade glioma. Sci Transl Med. 2016;8(341):341ra75.
• Di Cesar e Mannelli L, Piccolo M, Maione F, Ferraro MG, Ir ace C, De Feo V, ve ark. Tanshinones from Salvia miltiorrhiza Bunge revert chemother apy-induc ed neuropathic pain and reduce glioblastoma cells malignancy. Biomed Pharmacother . 2018;105:1042-1049.
• Haar CP, Hebbar P, Wallace GC 4th, Das A, Vandergrift WA 3rd, Smith JA. ve ark. Drug resistance in glioblastoma: a mini review. Neurochem Res. 2012;37(6):1192-200.
• Hanif F, Muzaffar K, Perveen K, Malhi SM, Simjee SU. Glioblastoma Multiforme: A Review of its Epidemiology and Pathogenesis through Clinical Presentation and Treatment. Asian Pac J Cancer Prev. 2017;18(1):3–9.
• Hu Y, Wang S, Wu X, Zhang J, Chen R, Chen M. ve ark. Chinese herbal medicine der ived compounds for cancer therapy: a focus on hepat ocellul ar carcinoma. J Ethnopharmaco l. 2013; 149(3):601-12.
• Kang CW, Park MS, Kim NH, Lee JH , Oh CW, Kim HR, ve ark. Hexane extract from Sar gassum serrat ifo lium inhibits the cell proliferat ion and metast atic ability of human glioblastoma U87MG cells. Oncol Rep. 2015; 34(5): 2602-8.
• Kim SH, Kang JG , Kim CS, Ihm SH, Choi MG, Yoo HJ, v e ark. Cytotoxic effect of celastrol alone or in combination with paclitaxel on anapl astic thyroid carcinoma cells. Tumour Biol. 2017; 39(5):1010428317698369.
• Krex D, Klınk B, Hartmann C, Von Deımlıng A, Pıetsch T, ve ark. Long-term survival with glioblastoma multiforme. Brain: A J Neurol. 2007;130:2596-606.
• Li N, Xu M, Bao N, Shi W, Li Q, Zhang X. v e ark. Discovery of novel NO-r eleasing celastrol derivatives with Hsp90 inhibitio n and cytotoxic act ivities. Eur J Med Chem. 2018; 160:1-8.
• Menei P, Jadaud E, Faisant N, Boisdron-Celle M, Michalak S, Fournier D, v e ark. Ster eotaxic implantation of 5- fluorour acil-rel easing micros pher es in mal ignant gl ioma. Cancer. 2004;100(2):405-10.
• Messaoudi K, Clavreul A, Lagarce F. Toward an effective strategy in glioblastoma treatment. Part I: resistance mechanisms and strategies to overcome resistance of glioblastoma to temozolomide. Drug Discov Today. 2015;20(7):899-905.
• Miller CR, Williams CR, Buchsbaum DJ, Gillespie GY. Intratumor al 5- fl uorourac il produc ed by cytosine deaminas e/5-fluorocytosine gene ther apy is effective for experimental human glioblasto mas. Canc er R es. 2002; 62(3):773- 80.
• Nutthasirikul N, Hahnvajanawong C, Techasen A, Limpaiboon T, Leelayuwat C,Chau-In S. ve ark. Tar geting the ∆133p53 isoform can restor e chemosens itivity in 5-fluorour acil- resistant cholangiocarcinoma cells. Int J Oncol. 2015; 47(6):2153-64.
• Paolillo M, Boselli C, Schinelli S. Glioblastoma under Siege: An Overview of Curr ent Therapeutic Str ategies . Brain Sci. 2018; 8(1).
• Sander P, Mostafa H, Soboh A, Schneider JM, Pala A, Baron AK ve ark. Vacquinol-1 inducible cell death in glioblastoma multiforme is counter regulated by TRPM7 activity induced by exogenous ATP. Oncotarget. 2017; (21):35124-35137.
• Sat hornsumetee S, Rich JN. Designer therapies for glioblastoma multiforme. Ann N Y Acad Sci. 2008; 1142:108-32.
• Tolba MF, Abdel-Rahman SZ. Pterostilbine, an act ive component of blueberries,sensitizes colon cancer cells to 5-fluorouracil cytotoxicity. Sci Rep. 2015;5: 15239.
• Touat M, Idbaih A, Sanson M, Ligon KL. Glioblastoma targeted therapy: updated approaches from recent biological insights. Ann Oncol. 2017;28(7):1457-1472.
• Uchibor i K, Kasamatsu A, Sunaga M, Yokota S, Sakur ada T, Kobayas hi E. ve ark. Est abl ishment and char acter izat ion of two 5-fl uorouracil-r esist ant hepatoc ellular carcinoma cell l ines. Int J Oncol. 2012; 40(4): 1005-10.
• Wang F, Zheng Z, Guan J, Qi D, Zhou S, Shen X v e ark. Ident ificat ion of a panel of genes as a prognostic biomarker for glioblastoma. EBioMedicine. 2018;37:68- 77.
• Wang Z, Zhai Z, Du X. Celastrol inhibits migr ation and invas ion through blocking the NF-κB pathway in ovarian cancer cells . Exp Ther Med. 2017;14(1):819-824.
• Zheng L, Fu Y, Zhuang L, Gai R, Ma J, Lou J. et . al. Simult aneous NF-κB inhibit ion and E-cadherin upregulation mediate mutually synergistic anticancer activity of celastrol and SAHA in vitro and in vivo. Int J Cancer. 2014;135(7):1721- 32.
• Zhu H, Yang W, He LJ, Ding WJ, Zheng L, Liao SD. et al. Upregulating Noxa by ER stress, celastrol exerts synergistic anti-cancer activity in comb ination wit h ABT- 737 in human hepatocellular carcinoma cells. PLo S One. 2012; 7(12):e52333.