ESWL tedavisi gören hastalarda serum böbrek fonksiyon değerlerinde herhangi bir değişiklik olur mu?

Amaç: Bu çalışmanın amacı, ESWL(Extracorporeal Shock Wave Lithotripsy) tedavisinin böbrek fonksiyon değerleri üzerine olan etkilerini incelemektir. Gereç ve Yöntemler: Kasım 2019 ve Ekim 2020 tarihleri arasında, böbrek taşı nedeniyle ESWL tedavisi yapılan ve çalışma kriterlerine uyan 50 erişkin hasta ile gerçekleştirildi. Ürogenital anomalisi olan ve soliter böbrekli hastalar çalışmaya alınmamıştır. Hastaların ortalama yaşı 37,2(26-67) idi. Hastaların 31'i(%62) erkek, 19'u(%38) kadındı. Hastalara 3 seans ESWL yapıldı ve seanslar arası süre 7 gün olarak belirlendi. İlk ESWL seansından bir gün önce rutin serum değerleri (Rutin I) alındı, ilk ESWL seansından bir gün sonra (Rutin II) ve 3. ESWL seansından bir gün sonra (Rutin III) tekrarlandı. Bulgular: Kan serumu elektrolit değerleri, serum kreatinin değeri, glomerül filtrasyon hızı(GFR) ve bikarbonat değerlerinin rutinler arasında istatistiksel olarak farklı olmadığı görüldü. Sonuç: Çalışmamızda elde ettiğimiz bulgulara göre, ESWL'nin üst üriner sistem taşlarının tedavisinde kullanımının hastalarda böbrek tübüllerinde disfonksiyona yol açmadığı, böbrek fonksiyon değerlerinin takibine gerek olmadığını göstermektedir.

Anahtar Kelimeler:

Extracorporeal Shock Wave Lithotripsy, böbrek taşı, renal fonksiyon, glomerüler filtrasyon hızı, GFR, ESWL

Are there any changes in serum renal parameters in patients undergoing ESWL therapy?

Purpose: The goal of this research was to explain the effects of ESWL on renal function (Extracorporeal Shock Wave Lithotripsy). Materials and Methods: This study was carried out retrospectively between November 2019 and October 2020, with 50 adult patients scheduled to perform an ESWL treatment because of a diagnosis of kidney stone and to completed the study protocol. In all of these patients, there was no urogenital abnormality, and none had a solitary kidney. Patients' mean age was 37.2 (between 26 and 67 years of age). Of patients, 31 (62%) were male and 19 (38%) were female. Three ESWL sessions were carried out in the patients and the time between sessions was set at 7 days. The routines collected one day before the ESWL (Routine I) protocol were repeated one day after the first session (Routine II) and one day after the end of all ESWL (Routine III) sessions. Results: There wasn’t any statistically significant difference among routines in terms of the ratio of serum electrolytes, serum creatinine, GFR and spot urine/protein. Conclusion: The findings indicate that the renal function tests do not need to assess whether ESWL leads to a tubular functional dysfunction in patients when treating upper urinary system stone disease. Keywords: Extracorporeal Shock Wave Lithotripsy (ESWL), renal stone, renal function and glomerular filtration rate (GFR)

Keywords:

Extracorporeal Shock Wave Lithotripsy, ESWL, renal stone, renal function, glomerular filtration rate, GFR,

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