Solunum güçlülüğü ile seyreden buzağı pneumonilerinin tedavisinde clenbuterol'ün etkisi

Bu araştırmada solunum güçlüğü (dispne) ile seyreden 2-3 aylık, 20 bronkopnömonili buzağıda clenbuterolün kısa süreli etkileri klinik düzeyde değerlendirildi. Bu amaçla her bir buzağıya 0.8/j.g/kg dozunda, intravenöz yolla clenbuterol uygulandı. Uygulama sonrası 5., 10., 15., 20., 25. ve 30. dakikalarda klinik muayeneler tekrarlandı ve solunum güçlüğühdeki değişiklikler kaydedildi. Kalp frekansı ve solunum sayısının clenbuterolün etkisiyle kontrol değerlerine göre azaldığı (p

Effect of clenbuterol in the treatment of pneumonic calves with dyspnea

In this study, early effects of clenbuterol were clinically evaluated in 20 pneumonic calves, aged from 2-3 month, with dyspnea. For this purpose,clenbuterol was given at the dose of 0.8fig/kg intravenously for each affected calf. Clinical examinations were done and changes of dyspnea status were noted at the 5th, l(f, 15th, 2(fh, 25^ and 30th minutes after the administration of clenbuterol. It was observed that heart and respiratory rate were reduced as compared to the control values (p<0.05); additionally, the clinical index scores were significantly decreased as well (p<0.05). It was determined that dyspnea status were disappeared at the 5 and 25th minutes in two calves, at the Iff1 minute in five calves, at the 15th minute in three calves; dyspnea was lasted although the severity ofwheez'y respiration was decrased in the rest of calves. After monitoring period, antibiotics, fluids and anti-inflammatory drugs were given to each calf with dyspnea. Two of them died at the 30th minutes of monitoring period, one of them died within 12 hour. It was concluded that clenbuterol might be used to treat the pneumonic calves with dyspnea.