Cryptosporidium parvum' un buluşmasında su ve gıdaların rolü

Cryptosporidium parvum (C.parvum), cryptosporodiosis salgınlarına yol açan tehlikeli protozoon bir parazittir. Bu parazit çeşitli çevresel stres koşullarına ve gıda işleme prosedürlerine dirençli olan ookist formunda, kontamine su ve çiğ gıdalar ile nakledilebilmektedir. Gıda maddelerinin işlenmesi sırasında C.parvum ile bulaşık suların kullanılması etkenin gıda işletmelerine girişinde potansiyel bir kaynak olarak görülmektedir. Bu derlemede, su ve gıdaların etkenin bulaşmasındaki rolü ve gıda zincirinden bu paraziti elimine etmede gıda endüstrisinde uygulanabilecek işletme kontrolleri üzerinde durulacaktır.

Anahtar Kelimeler:

Cryptosporidium parvum, insan, insan hastalıkları, gıda kaynaklı hastalıklar, hastalık bulaşması, cryptosporidiosis, içme suyu, gıda bulaşıklılığı, çiğ gıdalar, genel bakış

The role of water and foods in the transmission of Cryptosporidium parvum

Cryptosporidium parvum (C.parvum) is a emerging protozoan parasite responsible for several serious outbreaks of cryptosporidiosis. This parasite can be transmitted through contaminated water and raw food in the oocyst form, which is resistant to many environmental stresses and food processes. Employment of contaminated water in the production of foodstuffs may represent an important potential source of entry into food processing. This review article aims to examine the transmission of the pathogen via waters and foods, and processing controls that may be beneficial to the food industry to help eliminate this parasite from the human foodchain.

Keywords:

Cryptosporidium parvum, man, human diseases, foodborne diseases, disease transmission, cryptosporidiosis, drinking water, food contamination, raw foods, reviews,

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1. ARORA H, LECHEVALLIER M, BATTIGELLI D. Effectiveness of Chlorine Dioxide in Meeting the Enhanced Surface Water Treatment and Disinfection By-Products Rules. J. Water STR, 2001; 50: 209-227.

2. BELOSEVIC M, CRAIK SA, STAFFORD JL, NEUMANN NF, KRUITHOF J, SMITH DW. Studies on the Resistance/Reactivation of Giardia muris Cysts and Cryptosporidium parvum Oocysts Exposed to Medium-Pressure Ultraviolet Radiation. FEMS Microbiol. Let., 2001; 204: 197- 203.

3. BESSER-WIEK JW, FORFANG J, HEDBERG CW, KORLATH JA, OSTERHOLM MT. Foodborne Outbreak of Diarrheal Illness Associated with Cryptosporidium parvum- Minnesota 1995. Morbid. Mortal. Wkly. Rep., 1996; 45: 783.

4. CHALMERS RM, ELWIN K, REILLY WJ, IRVINE H, THOMAS AL, HUNTER PR. Cryptosporidium in Farmed Animals: The Detection of a Novel Isolate in Sheep. Int. J. Parasitol., 2002; 32: 21-26.

5. CHALMERS RM, STURDEE AP, MELLORS P, NICHOLSON V, LAWLOR F, KENNY F, TIMPSON P. Cryptosporidium parvum in Environmental Samples in the Sligo Area, Republic of Ireland: A Preliminary Report. Lett. Appl. Microbiol., 1997; 25: 380-384.

6. CHAURET CP, RADZIMINSKI CZ, LEPUIL M, CREASON R, ANDREWS RC. Chlorine Dioxide Inactivation of Cryptosporidium parvum Oocysts and Bacterial Spore Indicators. Appl. Environ. Microbiol., 2001; 67: 2993-3001.

7. CLARK DP. New Insights into Human Cryptosporidiosis. Clin. Microbiol. Rev., 1999; 12: 554-563.

8. CRAIK SA, WELDON D, FINCH GR, BOLTON JR, BELOSEVIC M. Inactivation of Cryptosporidium parvum Oocysts Using Medium and Low Pressure Ultraviolet Radiation. Wat. Res., 2001; 35: 1387-1398.

9. D’ANTONIO RG, WINN RE, TAYLOR JP. A Waterborne Outbreak of Cryptosporidiosis in Normal Hosts. Ann. Intern. Med., 1985; 103: 886- 888.

10. DENG MQ, CLIVER DO. Cryptosporidium parvum Studies with Dairy Products. Int. J. Food Microbiol., 1999; 46: 113-121.

11. DENG MQ, CLIVER DO. Inhactivation of Cryptosporidium parvum Oocysts in Cider by Flash Pasteurization. J. Food Prot., 2001; 64: 523- 527.

12. DI PINTO A, TANTILLO MG. Direct Detection of Cryptosporidium parvum Oocysts by Immunomagnetic Separation-Polymerase Chain Reaction in Raw Milk. J. Food Protect., 2002; 65: 1345-1348.

13. DRESCHER AC, GREENE DM, GADGIL AJ. Cryptosporidium Inactivation by Low-Pressure UV in a Water Disinfection Device. J. Environ. Heal., 2001; 64: 31-35.

14. DRIEDGER AM, RENNECKER JL, MARINAS BJ. Inactivation of Cryptosporidium parvum Oocysts with Ozone and Monochloramine at Low Temperature. Wat. Res., 2001; 35: 41-48.

15. FAYER R, LEWIS EJ, TROUT JM, GRACZYK TK, JENKINS MC, HIGGINS J, XIAO L, LAL AA. Cryptosporidium parvum in Oysters from Commercial Harvesting Sites in the Chesapeake Bay. Emerg. Infect. Dis., 1999; 5: 706-710.

16. FAYER R, MORGAN U, UPTON SJ. Epidemiology of Cryptosporidium: Transmission, Detection and Identification. Int. J. Parasitol., 2000; 30: 1305-1322.

17. GELLETLI R, STUART J, SOLTANO N, ARMSTRONG R, NICHOLS G. Cryptosporidiosis Associated with School Milk. Lancet, 1997; 350: 1005-1006.

18. GOMEZ-BAUTISTA M, ORTEGA-MORA L, TABARES E, LOPEZ-RODAS V, COSTAS E. Detection of Infectious Cryptosporidium parvum Oocysts in Mussels (Mytilus galloprovincialis) and Cockles (Cerastoderma edule). Appl. Environ. Microbiol., 2000; 66: 1866-1870.

19. GRACZYK TK, FAYER R, LEWIS EJ, TROUT JM, FARLEY CA. Cryptosporidium Oocysts in Bent Mussels (Ischadium recurvum) in the Chesapeake Bay. Parasitol. Res., 1999; 85: 518- 520.

20. HARP JA, FAYER R, PESCH BA, JACKSON GJ. Effect of Pasteurization on Infectivity of Cryptosporidium parvum Oocysts in Water and Milk. Appl. Environ. Microbiol., 1996; 62: 2866- 2868.

21. HAYES EB, MATTE TD, O’BRIEN TR, MCKINLEY TW, LOGSDON GS, ROSE JB, UNGAR BL, WORD DM, PINSKY PF, CUMMINGS ML. Large Community Outbreak of Cryptosporidiosis due to Contamination of a Filtered Public Water Supply. N. Eng. J. Med., 1989; 320:1372-1376.

22. HOWE AD, FORSTER S, MORTON S, MARSHALL R, OSBORN KS, WRİGHT P, HUNTER PR. Cryptosporidium Oocysts in a Water Supply Associated with a Cryptosporidiosis Outbreak. Emer. Infect. Dis., 2002; 8: 619-624.

23. HUNTER PR, NICHOLS G. Epidemiology and Clinical Features of Cryptosporidium Infection in Immunocompromised Patients. Clin. Microbiol. Rev., 2002; 15: 145-154.

24. IZUMIYAMA S, FURUKAWA I, KUROKI T, YAMAI S, SUGIYAMA H, YAGITA K, ENDO T. Prevalence of Cryptosporidium parvum Infections in Weaned Piglets and Fattening Porkers in Kanagawa, Prefecture, Japan. Jap. J. Infect. Dis., 2001; 54: 23-26.

25. KORICH DG, MEAD JR, MADORE MS, SINCLAIR NA, STERLING CR. Effects of Ozone, Chlorine Dioxide, Chlorine and Monochloramine on Cryptosporidium parvum Oocyst Viability. Appl. Environ. Microbiol., 1990; 56: 1423-1428.

26. KOSEK M, ALCANTARA C, LIMA AAM, GUERRANT RL. Cryptosporidiosis: An Update. Lancet Inf. Dis., 2001; 1: 262-269.

27. LABERGE I, GRIFFITHS MW, Prevalance, Detection and Control of Cryptosporidium parvum in Food. Int. J. Food Microbiol., 1996; 32: 1-26.

28. LECHEVALLIER MW, NORTON WD. Occurence of Giardia and Cryptosporidium spp. in Raw and Finished Drinking Water. J. Am. Water Works Assoc., 1996; 87: 54-68.

29. LECHEVALLIER MW, NORTON WD, LEE RG. Occurence of Giardia and Cryptosporidium spp. in Surface Water Supplies. Appl. Environ. Microbiol., 1991; 57:2610-2616.

30. MACKENZIE WR, HOXIE NJ, PROCTOR ME, GRADUS MS, BLAIR KA, PETERSON DE, KAZMIERCZAK JJ, ADDISS DG, FOX KR, ROSE JB. A Massive Outbreak in Milwaukee of Cryptosporidium Infection Transmitted Through the Public Water Supply. N.Eng.J.Med., 1994; 33: 161-167.

31. MEAD PS, SLUTSKER L, DIETZ V, MCCAIG LF, BRESEE JS, GRIFFIN PM, TAUXE RV. Food-Related Illness and Death in the United States. Emerg. Infect. Dis., 1999; 5: 607-624.

32. MILLAR BC, FINN M, XIAO L, LOWERY CJ, DOOLEY JSG, MOORE JE. Cryptosporidium in Foodstuffs-An Emerging Aetiological Route of Human Foodborne Illness. Trends Food Sci. Technol., 2002; 13: 168-187.

33. MONGE R, CHINCHILLA M. Presence of Cryptosporidium Oocysts in Fresh Vegetables. J. Food Protect., 1996; 59: 202-203.

34. PEETERS JE, MAZAS EA, MASSCHELEIN WJ, DEMATURANA IVM, DEBACKER E. Effect of Disenfection of Drinking Water with Ozone or Chlorine Dioxide on Survival of Cryptosporidium parvum Oocysts. Appl. Environ. Microbiol., 1989; 55: 1519-1522.

35. PENG MM, XIAO L, FREEMAN AR, ARROWOOD MJ, ESCALANTE AA, WELTMAN AC, ONG CS, MACKENZIE WR, LAL AA, BEARD CB. Genetic Polymorphism Among Cryptosporidium parvum Isolates: Evidence of Two Distinct Human Transmission Cycles. Emer. Infect. Dis., 1997; 3: 567-573.

36. QUIROZ ES, BERN C, MACARTHUR JR, XIAO L, FLETCHER M, ARROWOOD MJ, SHAY DK, LEVY ME, GLASS RI, LAL A. An Outbreak of Cryptosporodiosis Linked to a Foodhandler. J. Infect. Dis., 2000; 181: 695-700.

37. TRUDI FAHEY MD. Cryptosporidiosis. Infect. Dis., 2003; 10: 75-80.

38. ZU SX, LI JF, BARRETT LJ, FAYER R, SHU SY, McAULIFFE JF, ROCHE JK, GUERRANT RL. Seroepidemiologic Study of Cryptosporidium Infection in Children From Rural Communities of Anhui, China and Fortaleza, Brazil. Am. J. Trop. Med. Hyg., 1994; 51: 1-10.

39. ZUCKERMAN U, GOLD D, SHELEF G, ARMON R. The Presence of Giardia and Cryptosporidium in Surface Waters and Effluents in Israel. Water Sci. Technol., 1997; 35: 381-384.