Ankita AWASTHI, Bhaskar GUPTA, Papiya BIGONIYA

Beslenme Faktörlerinin Obeziteye Bağlı Komplikasyonlar Üzerindeki Etkisi: Hipotiroidizm, Dislipidemi ve Hormonal Dengesizlik

Obezite, dünya çapında yaygın olan en önemli yaşam tarzı bozukluklarından biridir. Artan obezite oranı, tiroid disfonksiyonu, dislipidemi, hormonal dengesizlik vb. hastalıkların ortaya çıkması ile ilişkilidir. Obezite, kalp hastalığı, ateroskleroz, insülin direnci, artrit, kas-iskelet sistemi bozuklukları ve kanser için risk faktörüdür. Bu makale, obezitenin dislipidemi, diyabet, hormonal dengesizlik ve hipotiroidizm ile ilişkisine dair içgörüler sunmaktadır. Leptin, insülin, seks hormonları ve büyüme hormonları iştahı, metabolizmayı ve vücut yağ dağılımını etkilediğinden hormonların aşırı veya yetersiz salınımı obeziteye yol açabilir. Makale, metabolik düzensizliğin obezite ile ilişkisi ve ilgili hastalıkların daha da geliştirilmesi hakkında bir inceleme sunmaktadır. Bu makale aynı zamanda diyet liflerinin ve balık proteininin metabolik değişiklikler, hormonal dengesizlik ve obezite ile ilişkili hiperlipidemi üzerindeki etkilerini de özetlemektedir. Bu makale, obezite ile ilgili bozuklukları yönetmek için yararlı olan lif ve diyet protein tüketimi gibi diyet müdahalesinin rolünü detaylandırdı. Potansiyel nutrasötik ürünler sık besin kaynakları olarak tüketilmektedir. Yine de, kaliteli insan klinik deney verileri eksiktir, bu da nutrasötiklerin güvenliğini ve etkinliğini değerlendirmek için önemli bilimsel çalışmalara ihtiyaç olduğunu gösterir.

Anahtar Kelimeler:

Dislipidemi, Hormonal dengesizlik, Diyabet, Leptin, Adiponektin, Omentin, Diyet lifi, Protein

Impact of Dietary Factors on Obesity Management and Its Correlation with Hypothyroidism, Dyslipidaemia and Hormonal Imbalance

Obesity is one of the major lifestyle disorders prevalent worldwide. The increasing obesity rate is associated with the emergence of diseases like thyroid dysfunction, dyslipidaemia, hormonal imbalance, etc. Obesity is the risk factor for heart disease, atherosclerosis, insulin resistance, arthritis, musculoskeletal disorders, and cancer. The present article portrays insights into the association of obesity with dyslipidemia, diabetes, hormonal imbalance, and hypothyroidism. Excessive or insufficient release of hormones can lead to obesity as leptin, insulin, sex hormones, and growth hormones influence appetite, metabolism, and body fat distribution. The article provides a review of the interrelationship of metabolic dysregulation with obesity and the further development of related diseases. This paper also summarizes the effects of dietary fibers and fish protein on metabolic alterations, hormonal imbalance, and hyperlipidemia associated with obesity. This article elaborated the role of dietary intervention like fiber and dietary protein consumption useful for managing obesity-related disorders. Potential nutraceutical products are consumed as frequent food sources. Still, quality human clinical trial data are lacking, signifying the need for substantial scientific work to assess the safety and efficacy of nutraceuticals.

Keywords:

Dyslipidaemia, Hormonal imbalance, Diabetes, Leptin, Adiponectin, Omentin, Dietary fibre, Protein,

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