Mehmet TÜRKMEN, Yeşim ÖZTÜRK, Meral BAYRAM TORUN, Demet ALAYGUT EYLENOĞLU, Alper SOYLU, Mustafa KIR

Anazarka Tarzı Ödem ile Başvuran İki̇ Sütçocuğu: Protei̇n Kaybetti̇ren Enteropati̇ti̇

Protein kaybettiren enteropati (PKE) serum proteinlerinin gastrointestinal sistemden kaybı ve hipoproteinemi gelişimiile karakterize bir tablodur. Ödem, asit, malnütrisyon plevral veperikardiyal efüzyon ile komplike hale gelebilir. Nadirgörülmekle birlikte bir çok durum PKEye neden olabilir. PKE nedenleri eroziv- noneroziv gastrointestinal hastalıklar,santral venöz basınç artışı ile karakterize hastalıklar ve mezenterik lenfatik obstrüksiyon gelişimi ile karakterize olanlarolarak gruplanabilir. PKE tanısı, hipoproteinemi ile başvuran bir hastada malnütrisyon, proteinüri ve bozulmuş proteinsentezi ile giden hastalıklar dışlandıktan sonra konulmalıdır. Tedavi, diyet modiﬁ kasyonunu da içeren destek tedavidenoluşur. Bu yazıda, farklı nedenlerle anazarka tarzı ödem ile başvuran ve farklı etiyolojilerle protein kaybettiren enteropatitanısı alan iki sütçocuğu sunulmuştur.

Two Infants Applying with Anasarca-Type Edema: Protein-Losing Enteropathy

rotein-losing enteropathy (PLE) is characterized by the development of hypoproteinemia and the loss of serum proteinsfrom the gastrointestinal system. It can be complicated with edema, acid, malnutrition, and pleural and pericardialeffusion. PLE is rare but has many causes. The reasons can be grouped as erosive and non-erosive gastrointestinaldiseases, diseases characterized by central venous pressure increase, and diseases characterized by the developmentof mesenteric lymphatic obstruction. A PLE diagnosis should be made for the patient who presents with hypoproteinemiaafter excluding other disorders causing malnutrition, proteinuria and impaired protein synthesis. Treatment consists of asupportive treatment that includes dietary modiﬁ cation. This paper presents two infants who developed anasarca-typeedema following different causes and were diagnosed with protein-losing enteropathy due to different etiologies.

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