Massive toxoplasma abortions in a dairy sheep flock and therapeutic approach with different doses of sulfadimidine
In a 500 head dairy sheep flock in Northern Greece, massive abortions (60%) were observed at 110-130 days of gestation. Attempts were made to treat the abortions with oxytetracyclin L.A. 20% but they were not successful. Toxoplasmosis was confirmed by laboratory examination of blood sera of ewes, aborted fetuses, and fetal brain samples. The remaining 200 pregnant sheep were divided in 2 groups of 100 ewes each. Animals of Group 1 were treated with 20 mg/kg b.w. sulfadimidine every other day 4 times, while the animals in Group 2 received 33 mg/kg b.w. sulfadimidine every other day 4 times via i.m. route. Considerable reductions in abortions were observed. The treatments were more effective in Group 2. Lactation started in both groups after treatment and satisfactory milk was produced.
Massive toxoplasma abortions in a dairy sheep flock and therapeutic approach with different doses of sulfadimidine
In a 500 head dairy sheep flock in Northern Greece, massive abortions (60%) were observed at 110-130 days of gestation. Attempts were made to treat the abortions with oxytetracyclin L.A. 20% but they were not successful. Toxoplasmosis was confirmed by laboratory examination of blood sera of ewes, aborted fetuses, and fetal brain samples. The remaining 200 pregnant sheep were divided in 2 groups of 100 ewes each. Animals of Group 1 were treated with 20 mg/kg b.w. sulfadimidine every other day 4 times, while the animals in Group 2 received 33 mg/kg b.w. sulfadimidine every other day 4 times via i.m. route. Considerable reductions in abortions were observed. The treatments were more effective in Group 2. Lactation started in both groups after treatment and satisfactory milk was produced.
___
- Dubey, J.P., Lindsay, D.S.: Neosporosis, toxoplasmosis and sarcocystosis in ruminants. Vet. Clin. North Am.-Food Anim. Pract., 2006; 22: 645-671.
- Buxton, D., Rodger, S.M.: Toxoplasmosis and neosporosis. In: Diseases of Sheep, 4th ed., Blackwell Publishing, London, 2007; 112-119.
- Mobini, S., Heath, A.M., Pugh, D.G.: Th eriogenology of sheep and goats. In: Sheep and Goat Medicine, Saunders, Philadelphia, 2002; 183-184.
- Diakou, A., Papadopoulos, E., Panousis, N., Giadinis, N., Karatzias, C.: Toxoplasma gondii and Neospora spp. infection in sheep and goats mixed stock farming. In: Proceedings of the 6th International Sheep Veterinary Congress, Fthenakis GC and McKaller QA, editors, Crete, Greece, June 2005. 5. Buxton, D., Blewett, D.A., Trees, A.J., McColgan, C., Finlayson, J.: Further studies in the use of monensin in the control of experimental ovine toxoplasmosis. J. Comp. Pathol., 1988; 98: 225-236.
- Buxton, D., Th omson, K.M., Maley, S.: Treatment of ovine toxoplasmosis with a combination of sulphamezathine and pyrimethamine. Vet. Rec., 1993; 132: 409-411.
- Buxton, D., Wright, S., Maley, S.W., Th omson, K.M., Brebner, J., Millard, K.: Decoquinate and the control of experimental ovine toxoplasmosis. Vet. Rec., 1996; 138: 434-436.
- Siarkou, V., Lambropoulos, A.F., Chrisafi , S., Kotsis, A., Papadopoulos, O.: Subspecies variation in Greek strains of Chlamydophila abortus. Vet. Microb, 2002; 85: 45–157.
- Dubey, J.P.: Pathogenecity and infectivity of Toxoplasma gondii oocysts for rats. J. Paras., 1996; 82: 951-956.
- Haralabidis, S.Th .: Th e immunodiagnosis of the parasitic diseases and the immunoenzyme assay ELISA. Monography. Scientifi c Yearbook of the Veterinary Faculty of the Aristotle University of Th essaloniki 1984; 22: 75-253 (article in Greek with English abstract).
- Plant, J.W.: Toxoplasmosis in sheep in New South Wales. In: Proceedings of the 6th International Sheep Veterinary Congress, Fthenakis GC and McKaller QA, editors, Crete, Greece, June 2005.
- Radostits, O.M., Gay, C.C., Blood, D.C., Hinchcliff , K.W.: Toxoplasmosis. In: Veterinary Medicine, 9th ed.,WB Saunders co, London, 2000; 1317-1322 .
- Buxton, D., Maley, S.W., Wright, S.E., Rodger, S., Bartley, P., Innes, E.A.: Toxoplasma gondii and ovine toxoplasmosis: New aspects of an old story. Vet. Paras., 2007; 149: 25-28.
- Smokovitis, A.: Th e udder. In: Physiology, 2nd ed., Kyriakidis co, Th essaloniki, 1990; 506-549.
- Clarkson, M.J., Faull, W.B.: Toxoplasmosis. In: A handbook for the sheep clinician, 4th ed. University Liverpool Press, Liverpool, 1990; 56-58.