The reliability and validity of the Turkish version of theNeuropsychiatric Inventory-Clinician

Background/aim: The Neuropsychiatric Inventory-Clinician (NPI-C) scale is one of the best-known scales for evaluating the behavioral and psychological symptoms of dementia. This study aimed to assess the reliability and validity of the Turkish version of the NPI-C scale in patients with Alzheimer disease (AD). Materials and methods: The NPI-C scale was administered to 125 patients with AD. For reliability, both Cronbach's α and interrater reliability were analyzed. The Behavioral Pathology in Alzheimer's Disease (BEHAVE-AD) scale was applied for validity and, in addition, the Mini Mental State Examination (MMSE), Instrumental Activities of Daily Living (IADL) scale, and Disability Assessment of Dementia (DAD) scale were completed. Results: The Turkish version of the NPI-C scale showed high internal consistency (Cronbach's α = 0.75) and mostly good interrater reliability. Assessments of validity showed that the NPI-C and corresponding BEHAVE-AD domains were found to be significantly correlated, between 0.925 and 0.195. Moreover, the correlations between NPI-C and MMSE were significant for all domains except the dysphoria, anxiety, and elation/euphoria domains. When we conducted a correlation analysis of NPI-C with IADL, all domains were statistically significantly correlated except aggression, anxiety, elation/euphoria, and dysphoria. Conclusion: The Turkish version of the NPI-C scale was found to be a reliable and valid instrument to assess neuropsychiatric symptoms in Turkish elderly subjects with AD.

The reliability and validity of the Turkish version of theNeuropsychiatric Inventory-Clinician

Background/aim: The Neuropsychiatric Inventory-Clinician (NPI-C) scale is one of the best-known scales for evaluating the behavioral and psychological symptoms of dementia. This study aimed to assess the reliability and validity of the Turkish version of the NPI-C scale in patients with Alzheimer disease (AD). Materials and methods: The NPI-C scale was administered to 125 patients with AD. For reliability, both Cronbach's α and interrater reliability were analyzed. The Behavioral Pathology in Alzheimer's Disease (BEHAVE-AD) scale was applied for validity and, in addition, the Mini Mental State Examination (MMSE), Instrumental Activities of Daily Living (IADL) scale, and Disability Assessment of Dementia (DAD) scale were completed. Results: The Turkish version of the NPI-C scale showed high internal consistency (Cronbach's α = 0.75) and mostly good interrater reliability. Assessments of validity showed that the NPI-C and corresponding BEHAVE-AD domains were found to be significantly correlated, between 0.925 and 0.195. Moreover, the correlations between NPI-C and MMSE were significant for all domains except the dysphoria, anxiety, and elation/euphoria domains. When we conducted a correlation analysis of NPI-C with IADL, all domains were statistically significantly correlated except aggression, anxiety, elation/euphoria, and dysphoria. Conclusion: The Turkish version of the NPI-C scale was found to be a reliable and valid instrument to assess neuropsychiatric symptoms in Turkish elderly subjects with AD.

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Turkish Journal of Medical Sciences-Cover
  • ISSN: 1300-0144
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

Cognitive problems related to vertebrobasilar circulation

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Potential genetic biomarkers in the early diagnosisof Alzheimer disease: APOE and BIN1

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Evaluation of retinal nerve fiber layer thickness in Alzheimer disease usingspectral-domain optical coherence tomography

Alime GÜNEŞ, Seden DEMİRCİ, Levent TÖK, Özlem TÖK, Serpil DEMİRCİ

Forensic medicine evaluation of Alzheimer patients: a series from Ankara, Turkey

MEHMET CAVLAK, RAMAZAN AKÇAN, ALİ RIZA TÜMER, AYSUN BALSEVEN ODABAŞI, AYKUT LALE, MAHMUT ŞERİF YILDIRIM, EYUP RUŞEN HEYBET

Neurodegeneration in ocular and central nervous systems: optical coherence tomography study in normal-tension glaucoma and Alzheimer disease*

Muhsin ERASLAN, Eren ÇERMAN, Osman ÇEKİÇ, Sevcan BALCI, Volkan DERİCİOĞLU, Özlem ŞAHİN, Devran SÜER, Biman CHABOU, Emine Neşe Tuncer ELMACI

Effect of Capparis spinosa L. on cognitive impairment induced by D-galactosein mice via inhibition of oxidative stress

Nergiz Hacer TURGUT, Haki KARA, Emre ARSLANBAŞ, Derya Güliz MERT, Bektaş TEPE, Hüseyin GÜNGÖR

The value of FDG-PET/CT by using 3-dimensional stereotactic surface projection software analysis in the differential diagnosis of dementia

Esra ARSLAN, Özgül EKMEKÇİOĞLU, Fatma Arzu GÖRTAN, Zeynep Funda Engin AKCAN, Melih Engin ERKAN, Haci Murat EMÜL, Metin HALAÇ, Tevfik Fikret ÇERMİK, Kerim SÖNMEZOĞLU

Malnutrition is associated with dementia severity and geriatricsyndromes in patients with Alzheimer disease

Demet YILDIZ, Nilüfer Büyükkoyuncu PEKEL, Ahmet Kasim KILIÇ, Elif Nalan TOLGAY, Fatih TUFAN

A Turkish 3-center study evaluation of serum folic acid and vitamin B12 levels in Alzheimer disease

Nuriye Nuray ULUSU, Gökhan YILMAZ, Zübeyde ERBAYRAKTAR, Ahmet Turan EVLİCE, Sevgi ARAS, Görsev YENER, Aslihan AVCI

Alzheimer disease, inflammation, and novel inflammatory marker: resistin

MUHAMMET CEMAL KIZILARSLANOĞLU, ÖZGÜR KARA, YUSUF YEŞİL, MEHMET EMİN KUYUMCU, ZEYNEL ABİDİN ÖZTÜRK, MUSTAFA CANKURTARAN, SAMED RAHATLI, NAGEHAN PAKAŞTİÇALI, ESAT ÇINAR, MELTEM GÜLHAN HALİL, BURÇİN ŞENER, EYLEM ŞAHİN CANKURTARAN, SERVET ARIOĞUL