The reliability and validity of the Turkish version of theNeuropsychiatric Inventory-Clinician

Background/aim: The Neuropsychiatric Inventory-Clinician (NPI-C) scale is one of the best-known scales for evaluating the behavioral and psychological symptoms of dementia. This study aimed to assess the reliability and validity of the Turkish version of the NPI-C scale in patients with Alzheimer disease (AD). Materials and methods: The NPI-C scale was administered to 125 patients with AD. For reliability, both Cronbach's α and interrater reliability were analyzed. The Behavioral Pathology in Alzheimer's Disease (BEHAVE-AD) scale was applied for validity and, in addition, the Mini Mental State Examination (MMSE), Instrumental Activities of Daily Living (IADL) scale, and Disability Assessment of Dementia (DAD) scale were completed. Results: The Turkish version of the NPI-C scale showed high internal consistency (Cronbach's α = 0.75) and mostly good interrater reliability. Assessments of validity showed that the NPI-C and corresponding BEHAVE-AD domains were found to be significantly correlated, between 0.925 and 0.195. Moreover, the correlations between NPI-C and MMSE were significant for all domains except the dysphoria, anxiety, and elation/euphoria domains. When we conducted a correlation analysis of NPI-C with IADL, all domains were statistically significantly correlated except aggression, anxiety, elation/euphoria, and dysphoria. Conclusion: The Turkish version of the NPI-C scale was found to be a reliable and valid instrument to assess neuropsychiatric symptoms in Turkish elderly subjects with AD.

The reliability and validity of the Turkish version of theNeuropsychiatric Inventory-Clinician

Background/aim: The Neuropsychiatric Inventory-Clinician (NPI-C) scale is one of the best-known scales for evaluating the behavioral and psychological symptoms of dementia. This study aimed to assess the reliability and validity of the Turkish version of the NPI-C scale in patients with Alzheimer disease (AD). Materials and methods: The NPI-C scale was administered to 125 patients with AD. For reliability, both Cronbach's α and interrater reliability were analyzed. The Behavioral Pathology in Alzheimer's Disease (BEHAVE-AD) scale was applied for validity and, in addition, the Mini Mental State Examination (MMSE), Instrumental Activities of Daily Living (IADL) scale, and Disability Assessment of Dementia (DAD) scale were completed. Results: The Turkish version of the NPI-C scale showed high internal consistency (Cronbach's α = 0.75) and mostly good interrater reliability. Assessments of validity showed that the NPI-C and corresponding BEHAVE-AD domains were found to be significantly correlated, between 0.925 and 0.195. Moreover, the correlations between NPI-C and MMSE were significant for all domains except the dysphoria, anxiety, and elation/euphoria domains. When we conducted a correlation analysis of NPI-C with IADL, all domains were statistically significantly correlated except aggression, anxiety, elation/euphoria, and dysphoria. Conclusion: The Turkish version of the NPI-C scale was found to be a reliable and valid instrument to assess neuropsychiatric symptoms in Turkish elderly subjects with AD.

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Turkish Journal of Medical Sciences-Cover
  • ISSN: 1300-0144
  • Yayın Aralığı: 6
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

Age-related macular degeneration and Alzheimer disease

EREN ÇERMAN, MUHSİN ERASLAN, OSMAN ÇEKİÇ

Cognitive problems related to vertebrobasilar circulation

Abdulkadir KOÇER

Molecular docking and ex vivo and in vitro anticholinesterase activity studies ofSalvia sp. and highlighted rosmarinic acid

Lütfiye Ömür DEMİREZER, Perihan GÜRBÜZ, Emine Pelin Kelicen UĞUR, Mine BODUR, Nadire ÖZENVER, Ayşe UZ, Zühal GÜVENALP

The value of FDG-PET/CT by using 3-dimensional stereotactic surface projection software analysis in the differential diagnosis of dementia

Esra ARSLAN, Özgül EKMEKÇİOĞLU, Fatma Arzu GÖRTAN, Zeynep Funda Engin AKCAN, Melih Engin ERKAN, Haci Murat EMÜL, Metin HALAÇ, Tevfik Fikret ÇERMİK, Kerim SÖNMEZOĞLU

Vitamin D status and its association with gradual decline in cognitive function

YUSUF YEŞİL, MEHMET EMİN KUYUMCU, ÖZGÜR KARA, BURÇİN HALAÇLI, SEZGİN ETGÜL, MUHAMMET CEMAL KIZILARSLANOĞLU, BURCU BALAM YAVUZ, MÜNEVVER ÖZCAN, MELTEM GÜLHAN HALİL, EYLEM ŞAHİN CANKURTARAN, MUSTAFA CANKURTARAN, SERVET ARIOĞUL

Impaired cognitive performance and hippocampal atrophy in Parkinson disease

DEMET YILDIZ, SEVDA ERER, MEHMET ZARİFOĞLU, BAHATTİN HAKYEMEZ, MUSTAFA BAKAR, NECDET KARLI, ZEYNEP NİGAR VARLIBAŞ, FATİH TUFAN

Potential genetic biomarkers in the early diagnosisof Alzheimer disease: APOE and BIN1

GÜLHAN KAYA, ESRA GÜNDÜZ, MURADİYE ACAR, Ömer Faruk HATİPOĞLU, BURCU ACAR, ATİLLA İLHAN, MEHMET GÜNDÜZ

A comparison of hair and serum trace elements in patients with Alzheimer disease and healthy participants

EMİNE RABİA KOÇ, ATİLLA İLHAN, ZÜBEYDE AYTÜRK, BURCU ACAR, MUKADDES GÜRLER, AYNUR ALTUNTAŞ, MUSTAFA KARAPİRLİ, ABDURRAHMAN SAİD BODUR

Forensic medicine evaluation of Alzheimer patients: a series from Ankara, Turkey

MEHMET CAVLAK, RAMAZAN AKÇAN, ALİ RIZA TÜMER, AYSUN BALSEVEN ODABAŞI, AYKUT LALE, MAHMUT ŞERİF YILDIRIM, EYUP RUŞEN HEYBET

Alzheimer disease and anesthesia

GÖZDE İNAN, ZERRİN ÖZKÖSE ŞATIRLAR