Age-related macular degeneration and Alzheimer disease

This review highlight the similarities in the pathogenesis between Alzheimer disease and age-related macular degeneration. All studies published between 1990 and 2014 were reviewed to identify the common pathological pathways. Alzheimer disease and age-related macular degeneration share common features such as vitronectin and amyloid-β accumulation, increased oxidative stress, and apolipoprotein and complement activation pathways, which are reviewed as histologic and immunologic common features.
Anahtar Kelimeler:

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Age-related macular degeneration and Alzheimer disease

This review highlight the similarities in the pathogenesis between Alzheimer disease and age-related macular degeneration. All studies published between 1990 and 2014 were reviewed to identify the common pathological pathways. Alzheimer disease and age-related macular degeneration share common features such as vitronectin and amyloid-β accumulation, increased oxidative stress, and apolipoprotein and complement activation pathways, which are reviewed as histologic and immunologic common features.

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Turkish Journal of Medical Sciences-Cover
  • ISSN: 1300-0144
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

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Potential genetic biomarkers in the early diagnosisof Alzheimer disease: APOE and BIN1

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Age-related macular degeneration and Alzheimer disease

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Effect of Capparis spinosa L. on cognitive impairment induced by D-galactosein mice via inhibition of oxidative stress

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The connection between MCI and Alzheimer disease: neurocognitive clues

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Why is Alzheimer disease confused with other dementias?

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Preface - Special Issue on: Alzheimer Disease: From Bench to Bedside'

MARK S KINDY, ÖMER AKYOL, KUMAR SAMBAMURTI

Is Alzheimer disease related to age-related macular degeneration?

Seden DEMİRCİ, Alime GÜNEŞ, Kadir DEMİRCİ, Serpil DEMİRCİ, Levent TÖK, Özlem TÖK

Neurodegeneration in ocular and central nervous systems: optical coherence tomography study in normal-tension glaucoma and Alzheimer disease*

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