Teoman ERDEM, Fatih AKÇAY, İrfan ALTUNTAŞ, Necmettin AKDENİZ

Lipid peroxidation in Behçet's disease in active and remission periods

Recent few studies revealed that increased levels of oxygen free radicals might play a role in tissue damage. There are some studies in the literature proposing that increased levels of oxygen radicals might play a role in tissue damage, as also seen in Behçet's disease (BD). The aim of the present study was to measure plasma malondialde-hyde (MDA) (as an index of lipid peroxida-tion) levels in 23 patients with BD (13 men, 10 women with a mean age of 34.5 ± .2 years) both in active and in remission periods. Twenty-one healthy volunteers (11 men, 10 women) formed as the control group. It was found that mean plasma MDA levels were significantly higher both in the active (11.147 ± 2.452 nmol/mL) and remission (8.056 ± 1.916 nmol/mL) periods in patients with BD than in the controls (4.978 ± 1.431 nmol/mL) (p

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