Rana IŞIK, Füsun ALATAŞ, Muzaffer METİNTAŞ, Necla ÖZDEMİR, Sinan ERGİNEL, Özkan ALATAŞ

108114

The Effects of Smoking on Glutathione Levels in Bronchoalveolar Lavage Fluid

Cigarette smoke contains high concentrations of oxidants and reactive oxygen species. The aim of this study was to evaluate the effect of long-term cigarette smoking on glutathione (GSH) levels in bronchoalveolar lavage (BAL) fluid. Nineteen current cigarette smokers and seven healthy nonsmoking volunteers were included in the study. BAL was performed by infusion of five sequential 20 ml aliquots and each aliquot was immediately aspirated. The levels of GSH were determined in BAL fluids. The epithelial lining fluid volume was calculated by the ratio of urea concentration in BAL fluid to that in serum. Lower GSH levels were observed in the BAL fluid of current smokers than in that of nonsmokers (8.28 ± 0.78, 12.74 ± 1.09 µM respectively, p
Anahtar Kelimeler:

Bronchoalveolar lavage, Chronic obstructive pulmonary disease, Glutathione, Smoking.

The Effects of Smoking on Glutathione Levels in Bronchoalveolar Lavage Fluid

Cigarette smoke contains high concentrations of oxidants and reactive oxygen species. The aim of this study was to evaluate the effect of long-term cigarette smoking on glutathione (GSH) levels in bronchoalveolar lavage (BAL) fluid. Nineteen current cigarette smokers and seven healthy nonsmoking volunteers were included in the study. BAL was performed by infusion of five sequential 20 ml aliquots and each aliquot was immediately aspirated. The levels of GSH were determined in BAL fluids. The epithelial lining fluid volume was calculated by the ratio of urea concentration in BAL fluid to that in serum. Lower GSH levels were observed in the BAL fluid of current smokers than in that of nonsmokers (8.28 ± 0.78, 12.74 ± 1.09 µM respectively, p
Keywords:

Bronchoalveolar lavage, Chronic obstructive pulmonary disease, Glutathione, Smoking.,

PDF
Turkish Journal of Medical Sciences-Cover
  • ISSN: 1300-0144
  • Yayın Aralığı: 6
  • Yayıncı: TÜBİTAK
Arşiv
Sayıdaki Diğer Makaleler

Tooth pain and numb chin as the initial presentation of systemic malignancy

Sedat ÇETİNER, Cansu ALPASLAN, Nadir GÜNGÖR, Ülker KOÇAK

An Immunohistochemical Study of Gastric Neuroendocrine Tumors: Expression of Proliferating Cell Nuclear Antigen and P53 Oncoprotein

Gülen DOĞUSOY

A Comparison of the Effectiveness of Sublingual Losartan, Sublingual Captopril and Sublingual Nifedipine in Hypertensive Urgency

Yüksel GÖKEL, Saime PAYDAS, Salim SATAR

A Combined Variation of the Arteries and The Nerve in a Leg

Zeliha KURTOĞLU, M. Haluk ULUUTKU

Evaluation of Ocular Surface Changes Using Impression Cytology in Acne Vulgaris Patients

Banu N. ALP, Levent KARABAŞ, Haluk TALU, Ahmet KAUR, Nilgün BİLEN, Ateş YANYALI

Effect of etidronate on urinary calcium / creatinin ratio in postmenopausal women: A prospective, randomized, placebo controlled study

Şenol KÜÇÜK, Ruşen ATMACA, Remzi GÖKDENİZ, Ömür TAŞKIN, İsmail URYAN, Ali BUHUR

The Effects of Smoking on Glutathione Levels in Bronchoalveolar Lavage Fluid

Rana IŞIK, Füsun ALATAŞ, Muzaffer METİNTAŞ, Necla ÖZDEMİR, Sinan ERGİNEL, Özkan ALATAŞ

Action of Aspirin on Acetylcholine-Stimulated Tear Secretion in Rats

Zerrin KAPICIOĞLU, İ. Nuri KALYONCU, Gamze ÇAN

Lipid Peroxidation in Behçet's Disease in Active and Remission Periods

Teoman ERDEM

An immunohistohemical study of gastric neuroendocrine tumors: Expression of proliferating cell nuclear antigen and P53 oncoprotein

Gülen DOĞUSOY, Süha GÖKSEL, Selda GÖÇENER, Haydar DURAK, Işıl PAKİŞ, Gökhan ERSOY