A rare presentation of brucellosis: polyradiculopathy and peripheral neuritis
To present 8 patients with polyradiculopathy or polyradiculoneuritis caused by brucellosis. Polyradiculopathy or polyradiculoneuritis are occasional neurological involvements of brucellosis. Materials and methods: The diagnosis was made with clinical, serological and/or cerebrospinal fluid, and electromyographic examinations. Results: All of the patients except one improved quickly after specific antimicrobial treatment. Furthermore, electrophysiological examinations revealed normal findings in 6 patients. Conclusion: This clinical form of brucellosis is mostly reversible if it is diagnosed earlier and treated effectively.
A rare presentation of brucellosis: polyradiculopathy and peripheral neuritis
To present 8 patients with polyradiculopathy or polyradiculoneuritis caused by brucellosis. Polyradiculopathy or polyradiculoneuritis are occasional neurological involvements of brucellosis. Materials and methods: The diagnosis was made with clinical, serological and/or cerebrospinal fluid, and electromyographic examinations. Results: All of the patients except one improved quickly after specific antimicrobial treatment. Furthermore, electrophysiological examinations revealed normal findings in 6 patients. Conclusion: This clinical form of brucellosis is mostly reversible if it is diagnosed earlier and treated effectively.
___
- Young EJ. Brucella species. In: Mandell GL, Bennett JE, Dolin R, editors. Principles and practice of infectious diseases. 6th ed. Philadelphia (PA): Churchill Livingstone; 2005. p.2669-74. 2. Shakir RA. Neurobrucellosis. Postgrad Med J 1986; 62: 1077-9.
- Coskun O, Ertem TG, Ergun U, Kutlu G, Tulek N, Inan LE. Evaluation of brainstem auditory potential in brucellosis patients with and without neurological involvement. Intern J Neuroscience 2005; 15: 717-23. 4. Omar FZ, Zuberi S, Minns RA. Neurobrucellosis in childhood: six new cases and a review of the literature. Dev Med Child Neurol 1997; 39: 762-5.
- Gul HC, Erdem H, Bek S. Overview of neurobrucellosis: a pooled analysis of 187 cases. Int J Infect Dis 2009; 13: e339-43.
- Oh SJ. Clinical electromyography: Nerve conduction studies. 2nd ed. Baltimore: Williams & Wilkins; 1993.
- Kochar DK, Agarwal N, Jain N, Sharma BV, Rastogi A, Meena CB. Clinical profi le of neurobrucellosis—a report on 12 cases from Bikaner (north-west India). J Assoc Physicians India 2000; 48: 376-80.
- Vajramani GV, Nagmoti MB, Patil CS. Neurobrucellosis presenting as an intra-medullary spinal cord abscess. Ann Clin Microbiol Antimicrob 2005; 4: 14. 9. Al Deeb SM, Yaqub BA, Sharif HS, Phadge JG. Neurobrucellosis: clinical characteristics, diagnosis, and outcome. Neurology 1989; 39: 498-501.
- Shakir RA, Al Din ASN, Araj GF, Lulu AR, Mousa AR, Saadah MA. Clinical categories of neurobrucellosis: a case report on 19 cases. Brain 1987; 110: 213-23.
- Goktepe AS, Alaca R, Mohur H, Coskun U. Neurobrucellosis and a demonstration of its involvement in spinal roots via magnetic resonance imaging. Spinal Cord 2003; 41: 574-6.
- Özerbil ÖM, Ural O, Topatan Hİ, Erongun U. Lumbar spinal root compression caused by Brucella granuloma. Spine 1998; 23: 491-3.
- Bahemuka M, Shemena AR, Panayiotopoulos CP, Al-Aska AK, Obeid T, Daif AK. Neurological syndromes of brucellosis. J Neurol Neurosurg Psychiatry 1988; 51: 1017-21.
- Hesseling AC, Marais BJ, Cotton MF. A child with neurobrucellosis. Ann Trop Paediatr 2003; 23: 145-8.
- Pascual J, Combarros O, Polo JM, Berciano J. Localized CNS brucellosis: report of 7 cases. Acta Neurol Scand 1988; 78: 282- 9.
- Bashir R, Al-Kawi MZ, Harder EJ. Nervous system brucellosis: diagnosis and treatment. Neurology 1985; 35: 1576-81.
- Reitman CA, Watters WC. Spinal brucellosis: case report in the United States. Spine 2002; 27: E250-2.
- Yetkin MA, Bulut C, Erdinc FS, Oral B, Tulek N. Evaluation of the clinical presentations in neurobrucellosis. Int J Infect Dis 2006; 10: 446-52.
- Demiraslan H, Metan G, Meşe EA, Yildiz O, Aygen B, Sumerkan B et al. Neurobrucellosis: an evaluation of a rare presentation of brucellosis from a tertiary care centre in Central Anatolia, Turkey. Trop Doct 2009; 39: 233-5.
- Ranjbar M, Rezaiee AA, Hashemi SH, Mehdipour S. Neurobrucellosis: report of a rare disease in 20 Iranian patients referred to a tertiary hospital. East Mediterr Health J 2009; 15: 143-8.
- Gul HC, Erdem H, Gorenek L, Ozdag MF, Kalpakci Y, Avci IY et al. Management of neurobrucellosis: an assessment of 11 cases. Intern Med 2008; 47: 995-1001.
- Kutlu G, Ertem GT, Coskun O, Ergun U, Gomceli YB, Tulek N et al. Brucella: A cause of peripheral neuropathy. Eur Neurol 2009; 61: 33-8.
- Mousa AM, Araj GF, Koshy TS, Muhtaseb SA, Al-Mudallal DS. Neurological complications of brucella spondylitis. Acta Neurol Scand 1990; 81: 16-23.
- Ulas UH, Hamamcioglu K, Eroglu E, Odabasi Z, Alanoglu E, Demirkaya S et al. Paraplegia associated with brucellosis involving the anterior lumbrosacral nerve roots. J Peripher Nerv Syst 2003; 8: 8-12.
- Bucher A, Gaustad P, Pape E . Chronic neurobrucellosis due to Brucella melitensis. Scand J Infect Dis 1990; 22: 223-6.
- Tanyel E, Coban AY, Koruk ST, Simsek H, Hepsert S, Cirit OS. Actual antibiotic resistance pattern of Brucella melitensis in central Anatolia. An update from an endemic region. Saudi Med J 2007; 28: 1239-42.
- Baykam N, Esener H, Ergönül Ö, Eren Ş, Çelikbas A, Dokuzoğuz B. In vitro antimicrobial susceptibility of Brucella species. Int J Antimicrob Agents 2004; 23: 405-7.
- Bodur H, Erbay A, Akinci E, Colpan A, Cevik MA, Balaban N. Neurobrucellosis in an endemic area of brucellosis. Scand J Infect Dis 2002; 35: 94-7.