A comparison of the eff ects of intrathecal ropivacaine and bupivacaine during cesarean section

Amaç: Sezaryenlerde intratekal izobarik ropivakain ve bupivakain ile opioidlerin motor ve duyusal blok özelliklerine etkilerinin karşılaştırılması amaçlandı. Yöntem ve gereç: Elli iki gebe spinal anestezi için 25 μg fentanil + 100 μg morfi n ile % 0,5 izobarik bupivakain 10 mg (Grup B) veya % 0,75 izobarik ropivakain 15 mg (Grup R) vermek üzere rastgele iki gruba ayrıldı. Duyusal ve motor blok özellikleri kaydedildi. Bulgular: T6’da duyusal blok elde etme zamanı Grup B’de Grup R’den anlamlı olarak hızlıydı (2,7 ± 1,8 ile 4,2 ± 2,5 dk). Maksimum duyusal blok seviyesine ulaşma süresi Grup B’de Grup R’den hızlı bulundu (8,1 ± 4,1 ile 11,6 ± 5,6 dk). Grup B’de T10 ve L1 dermatomlarına gerileme süreleri (118,2 ± 24,2 ile 145,5 ± 28,1 dk, sırasıyla) Grup R’den daha kısaydı (135 ± 32,1 ile 162,5 ± 32,5 dk, sırasıyla). Motor blok süresi Grup B’de Grup R’den daha uzundu (165,8 ± 32,5 ile 135,2 ± 45,7 dk). Sonuç: İntratekal izobarik ropivakain ile opioidler daha uzun duyusal blok ve daha kısa motor blok süresiyle sezaryenler için bupivakainden üstün olabilir.

Sezaryenlerde intratekal ropivakain ve bupivakainin etkilerinin karşılaştırılması

Aim: To compare the eff ects of intrathecal plain bupivacaine or ropivacaine with those of opioids on sensory and motor block characteristics during cesarean section (C/S). Materials and methods: Fift y-two ASA I or II women were randomly allocated into 2 groups to administer either 10 mg of 0.5% plain bupivacaine (Group B), or 15 mg of 0.75% plain ropivacaine (Group R) with 25 μg fentanyl and 100 μg morphine for spinal anesthesia. Characteristics of the sensory and motor block were recorded. Results: Th e time to achieve sensory block at T6 was signifi cantly faster in Group B than in Group R (2.7 ± 1.8 min vs. 4.2 ± 2.5 min). Th e time to reach maximum sensory block was signifi cantly faster in Group B than in Group R (8.1 ± 4.1 min vs. 11.6 ± 5.6 min). Th e times of sensory block regression to T10 and L1 dermatomes were signifi cantly shorter in Group B (118.2 ± 24.2 min and 145.5 ± 28.1 min, respectively) than in Group R (135 ± 32.1 min and 162.5 ± 32.5 min, respectively). Motor block duration was significantly longer in Group B than in Group R (165.8 ± 32.5 min vs. 135.2 ± 45.7 min). Conclusion: Intrathecal plain ropivacaine with opioids might be superior to bupivacaine in terms of a longer sensory block, and a shorter motor block duration for C/S.

___

  • 1. Tsen L. Anesthesia for Cesarean Delivery. In: Chestnut DH, Polley LS, Tsen LC, Wong CA, editors. Chestnut’s Obstetric Anesthesia Principals and Practice. 4th ed. Philadelphia: Mosby Elsevier; 2009. p. 521-74.
  • 2. Ogun CO, Kirgiz EN, Duman A, Okesli S, Akyurek C. Comparison of intrathecal isobaric bupivacaine-morphine and ropivacaine-morphine for Caesarean delivery. Br J Anaesth 2003; 90: 659-64.
  • 3. Khaw KS, Ngan Kee WD, Wong M, Ng F, Lee A. Spinal ropivacaine for cesarean section: a dose-fi nding study. Anesthesiology 2001; 95: 1346-50.
  • 4. Gautier P, Kock MD, Huberty L, Demir T, Izydorczic M, Vanderick B. Comparison of the eff ects of intrathecal ropivacaine, levobupivacaine, and bupivacaine for caesarean section. Br J Anaesth 2003; 91: 684-9.
  • 5. Carvalho B, Durbin M, Drover DR, Cohen SE, Ginosar Y, Riley ET. Th e ED50 and ED95 of intrathecal isobaric bupivacaine with opioids for cesarean delivery. Anesthesiology 2005; 103: 606-12.
  • 6. Danelli G, Fanelli G, Berti M, Cornini A,Lacava L, Nuzzi M, Fanelli A. Spinal ropivacaine or bupivacaine for cesarean delivery: a prospective, randomized, double-blind comparison. Reg Anesth Pain Med 2004; 29: 221-6.
  • 7. Kallio H, Snall ET, Kero MP, Rosenberg PH. A comparison of intrathecal plain solutions containing ropivacaine 20 or 15 mg versus bupivacaine 10 mg. Anesth Analg 2004; 99: 713-7.
  • 8. Malinovsky JM, Charles F, Kick O, Lepage JY, Malinge M, Cozian A, Bouchet O, Pinaud M. Intrathecal anesthesia: Ropivacaine versus bupivacaine. Anesth Analg 2000; 91; 1457- 60.
  • 9. Polley LS, Columb MO, Naughton NN, Wagner DS, Van de Ven CJ. Relative analgesic potencies of ropivacaine and bupivacaine for epidural analgesia in labor: implications for theurapeutic indexes. Anesthesiology 1999; 99: 944-50.
  • 10. Camorcia M, Capogna G, Lyons G C, Columb MO. Th e relative motor block potencies of intrathecal ropivacaine: Eff ects of concentration. Anesth Analg 2004; 98: 1779- 82.
  • 11. Camorcia M, Capogna G, Berritta C, Columb MO. Th e relative potencies for motor block aft er intrathecal ropivacaine, levobupivacaine, and bupivacaine. Anesth Analg 2007; 104: 904-7.
Turkish Journal of Medical Sciences-Cover
  • ISSN: 1300-0144
  • Yayın Aralığı: 6
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

Effects of plasma lipids and smoking on cognitive function

Adem ÖZKARA, Atilla İLHAN, Burcu YANIK, M. Ramazan YİĞİTOĞLU, Erkan KIBRISLI, İrfan ŞENCAN, Oğuz TEKİN, Metin CANBAL

A pattern of lymphadenopathies seen in a tertiary care hospital in Lahore, Pakistan

Waqas SAMI, Sobia Sadiq NASEEM, Abdul H.NAGI, Saira BİLAL, Maham AKHLAQ, Nausheen HENNA, Muhammad ASHRAF

Th e role of red cell distribution width as a marker in infl ammatory bowel disease

Adnan TAŞ, İbrahim Koral ÖNAL, Aysel ÜLKER, Bilge TUNÇ, Mehmet ARHAN, İsmail Hakkı KALKAN, Mevlüt KURT, Yasemin ÖZİN

In vitro eff ects of some drugs on human erythrocyte glutathione reductase

Mehmet ÇİFTÇİ, Murat ŞENTÜRK, Fatma Betül ÖZGERİŞ, Ebru AKKEMİK, Pınar TAŞER

Serum paraoxonase and arylesterase activities in iron deficiency anemia during pregnancy

Abdullah TAŞKIN, Hakim ÇELİK, Harun TOY, Gakan CAMUZCUOĞLU, Aysun CAMUZCUOĞLU, Mehmet VURAL

Immunomodulatory role of leptin treatment in experimental sepsis caused by gram negative bacteria

Özlem ALICI, Havva ŞAHİN KAVAKLI, Cemile KOCA

A determination of the factors that aff ect the level of pediatric nurses’ liking of children

Yurdagül ERDEM, Veli DUYAN

A comparison of the eff ects of intrathecal ropivacaine and bupivacaine during cesarean section

Berrin GÜNAYDIN, Nuray CAMGÖZ ERYILMAZ

Distribution of coronary artery risk factors: a regional analysis

Hüseyin Avni UYDU, Mehtap ATAK, Aytun ÇANGA, Ahmet TEMİZ, Ömer ŞATIROĞLU, Zakir KARADAĞ, Yavuz UĞURLU, Yüksel ÇİÇEK, Mehmet BOSTAN, Engin BOZKURT

Investigation of toxin genes in Staphylococcus aureus strains isolated in Mustafa Kemal University Hospital

Cemil DEMİR, Nizami DURAN, Burçin ÖZER, Özkan ASLANTAŞ, Sabahattin OCAK