Fatma GÜMÜŞER, Merve ALTINKAYNAK, Dilek Yildiz SEVGİ, Özlem Altuntaş AYDIN, Bilgül METE, Alper GÜNDÜZ, Hayat Kumbasar KARAOSMANOĞLU, Sibel BOLUKÇU, Ömer Fehmi TABAK, Mustafa Haluk VAHABOĞLU

Human immunodeficiency virus and tuberculosis coinfection: clinical features and predictors of mortality

ISSN: 1300-0144
Yayın Aralığı: 6
Yayıncı: TÜBİTAK

Background/aim: This study was undertaken to identify subjects with human immunodeficiency virus and tuberculosis (HIV/TB) coinfection in a group of HIV-positive patients followed at five different healthcare centers, and to determine the demographic and clinical characteristics of these subjects as well as the predictors of mortality. Materials and methods: A database search for subjects with TB coinfection was performed among 1475 HIV-positive adult patients and a total of 66 individuals were identified with HIV/TB coinfection. Results: There were 66 patients (4.5%) with TB coinfection. Twenty-one percent (n = 14) of the patients with TB coinfection died during the study period and these patients had significantly lower baseline CD4 counts at the time of TB diagnosis (P = 0.005). None of the patients with CD4 count of ≥200 cells/mm3 died during follow-up and a low CD4 count at the time of TB diagnosis ( Keywords: Human immunodeficiency virus, tuberculosis, coinfection, mortality Full Text: PDF

Keywords: