The present study was conducted to investigate the effect of lead (Pb) on the growth hormone (GH) and plasma cortisollevel of common carp, Labeo rohita. One hundred Labeo rohita were divided in two equal groups; control and treated.Treated fishes were exposed to 1.4mg/l of lead acetate (1.9% lead concentration i,e., LC50) at the interval of 72 hours for aperiod of five weeks. Blood was collected from the caudal vein of fish from both treated and control groups, after weekinterval. Mean body weight of treated group decreased significantly as compared to the control group (P
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Abbas, S., & Javed, M. (2016). Growth performance of metals mixture stressed fish in Earthen Ponds. Pakistan Journal of Zoology, 48(3), 845-851.
Amin, A., Ramachandra Naik, A.T., Priyadarshini, N., Nayak, H., & Sree, C.S. (2017). Toxic effect of heavy metal lead on oxygen consumption of rohu (Labeo rohita) fingerlings. Biochemical and Cellular Archives, 17(1), 225-228.
Anbu, K. (2014). Primary and secondary stress responses in Indian major carps when exposed to heavy metals. International Journal of Biotechnology, 2(8), 7-12.
Aoyama, K., & Nakaki, T. (2013). Impaired glutathione synthesis in neurodegeneration. International Journal of Molecular Science, 14, 21021-21044. http://doi.org/10.3390/ijms141021021
Bellinger, D.C. (2005). Teratogen updates: Pb and pregnancy. Birth Defects Research Part A: Clinical and Molecular Teratology, 73(6), 409-420. http://doi.org/10.1002/bdra.20127
Bellinger, D.C. (2008). Very low lead exposure and children neurodevelopment. Current Opinion in Pediatrics, 20(1), 172-177. http://doi.org/10.1097/MOP.0b013e3282f4f97b
Beveridge, M.C.M., Thilsted, S.H., Phillips, M.J., Metian, M., Troell M., & Hall, S.J. (2013). Meeting the food and nutrition needs of the poor: the role of fish and the opportunities and challenges emerging from the rise of aquaculturea. Journal of Fish Biology, 83, 1067– 1084. https://doi.org/10.1111/jfb.12187.
El-Shebly, A.A. (2009). Protection of Nile Tilapia (Oreochromis niloticus) from lead pollution and enhancement of its growth by α- tocopherol vitamin E. Research Journal of Fisheries and Hydrobiology, 4(1), 17-21.
Firidin, G. (2016). The effect of Pb and Pb + Zn mixture on protein and Pb levels of Tilapia fish (Oreochromis niloticus). Eco Life Science, 11(4), 19-27. http://doi.org/10.12739/NWSA.2016.11.4.5A0079
Franco, R., Schoneveld, O.J., Pappa, A., & Panayiotidis, M.I. (2007). The central role of glutathione in the pathophysiology of human diseases. Archives of Physiology and Biochemistry, 113(4-5), 234-258.
Gagan, F., Deepash, G., & Archana, T. (2012). Toxicity of lead: A review with recent updates. Journal of Interdisciplinary Toxicology, 5(2), 47-58. http://doi.org/10.2478/v10102-012-0009-2
Gagnon, A., Jumarie, C., & Hontela, A. (2006). Effects of Cu on plasma cortisol and cortisol secretion by adrenocortical cells of rainbow trout (Oncorhynchus mykiss). Aquatic Toxicology, 78(1), 59–65. https://doi.org/10.1016/j.aquatox.2006.02.004
Gharedaashi, E., Nekoubin, H., Asgharimoghadam, A., Imanpour, M.R., & Taghizade, V. (2012). Effect of lead nitrate on survival rate and chronic exposure on growth performance of grass carp (Ctenopharyngodon idella). Journal of Toxicology and Environmental Health Sciences, 4(10), 171-174.
Giguere, A., Campbell, L., Hare, D.G., McDonald, G., & Rasmussen, L. (2004). Influence of lake chemistry and fish age on cadmium, copper and zinc concentrations in various organs of indigenous yellow perch (Perca flavescens). Canadian Journal of Fisheries and Aquatic Sciences, 61(9), 1702–1716. https://doi.org/10.1139/f04-100
Gill, S., Tewarz, H., & Pande, J. (1991). Effects of waterborne Pb and copper on the peripheral blood in the rosy barb, Barbus (Puntius) conchonius Hamilton. The Bulletin of Environmental Contamination and Toxicology, 46(6), 606-612. https://doi.org/10.1007/BF01688206
Halver, J.E. (1989). Formulating practical diet for fish. Journal of Fisheries Research Board, Canada, 33, 1032-1039.
Hontela, A. (2005). Adrenal toxicology: environmental pollutants and the HPI axis. Biochemistry and Molecular Biology of Fishes, 6, 331-363. https://doi.org/10.1016/S1873-0140(05)80015-3
Hontela, H., Rasmussen, J.B., & Chevaileir, G. (2007). Endocrine response as indicators of sublethal toxic stress in fish from polluted environments. Water Pollution Research Journal of Canada, 28(4), 767- 780.
Javed, M. (2015). Chronic dual exposure (waterborne + dietary) effects of cadmium, zinc and copper on growth and their bioaccumulation in Cirrhina mrigala. Pakistan Veterinary Journal, 35, 143-146.
Javed, M., Abdullah, M., Yaqub, M. (2008). Studies on tissue-specific metal bio-accumulation patterns and differences in sensitivity of fish to water-borne and dietary metals. First annual research report (HEC Project # R & D 803), pp: 1-32.
Kasperczyk, A., Machnik, G., Dobrakowski, M., Sypniewski, D., Birkner, E., & Kasperczyk, S. (2012). Gene expression and activity of antioxidant enzymes in the blood cells of workers who were occupationally exposed to lead. Toxicology, 301(1-3), 79-84. https://doi.org/10.1016/j.tox.2012.07.002
Kirberger, M., Wong, H.C., Jiang, J., & Yang, J.J. (2013). Metal toxicity and opportunistic binding of Pb2+ in proteins. Journal of Inorganic Biochemistry, 125(2013), 40-49. https://doi.org/10.1016/j.jinorgbio.2013.04.002
Kumar, P., Prasad, Y., Patra, A.K., Rajan, R., & Swarup, D. (2009). Levels of cadmium and Pb in tissues of freshwater fish and chicken in Western UP. The Bulletin of Environmental Contamination and Toxicology, 79(4), 396-400. https://doi.org/ 10.1007/s00128-007-9263-y.
Marchi, B., Burlando, B., Moore, M.N., & Viarengo, A. (2004). Mercury and copper induced lysosomal membrane destabilization depends on [Ca2+] independent phospholipase A2 activation. Aquatic Toxicology, 66(2), 197–204. https://doi.org/10.1016/j.aquatox.2003.09.003
Mousa, S.A., & Mousa, M.A. (1999). Immunocytochemical and histological studies on the hypophyseal-gonadal system in the freshwater Nile tilapia, Oreochromis niloticus (L.), during sexual maturation and spawning in different habitats. Journal of Experimental Zoology, 284(30), 343–354.
Nair, J., & Ajit, S.S. (2008). The role of the glutamatergic system in posttraumatic stress disorder. CNS Spectrum, 13(7), 585-591.
Orire, A.M., & Sadiku, S.O.E. (2011). Protein sparing effects of lipid in the practical diets of Oreochromis niloticus (Nile Tilapia). Nigerian Journal of Basic and Applied Science, 19, 142-150.
Orire, A.M., Omotoyinbo, S.O., & Sadiku, S.O.E. (2013). The growth and body composition of Clarias gariepinus fingerlings fed combined different sources of lipid. Journal of Aquaculture Research and Development, 4(4), 1-5. http://doi.org/10.4172/2155-9546.1000182
Paul, N., Chakraborty, S., & Sengupta, M. (2014). Lead toxicity on non-specific immune mechanisms of freshwater fish Channa punctatus. Aquatic Toxicology, 152, 105-12. https://doi.org/10.1016/j.aquatox.2014.03.017
Ramesh, M., Saravanan, M., & Kavitha, C. (2009). Hormonal responses of the fish, Cyprinus carpio, to environmental lead exposure. African Journal of Biotechnology, 17(1), 4154- 4158.
Ramesha, A.M., Gupta, T.R.C., Chandrakanth, L., Kumar, K.V., Gangadhara, G., & Udapa, K.S. (2003). Combined toxicity of mercury and cadmium to the common carp (Cyprinus carpio). Environmental Ecology, 15, 194-198.
Royes, J.A.B., & Chapman, F.A. Preparing our own fish feeds. Institute of Food and Agricultural Sciences, University of Florida, Gainesville; 2009.
Shahid, M., Alkahem Al-Balawi, H.F., Al-Misned, F., AlQuraishy, S., & Ahmad, Z. (2014). Tissue metal distribution and risk assessment for important fish species from Saudi Arabia. The Bulletin of Environmental Contamination and Toxicology, 92(1), 61–66. https://doi.org/10.1007/s00128-013-1139-8
Souza-Talarico, J.N., Suchecki, D., Juster, R.P., Plusquellec, P., Barbosa Junior, F., Lupien, S.J. (2017). Lead exposure is related to hypercortisolemic profiles and allostatic load in Brazilian older adults. Environmental Research, 154, 261-268. https://doi.org/10.1016/j.envres.2017.01.012
Stevenson, J.R. & Irz, Z. (2009). Is aquaculture development an effective tool for poverty alleviation? A review of theory and evidence. Cahiers Agricultures, 18(2-3), 292-299. https://doi.org/10.1684/agr.2009.0286
Sudagar, M., & Hajibeglou, A. (2010). Effect of plant extract supplemented diets on immunity and resistance to Aeromonas hydrophila in common carp (Cyprinus carpio). Agricutural Journal, 5(2), 119- 127. https://doi.org/10.3923/aj.2010.119.127
Vosyliene, M.Z., Kazlauskiene, N., & Svecevicius, G. (2003). Effect of a heavy metal model mixture on biological parameters of rainbow trout (Oncorhynchus mykiss). Environmental Science Pollution Research International, 10(7), 103–107.