Alterations of Growth Performance and Blood Chemistry in Nile Tilapia (Oreochromis Nuoticus) Affected by Copper Sulfate in Long-Term Exposure

Bu çalışmamızın amacı bakır sülfatın (CuSO4.(5H2O)) Nile Tilapia (Oreochromis niloticus) üzerindeki etkilerini belirlemektir. Bakır sülfatın Nile tilapia üzerindeki medyan (LC50) ve minimum (LC1O) ölümcül konsantrasyonları akut testlerle belirlenmiştir. Bakır sülfatın 48, 72 ve 96 saatlerdeki LC50 değerleri sırası ile 13,15, 12,95 ve 12,85 mg/L idi. Aynı sürelerde elde edilen LC10 değerleri de sırası ile 12, 11 ve 9,5 mg/L idi. 1,5 mg/L bakır sülfat dozunun Nile tilapia'da büyüme, bütüncül klinik görünüm ve kan biyokimyası parametreleri üzerindeki etkileri 35, 65 ve 95 günlük maruziyetler üzerinden değerlendirilmiştir. Kontrol ve bakır sülfat uygulama grupları arasında büyüme oranları arasındaki fark 35, 65 ve 95 gün sonunda anlamlı değildi (P>0,05). 1,5 mg/L'lik bakır sülfat konsantrasyonuna sürekli maruziyet Nile tilapia'da 35, 65 ve 95 günlük süreler sonunda toplam protein, albümin, aspartat aminotransferaz (AST), alanin aminotransferaz (ALT), glikoz (95 günlük gruptaki artış dışında), magnezyum (Mg+²), kalsiyum (Ca+²), demir (Fe+²), potasyum (K+), sodyum (Na+1), klor (Cl-) ve fosfatın serumdaki değerlerini düşürmüştür. Kolesterol, düşük yoğunluklu lipit (LDL), trigliserit, globülin, kreatinin, alkalin fosfataz (ALP), total bilirubin, direkt bilirubin, ürik asit ve üre azotu (BUN) konsantrasyonları bakır sülfata maruz kalan balıkların serumlarında yükselmiştir

Uzun Süre Bakır Sülfata Maruz Kalan Nil Tilapia (Oreochromis Nuoticus) Balığının Büyüme Performansı ve Kan Yapısındaki Değişimle

The objective of this study was to evaluate the effects of copper sulfate (CuSO4(5 H2O)) on the Nile tilapia (Oreochromis niloticus). Median (LC50) and minimum (LC1O) lethal concentrations of copper sulfate on Nile tilapia were determined via acute tests. LC50 values of copper sulfate for the 48th, 72nd and 96th hours were 13.15, 12.95 and 12.85 mg/L, respectively. LC10 values of 12, 11 and 9.5 mg/L were obtained for similar exposure periods (48th, 72nd and 96th hours), respectively. The effects of 1.5 mg/L dose of copper sulfate on growth rate, gross clinical observations and blood biochemical parameters of Nile tilapia were evaluated after 35, 65 and 95 days of exposure periods. The differences of growth rates between control and copper sulfate-exposed groups were not significant (P>0.05) at the end of 35, 65 and 95 days. Continuous exposure of Nile tilapia to 1.5 mg/L concentration of copper sulfate in water solution for three periods (35, 65 and 95 days) decreased the total protein, albumin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), glucose (except the elevation in the exposed group at the end of 95 days period), magnesium (Mg+²), calcium (Ca+²), iron (Fe+²), potassium (K+), sodium (Na+1), chloride (Cl-) and phosphate values in serum. The cholesterol, low density lipid (LDL), triglyceride, globulin, creatinine, alkaline phosphatase (ALP), total bilirubin, direct bilirubin, uric acid and blood urea nitrogen (BUN) concentrations in the serum increased in copper sulfate-exposed fish

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