Önder BİLGE, Ercan TAŞTAN, Murat ÇAP, Ferhat IŞIK, Yusuf Ziya ŞENER, Metin OKŞUL

Kırmızı hücre dağılım genişliği ile dirençli hipertansiyon arasındaki ilişki

Amaç: Eritrosit dağılım genişliğinin (RDW) kardiyovasküler hastalıklarla ilişkili olduğu bilinmektedir. Dirençli hipertansiyonu (DHT) olan hastalarda kardiyovasküler olay riski daha yüksektir. Bu çalışmada RDW ile dirençli hipertansiyon arasındaki ilişkiyi değerlendirmeyi amaçladık. Gereç ve Yöntemler: Bu çalışmaya 24 saatlik ambulatuar kan basıncı ölçümü (AKBÖ) yapılan 69 (%43) dirençli hipertansiyon olmak üzere toplam 157 hasta dahil edildi. AKBÖ'den sonra RDW ve diğer laboratuvar parametreleri ölçüldü. Bulgular: Çalışma popülasyonundaki ortalama yaş 57 ± 11 idi ve hastaların %77'si (121) kadındı. Hastalar kontrollü HT (KHT) ve DHT olarak iki gruba ayrıldı. RDW, KHT grubuna (14.1±1.2) kıyasla DHT grubunda (14.8±1.4) anlamlı olarak daha yüksekti; (p=0,002). Çok değişkenli lojistik regresyon analizi ile RDW (olasılık oranı [OR]: 1.684, %95 Güven Aralığı [GA]: 1.250-2.201 p

Anahtar Kelimeler:

Kırmızı Kan Hücresi Genişliği, Hipertansiyon, Dirençli Hipertansiyon, Kontrollü Hiper-tansiyon, Ayaktan Kan Basıncı Ölçümü

The relationship between red cell distribution width and resistant hypertension

Aim: Erythrocyte distribution width (RDW) is known to be associated with cardiovascular diseases. Patients with resistant hypertension (RHT) have a higher risk of cardiovascular events. In this study, we aimed to evaluate the relationship between RDW and resistant hy-pertension. Material and Methods: A total of 157 patients, 69 (43%) of them being resistant hyperten-sion, who had 24-hour ambulatory blood pressure measurement (ABPM) were included in this study. RDW and other laboratory parameters were measured after ABPM. Results: The average age in the study population was 57 ± 11, and 77% (121) of the patients were female. Patients were divided into two groups as controlled and RHT. The RDW was significantly higher in the RHT group (14.8±1.4) compared to the CHT group (14.1±1.2); (p=0,02). RDW by multivariable logistic regression analysis (odds ratio [OR]: 1.684, 95% confidence Interval [CI]: 1.250-2.201 p

Keywords:

Red Blood Cell Width, Hypertension, Resistant Hypertension, Controlled Hypertension, Ambulatory Blood Pressure Measurement,

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