Tarik El-Sayed ALI, Salah Abdel-Aziz ABDEL-GHAFFAR, Kamilia Mohamed EL-MAHDY, Somaia Mohamed ABDEL-KARIM

Synthesis, characterization, and antimicrobial activity of some new phosphorus macrocyclic compounds containing pyrazole rings

A simple synthetic method is reported for the preparation of some new phosphorus macrocycles in which the pyrazole rings are appended to a phosphorus atom. The methodology is based on the cyclocondensation reaction of bis(4-formylpyrazolyl) phosphine oxide(1a, 1b) with nitrogen nucleophiles that contain active terminal amino groups. The antimicrobial activities of the synthesized compounds were assayed.

Anahtar Kelimeler:

Key words: Phosphorus macrocycles, pyrazole, cyclocondensation, nitrogen nucleophiles

Synthesis, characterization, and antimicrobial activity of some new phosphorus macrocyclic compounds containing pyrazole rings

Keywords:

pyrazole, cyclocondensation, nitrogen nucleophiles, Phosphorus macrocycles,

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