Secondary Metabolites from Euphorbia helioscopia and Their Vasodepressor Activity

From the aerial parts of Euphorbia helioscopia L. (Euphorbiaceae), a jatrophane diterpene ester, 5,11-jatrophadiene-3-benzoyloxy-7,9,14-tri-acetyloxy-15-ol and 2 lupane derivatives, lup-20(29)-ene-3-acetate and lup-20(29)-ene-3-palmitate, together with common triterpenoids of Euphorbiaceae, 24-methylene cycloartanol, 24-methylenecycloart-3-one, cycloartanol, and stigmast-4-ene-3-one were isolated. The last compounds, lup-20(29)-ene-3-acetate, 24-methylene cycloartanol, 24-methylenecycloart-3-one, cycloartanol, and stigmast-4-ene-3-one, were isolated for the first time from E. helioscopia}. The fractions and the isolates were tested for their vasodepressor effects using Wistar Albino rats, and 5,11-jatrophadiene-3-benzoyloxy-7,9,14-tri-acetyloxy- 15-ol, lup-20(29)-ene-3-acetate, and stigmast-4-ene-3-one were found to possess relevant activity. The structures of all of the compounds were identified with high field spectroscopic methods. The detailed spectroscopic data of compound 1 is given in the present study.

Secondary Metabolites from Euphorbia helioscopia and Their Vasodepressor Activity

From the aerial parts of Euphorbia helioscopia L. (Euphorbiaceae), a jatrophane diterpene ester, 5,11-jatrophadiene-3-benzoyloxy-7,9,14-tri-acetyloxy-15-ol and 2 lupane derivatives, lup-20(29)-ene-3-acetate and lup-20(29)-ene-3-palmitate, together with common triterpenoids of Euphorbiaceae, 24-methylene cycloartanol, 24-methylenecycloart-3-one, cycloartanol, and stigmast-4-ene-3-one were isolated. The last compounds, lup-20(29)-ene-3-acetate, 24-methylene cycloartanol, 24-methylenecycloart-3-one, cycloartanol, and stigmast-4-ene-3-one, were isolated for the first time from E. helioscopia}. The fractions and the isolates were tested for their vasodepressor effects using Wistar Albino rats, and 5,11-jatrophadiene-3-benzoyloxy-7,9,14-tri-acetyloxy- 15-ol, lup-20(29)-ene-3-acetate, and stigmast-4-ene-3-one were found to possess relevant activity. The structures of all of the compounds were identified with high field spectroscopic methods. The detailed spectroscopic data of compound 1 is given in the present study.

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Kaynak Göster

Bibtex @ { tbtkchem142551, journal = {Turkish Journal of Chemistry}, issn = {1300-0527}, eissn = {1303-6130}, address = {}, publisher = {TÜBİTAK}, year = {2006}, volume = {30}, pages = {325 - 332}, doi = {}, title = {Secondary Metabolites from Euphorbia helioscopia and Their Vasodepressor Activity}, key = {cite}, author = {Barla, Aslı and Birman, Hüsniye and Kültür, Şükran and Öksüz, Sevil} }
APA Barla, A , Birman, H , Kültür, Ş , Öksüz, S . (2006). Secondary Metabolites from Euphorbia helioscopia and Their Vasodepressor Activity . Turkish Journal of Chemistry , 30 (3) , 325-332 .
MLA Barla, A , Birman, H , Kültür, Ş , Öksüz, S . "Secondary Metabolites from Euphorbia helioscopia and Their Vasodepressor Activity" . Turkish Journal of Chemistry 30 (2006 ): 325-332 <
Chicago Barla, A , Birman, H , Kültür, Ş , Öksüz, S . "Secondary Metabolites from Euphorbia helioscopia and Their Vasodepressor Activity". Turkish Journal of Chemistry 30 (2006 ): 325-332
RIS TY - JOUR T1 - Secondary Metabolites from Euphorbia helioscopia and Their Vasodepressor Activity AU - Aslı Barla , Hüsniye Birman , Şükran Kültür , Sevil Öksüz Y1 - 2006 PY - 2006 N1 - DO - T2 - Turkish Journal of Chemistry JF - Journal JO - JOR SP - 325 EP - 332 VL - 30 IS - 3 SN - 1300-0527-1303-6130 M3 - UR - Y2 - 2021 ER -
EndNote %0 Turkish Journal of Chemistry Secondary Metabolites from Euphorbia helioscopia and Their Vasodepressor Activity %A Aslı Barla , Hüsniye Birman , Şükran Kültür , Sevil Öksüz %T Secondary Metabolites from Euphorbia helioscopia and Their Vasodepressor Activity %D 2006 %J Turkish Journal of Chemistry %P 1300-0527-1303-6130 %V 30 %N 3 %R %U
ISNAD Barla, Aslı , Birman, Hüsniye , Kültür, Şükran , Öksüz, Sevil . "Secondary Metabolites from Euphorbia helioscopia and Their Vasodepressor Activity". Turkish Journal of Chemistry 30 / 3 (Mart 2006): 325-332 .
AMA Barla A , Birman H , Kültür Ş , Öksüz S . Secondary Metabolites from Euphorbia helioscopia and Their Vasodepressor Activity. Turk J Chem. 2006; 30(3): 325-332.
Vancouver Barla A , Birman H , Kültür Ş , Öksüz S . Secondary Metabolites from Euphorbia helioscopia and Their Vasodepressor Activity. Turkish Journal of Chemistry. 2006; 30(3): 325-332.
IEEE A. Barla , H. Birman , Ş. Kültür ve S. Öksüz , "Secondary Metabolites from Euphorbia helioscopia and Their Vasodepressor Activity", Turkish Journal of Chemistry, c. 30, sayı. 3, ss. 325-332, Mar. 2006
  • ISSN: 1300-0527
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK

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