Secondary metabolites from Phomis syriaca and their antioxidant activities

Secondary metabolites from Phomis syriaca and their antioxidant activities

An iridoid glucoside, lamiide (1); 4 phenylethanoid glycosides, acteoside (2), $beta$-OH acteoside (3), leucosceptoside A (4) and samioside (5); a caffeic acid ester, chlorogenic acid (6); 2 flavone glucosides, luteolin-7-O-glucopyranoside (7) and chrysoeriol-7-O-glucopyranoside (8); and a flavanone aglycone, naringenin (9), were isolated from the aerial parts of Phlomis syriaca. The structures of the isolated compounds were elucidated by means of spectroscopic (UV, IR, 1D- and 2D-NMR, and FAB-MS) methods. Free radical scavenging activity of the isolated compounds was determined using the radical 2,2-diphenyl-1-picrylhydrazyl (DPPH), spectroscopically.

___

  • 1.A. Huber Morath, Phlomis, in "Flora of Turkey and the East Aegean Islands", ed.: P.H.Davis. Vol. 7,pp 102-126, Edinburg University Press, Edinburgh (1982),
  • 2.T. Baytop, "Therapy with Medicinal Plants in Turkey (Past and Present)" 2nd ed. pp. 193, Nobel Tip Kitapevleri, Istanbul (1999).
  • 3.E. Yeşilada, Biodiversity in Turkish Folk Medicine in "Biomolecular Aspects of Biodiversity and Innovative Utilization" Ed. B.Sener, Kluwer Academic, Pleum Publishers, London (2002).
  • 4.İ. Çalış, A.A. Başaran, İ. Saraçoğlu, O. Sticher and P. Rüedi, Phytochemistry 29, 1253-1257 (1990).
  • 5.İ. Saraçoğlu, M. Varel, İ. Çalış and A.A. Dönmez, Turk. J. Chem. 27, 739-747 (2003).
  • 6.T. Ersöz, İ. Saraçoğlu, D. Taşdemir, H. Kırmızıbekmez, A.A. Dönmez, C.M. Ireland and İ. Çalış, Z. Naturforsch., 57c, 221-225 (2002).
  • 7.İ. Saraçoğlu, Ü.Ş. Harput, İ. Çalış and Y. Ogihara, Turk. J. Chem. 26, 133-142 (2002).
  • 8.İ. Çalış, H. Kırmızıbekmez, D. Taşdemir and P. Rüedi, Helv. Chim. Açta. 87, 611-619 (2004).
  • 9.T. Hatano, R. Edamatsu, M. Hiramatsu, A. Mori, Y. Fujita, T. Yasuhara, T. Yoshida and T. Okuda T. Chem. Pharm. Bull. 37, 2016-2021 (1989).
  • 10.A. Bianco, C. Bonini, G. Guiso, C. Iavarone and C. Tragola, Gazz. Chim. Ital. 107, 67-69 (1977).
  • 11.C. Andary, R. Wylde, C. Laffite, G. Privat and F. Winternitz, Phytochemistry, 21, 1123-1127 (1982).
  • 12.S.Kitagawa, H. Tsukamoto, S. Hisade and S. Nishibe, Chem. Pharm. Bull. 32, 1209-1213 (1984).
  • 13.T. Miyase, A. Koizumi, A. Ueno, T. Noro, M. Kuroyanagi, S. Fukushima, Y. Akiyama and T. Takemoto,Chem. Pharm. Bull. 30, 2732-2737 (1982).
  • 14.F.N. Yalçın, T. Ersöz, P. Akbay, İ, Çalış, A.A. Dönmez and O. Sticher, Turk J. Chem. 27, 295-306 (2003).
  • 15.K.R. Markham and V.M. Chari, The Flavonoids: Advances in Research, eds: J.B. Harborne and T.J.Mabry, Chapmari and Hall, London (1982).
  • 16.K.R. Markham and H. Geiger, The Flavonoids: Advances in Research since 1986, ed: J.B. Harborne,Chapman and Hill, London (1994).
  • 17.X.L. Piao, I.H. Park, S.H. Baek, H.Y. Kim, M.K. Park and J.H. Park, J. Ethnopharmacol. 93, 243-246(2004).
  • 18.H. Kırmızıbekmez, S. Piacenta, C. Pizza, A.A. Dönmez, İ. Çalış, Z. Naturforsch. 59b, 609-613 (2004).
  • 19.SBAG2304, Chemotaxonomy of the Genus Phlomis in Turkey (2004).
  • 20.İ. Saraçoğlu, M. Inoue, İ. Çalış and Y. Ogihara, Biol. Pharm. Bull. 18, 1396-1400 (1995).
  • 21.İ. Çalış, H. Kırmızıbekmez, J.A. Beutler, A.A. Dönmez, F.N. Yalçın, E. Kılıç, M. Özalp, P. Rüedi and D.Taşdemir, Turk. J. Chem. 29, 71-81 (2005).
  • 22.P. Montoro, A. Braca, C. Pizza and N. Tommasi, Food Chemistry 92, 349-355 (2005).
Turkish Journal of Chemistry-Cover
  • ISSN: 1300-0527
  • Yayın Aralığı: 6
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

Iridoid, flavonoid, and phenylethanoid glycosides form Wiedemannia orientalis

Cavit KAZAZ, Hilal ÖZBEK, Zühal GÜVENALP, L. Ömür DEMİREZER, Türesin ÜNSALAR

A Novel Approach to the Hydrothermal Synthesis of Anatase Titania Nanoparticles and the Photocatalytic Degradation of Rhodamine B

Murat AKARSU, Meltem ASİLTÜRK, Funda SAYILKAN

Secondary metabolites from Phomis syriaca and their antioxidant activities

İclal SARACOĞLU, Ali Aslan DÖNMEZ, Akito NAGATSU, Ü. Şebnem HARPUT, İhsan ÇALIŞ

Solvent-Free Preparation of Primary Carbamates

Ali Reza MODARRESI-ALAM

Effect of Surfactants on Response of Promethazine PVC-Membranes

Mohsen M. ZAREH, Raga E. Shohiab And Mostafa ABD-EL-FATAH

Secondary Metabolites from Phlomis syriaca and Their Antioxidant Activities

Ü. Şebnem HARPUT, İhsan ÇALIŞ, İclal SARACOĞLU, Ali A. DÖNMEZ, Akito NAGATSU

Investigation of the Cation Complexation by Macrocyclic Ethers using 13C NMR Spin--Lattice Dipolar Relaxation Time Measurements

Çakıl ERK, Matthias HEYDENREICH, And Erich KLEINPETER

Synthesis and Spectroscopic Characterization of Biologically Active Triarylantimony(V) Carboxylates Containing Germanium

Muhammad Kaleem KHOSA, Muhammad MAZHAR, Saqib ALI

Preparation and Characterization of an Aromatic Polyimide and Its Use as a Selective Membrane for H2O2

Ergun EKİNCİ, Süleyman KÖYTEPE, Aziz PAŞAHAN, Turgay SEÇKİN

Iridoid, Flavonoid, and Phenylethanoid Glycosides from Wiedemannia orientalis

Zühal Güvenalp -, Hilal ÖZBEK, Türesin ÜNSALAR, Cavit KAZAZ, L. Ömür DEMİREZER