Preparation and Characterization of an Atenolol Selective Electrode Based on a PVC Matrix Membrane

Atenolol selective electrodes were prepared based on a complex atenolol-phosphotungstate as an active material using the plasticizers di-butyl phosphate (DBP), tri-butyl phosphate (TBP), o-nitro phenyl octyl ether (NPOE) and di-octyl phthalate (DOPH) in a PVC matrix membrane. The properties of the prepared electrodes were studied, namely slope, concentration range, detection limit, lifetime, pH effect and selectivity. The experimental results showed that the best electrode was based on DOPH as plasticizer, displaying a linear range from 1.00 x 10-4 M to 5.00 x 10-2 M with a Nernstian slope of 55.91 mV/decade and correlation coefficient of 0.9995. The detection limit was 5.00 x 10-5 M and the lifetime was around 90 days. The proposed electrode was successfully applied to the determination of atenolol in a pharmaceutical preparation. The average recovery for atenolol determination in tablets was around 98.50%, with standard deviation \pm 0.1.

Preparation and Characterization of an Atenolol Selective Electrode Based on a PVC Matrix Membrane

Atenolol selective electrodes were prepared based on a complex atenolol-phosphotungstate as an active material using the plasticizers di-butyl phosphate (DBP), tri-butyl phosphate (TBP), o-nitro phenyl octyl ether (NPOE) and di-octyl phthalate (DOPH) in a PVC matrix membrane. The properties of the prepared electrodes were studied, namely slope, concentration range, detection limit, lifetime, pH effect and selectivity. The experimental results showed that the best electrode was based on DOPH as plasticizer, displaying a linear range from 1.00 x 10-4 M to 5.00 x 10-2 M with a Nernstian slope of 55.91 mV/decade and correlation coefficient of 0.9995. The detection limit was 5.00 x 10-5 M and the lifetime was around 90 days. The proposed electrode was successfully applied to the determination of atenolol in a pharmaceutical preparation. The average recovery for atenolol determination in tablets was around 98.50%, with standard deviation \pm 0.1.

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Kaynak Göster

Bibtex @ { tbtkchem142504, journal = {Turkish Journal of Chemistry}, issn = {1300-0527}, eissn = {1303-6130}, address = {}, publisher = {TÜBİTAK}, year = {2007}, volume = {31}, pages = {75 - 82}, doi = {}, title = {Preparation and Characterization of an Atenolol Selective Electrode Based on a PVC Matrix Membrane}, key = {cite}, author = {Nassory, Nabil S. and Alı, Shahbaz A. Maki And Mutaz A. and Alı, Mutaz A.} }
APA Nassory, N , Alı, S , Alı, M . (2007). Preparation and Characterization of an Atenolol Selective Electrode Based on a PVC Matrix Membrane . Turkish Journal of Chemistry , 31 (1) , 75-82 .
MLA Nassory, N , Alı, S , Alı, M . "Preparation and Characterization of an Atenolol Selective Electrode Based on a PVC Matrix Membrane" . Turkish Journal of Chemistry 31 (2007 ): 75-82 <
Chicago Nassory, N , Alı, S , Alı, M . "Preparation and Characterization of an Atenolol Selective Electrode Based on a PVC Matrix Membrane". Turkish Journal of Chemistry 31 (2007 ): 75-82
RIS TY - JOUR T1 - Preparation and Characterization of an Atenolol Selective Electrode Based on a PVC Matrix Membrane AU - Nabil S. Nassory , Shahbaz A. Maki And Mutaz A. Alı , Mutaz A. Alı Y1 - 2007 PY - 2007 N1 - DO - T2 - Turkish Journal of Chemistry JF - Journal JO - JOR SP - 75 EP - 82 VL - 31 IS - 1 SN - 1300-0527-1303-6130 M3 - UR - Y2 - 2021 ER -
EndNote %0 Turkish Journal of Chemistry Preparation and Characterization of an Atenolol Selective Electrode Based on a PVC Matrix Membrane %A Nabil S. Nassory , Shahbaz A. Maki And Mutaz A. Alı , Mutaz A. Alı %T Preparation and Characterization of an Atenolol Selective Electrode Based on a PVC Matrix Membrane %D 2007 %J Turkish Journal of Chemistry %P 1300-0527-1303-6130 %V 31 %N 1 %R %U
ISNAD Nassory, Nabil S. , Alı, Shahbaz A. Maki And Mutaz A. , Alı, Mutaz A. . "Preparation and Characterization of an Atenolol Selective Electrode Based on a PVC Matrix Membrane". Turkish Journal of Chemistry 31 / 1 (Ocak 2007): 75-82 .
AMA Nassory N , Alı S , Alı M . Preparation and Characterization of an Atenolol Selective Electrode Based on a PVC Matrix Membrane. Turk J Chem. 2007; 31(1): 75-82.
Vancouver Nassory N , Alı S , Alı M . Preparation and Characterization of an Atenolol Selective Electrode Based on a PVC Matrix Membrane. Turkish Journal of Chemistry. 2007; 31(1): 75-82.
IEEE N. Nassory , S. Alı ve M. Alı , "Preparation and Characterization of an Atenolol Selective Electrode Based on a PVC Matrix Membrane", Turkish Journal of Chemistry, c. 31, sayı. 1, ss. 75-82, Oca. 2007
  • ISSN: 1300-0527
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK

11.7b 6.7b

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