Multiple objective optimization of air assisted liquid-liquid microextraction combined with solidified floating organic drop microextraction for simultaneous determination of trace copper and nickel

The impact of rising levels of various heavy metals in the environment from multiple industrial, agriculture, domestic, and technological activities is of great concerns, as heavy metals cause serious health effects for both humans and wildlife. An effective and green chemistry procedure was used for simultaneous extraction of ultra-trace copper and nickel ions in natural waters (e.g. river and well waters) by air assisted liquid-liquid microextraction combined with solidified floating organic drop microextraction (AALLMESFOD). The extraction of metal ions was conducted in a timescale of several minutes by conversion to metal chelates using sodium diethyldithiocarbamate (DDTC) as a chelating agent prior to AALLME-SFOD procedure, and 1-dodecanol as an extraction solvent to initiate the phase separation of the complex. The response surface methodology (RSM) and central composite design (CCD) were used to optimize the large number of experimental variables (i.e. pH, solvent volume, ligand volume, % NaCl). The analysis of variance (ANOVA) has been applied to evaluate all parameters and their mutual interactions on the extraction yields. The desirability function of Derringer and Suich was applied as a metric for optimization of multiple response variables. The optimized AALLME-SFOD technique proved to be highly effective for the pre-concentration of Cu(II) and Ni(II) from a range of aqueous media (i.e. river and well waters) and provides a quick and easy method, while utilizing compact and low cost equipment with micro-volume organic solvent consumption (e.g. ~120 μL for 5 mL water samples). Quantitation of copper and nickel with Graphite furnace atomic absorption spectroscopy (GFAAS) under the optimum conditions, were linear over the range of (20–100) and (20–200) ng $L^{–1}$ respectively. Limit of detection for Ni(II) was at 4.5 ng $L^{–1} and 10.4 ng L^{–1}$ for Cu(II).

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1. El-Shahawi M, Al-Saidi H. Dispersive liquid-liquid microextraction for chemical speciation and determination of ultra-trace concentrations of metal ions. TrAC Trends in Analytical Chemistry 2013; 44: 12-24.
2. Fu F, Wang Q. Removal of heavy metal ions from wastewaters: a review. Journal of Environmental Management 2011; 92 (3): 407-418.
3. Haarstad K, Bavor H, Mæhlum T. Organic and metallic pollutants in water treatment and natural wetlands: a review. Water Science and Technology 2012; 65 (1): 76-99.
4. Nagajyoti PC, Lee KD, Sreekanth T. Heavy metals, occurrence and toxicity for plants: a review. Environmental Chemistry Letters 2010; 8 (3): 199-216.
5. Yamashita Y, Jaffé R. Characterizing the interactions between trace metals and dissolved organic matter using excitation−emission matrix and parallel factor analysis. Environmental Science & Technology 2008; 42 (19): 7374-7379.
6. Yogarajah N, Tsai SS. Detection of trace arsenic in drinking water: challenges and opportunities for microfluidics. Environmental Science: Water Research & Technology 2015; 1 (4): 426-447.
7. Camcı Y, Bişgin AT, Sürme Y, Uçan M, Narin İ. Micelle mediated extraction and flame atomic absorption spectrometric determination of trace amounts of copper in different mushroom species. Journal of Analytical Chemistry 2020; 75 (9): 1131-1136.
8. Bişgin AT, Sürme Y, Uçan M, Narin I. Simultaneous preconcentration and determination of Cu2+, Ni2+ and Cd2+ by micelle mediated extraction in food and water samples. Journal of the Chilean Chemical Society 2016; 61 (2): 2990-2995.
9. Aguirre MÁ, Baile P, Vidal L, Canals A. Metal applications of liquid-phase microextraction. TrAC Trends in Analytical Chemistry 2019: 112; 241-247.
10. Ma J, Lu W, Chen L. Recent advances in dispersive liquid-liquid microextraction for organic compounds analysis in environmental water: a review. Current Analytical Chemistry 2012; 8 (1): 78-90.
11. Mansour FR, Danielson ND. Solidification of floating organic droplet in dispersive liquid-liquid microextraction as a green analytical tool. Talant 2017; 170: 22-35.
12. Souza-Silva ÉA, Jiang R, Rodríguez-Lafuente A, Gionfriddo E, Pawliszyn J. A critical review of the state of the art of solid-phase microextraction of complex matrices I. Environmental analysis. TrAC Trends in Analytical Chemistry 2015; 71: 224-235.
13. Jagirani MS, Soylak M. A review: recent advances in solid phase microextraction of toxic pollutants using nanotechnology scenario. Microchemical Journal 2020; 159: 105436.
14. Liu H, Dasgupta PK. Analytical chemistry in a drop. Solvent extraction in a microdrop. Analytical Chemistry 1996; 68 (11): 1817-1821.
15. Rezaee M, Yamini Y, Faraji M. Evolution of dispersive liquid–liquid microextraction method. Journal of Chromatography A 2010; 1217 (16): 2342-2357.
16. Soylak M, Ozdemir B, Yilmaz E. An environmentally friendly and novel amine-based liquid phase microextraction of quercetin in food samples prior to its determination by UV–vis spectrophotometry. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2020; 243: 118806.
17. Rezaee M, Assadi Y, Milani Hosseini M-R, Aghaee E, Ahmadi F et al. Determination of organic compounds in water using dispersive liquid–liquid microextraction. Journal of Chromatography A 2006; 1116 (1): 1-9.
18. Saraji M, Boroujeni MK. Recent developments in dispersive liquid–liquid microextraction. Analytical and Bioanalytical Chemistry 2014; 406 (8): 2027-2066.
19. Xiong C, Ruan J, Cai Y, Tang Y. Extraction and determination of some psychotropic drugs in urine samples using dispersive liquid–liquid microextraction followed by high-performance liquid chromatography. Journal of Pharmaceutical and Biomedical Analysis 2009; 49 (2): 572-578.
20. Zanjani MRK, Yamini Y, Shariati S, Jönsson JÅ. A new liquid-phase microextraction method based on solidification of floating organic drop. Analytica Chimica Acta 2007; 585 (2): 286-293.
21. Kamarei F, Ebrahimzadeh H, Asgharinezhad AA. Optimization of simultaneous derivatization and extraction of aliphatic amines in water samples with dispersive liquid–liquid microextraction followed by HPLC. Journal of Separation Science 2011; 34 (19): 2719-2725.
22. Lili L, Xu H, Song D, Cui Y, Hu S et al. Analysis of volatile aldehyde biomarkers in human blood by derivatization and dispersive liquid– liquid microextraction based on solidification of floating organic droplet method by high performance liquid chromatography. Journal of Chromatography A 2010; 1217 (16): 2365-2370.
23. Fathirad F, Afzali D, Mostafavi A, Ghanbarian M. Ultrasound-assisted emulsification solidified floating organic drops microextraction of ultra trace amount of Te (IV) prior to graphite furnace atomic absorption spectrometry determination. Talanta 2012; 88: 759-764.
24. Sajedi-Amin S, Asadpour-Zeynali K, Khoubnasabjafari M, Rashidi F, Jouyban A. Development and validation of ultrasound assisted and dispersive liquid-liquid microextractions combined with HPLC-UV method for determination of bosentan in human plasma and urine. Journal of the Brazilian Chemical Society 2017; 28 (5): 868-877.
25. Spietelun A, Marcinkowski Ł, De la Guardia M, Namieśnik J. Green aspects, developments and perspectives of liquid phase microextraction techniques.Talanta 2014; 119: 34-45.
26. Farahmand F, Ghasemzadeh B, Naseri A. Air-assisted liquid–liquid microextraction using floating organic droplet solidification for simultaneous extraction and spectrophotometric determination of some drugs in biological samples through chemometrics methods. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2018; 188: 72-79.
27. Sricharoen P, Limchoowong N, Techawongstien S, Chanthai S. A novel extraction method for β-carotene and other carotenoids in fruit juices using air-assisted, low-density solvent-based liquid–liquid microextraction and solidified floating organic droplets. Food Chemistry 2016; 203: 386-393.
28. You X, Xing Z, Liu F, Zhang X. Air-assisted liquid–liquid microextraction by solidifying the floating organic droplets for the rapid determination of seven fungicide residues in juice samples. Analytica Chimica Acta 2015; 875: 54-60.
29. Jahromi EZ, Bidari A, Assadi Y, Hosseini MRM, Jamali MR. Dispersive liquid–liquid microextraction combined with graphite furnace atomic absorption spectrometry: Ultra trace determination of cadmium in water samples. Analytica Chimica Acta 2007; 585 (2): 305-311.
30. Mirzaei M, Behzadi M, Abadi NM, Beizaei A. Simultaneous separation/preconcentration of ultra trace heavy metals in industrial wastewaters by dispersive liquid–liquid microextraction based on solidification of floating organic drop prior to determination by graphite furnace atomic absorption spectrometry. Journal of Hazardous Materials 2011; 186 (2-3): 1739-1743.
31. Naseri MT, Hemmatkhah P, Hosseini MRM, Assadi Y. Combination of dispersive liquid–liquid microextraction with flame atomic absorption spectrometry using microsample introduction for determination of lead in water samples. Analytica Chimica Acta 2008; 610 (1): 135-141.
32. Bişgin AT. Surfactant-assisted emulsification and surfactant-based dispersive liquid–liquid microextraction method for determination of Cu (II) in food and water samples by flame atomic absorption spectrometry. Journal of AOAC International 2019; 102 (5): 1516-1522.
33. Sürme Y, Bişgin A, Uçan M, Narin İ. Cloud point extraction and flame atomic absorption spectrometric determination of Cd (II) in industrial and environmental samples. Journal of Analytical Chemistry 2018; 73 (2): 140-144.
34. Moens L, De Smaele T, Dams R, Van Den Broeck P, Sandra P. Sensitive, simultaneous determination of organomercury, -lead, and-tin compounds with headspace solid phase microextraction capillary gas chromatography combined with inductively coupled plasma mass spectrometry. Analytical Chemistry 1997; 69 (8): 1604-1611.
35. Derringer G, Suich R. Simultaneous optimization of several response variables. Journal of Quality Technology 1980; 12 (4): 214-219.
36. Ebrahimi P, Hadjmohammadi MR. Optimization of the separation of coumarins in mixed micellar liquid chromatography using Derringer’s desirability function. Journal of Chemometrics 2007; 21 (1-2): 35-42.
37. Zolgharnein J, Shahmoradi A, Ghasemi JB. Comparative study of Box–Behnken, central composite, and Doehlert matrix for multivariate optimization of Pb (II) adsorption onto Robinia tree leaves. Journal of Chemometrics 2013; 27 (1-2): 12-20.
38. Elik A, Unal Y, Altunay N. Development of a chemometric-assisted deep eutectic solvent-based microextraction procedure for extraction of caffeine in foods and beverages. Food Additives & Contaminants: Part A 2019; 36 (8): 1139-1150.
39. Atanassova D, Stefanova V, Russeva E. Co-precipitative pre-concentration with sodium diethyldithiocarbamate and ICP-AES determination of Se, Cu, Pb, Zn, Fe, Co, Ni, Mn, Cr and Cd in water.Talanta 1998; 47 (5): 1237-1243.
40. Cui C, He M, Hu B. Membrane solid phase microextraction with alumina hollow fiber on line coupled with ICP-OES for the determination of trace copper, manganese and nickel in environmental water samples. Journal of Hazardous Materials 2011; 187 (1-3): 379-385.
41. Dadfarnia S, Shakerian F, Shabani AMH. Suspended nanoparticles in surfactant media as a microextraction technique for simultaneous separation and preconcentration of cobalt, nickel and copper ions for electrothermal atomic absorption spectrometry determination. Talanta 2013; 106: 150-154.
42. Faraji M, Yamini Y, Saleh A, Rezaee M, Ghambarian M et.al. A nanoparticle-based solid-phase extraction procedure followed by flow injection inductively coupled plasma-optical emission spectrometry to determine some heavy metal ions in water samples. Analytica Chimica Acta 2010; 659 (1-2): 172-177.
43. Jiang H, Qin Y, Hu B. Dispersive liquid phase microextraction (DLPME) combined with graphite furnace atomic absorption spectrometry (GFAAS) for determination of trace Co and Ni in environmental water and rice samples. Talanta 2008; 74 (5): 1160-1165.
44. Liang P, Yu J, Yang E, Mo Y. Determination of cobalt in food and water samples by ultrasound-assisted surfactant-enhanced emulsification microextraction and graphite furnace atomic absorption spectrometry. Food Analytical Methods 2014; 7 (7): 1506-1512.
45. Sorouraddin S M, Farajzadeh M A, Ghorbani M. In situ-produced $CO_2$ -assisted dispersive liquid–liquid microextraction for extraction and preconcentration of cobalt, nickel, and copper ions from aqueous samples followed by graphite furnace atomic absorption spectrometry determination. Journal of the Iranian Chemical Society 2018; 15 (1): 201-209.