Physiological conditions in the growth habitat of yeast cells dramatically changes the gene expression pattern. In this study, it was shown that transcription of the SUC2gene, which encodes the cytoplasmic and secreted enzyme invertase, is modulated according to the environmental conditions in the yeast Saccharomyces cerevisiae. Hyperosmotic stress and oxidative stress repressed the transcription of the SUC2gene up to 50%. However, preconditioning of the yeast cells prevented the negative effects of osmotic stress on SUC2gene transcription. These results clearly show that, apart from the control of invertase activity and its secretion, osmotic stress and oxidative stress also represses transcription of the SUC2gene in the yeast S. cerevisiae.

Physiological conditions in the growth habitat of yeast cells dramatically changes the gene expression pattern. In this study, it was shown that transcription of the SUC2gene, which encodes the cytoplasmic and secreted enzyme invertase, is modulated according to the environmental conditions in the yeast Saccharomyces cerevisiae. Hyperosmotic stress and oxidative stress repressed the transcription of the SUC2gene up to 50%. However, preconditioning of the yeast cells prevented the negative effects of osmotic stress on SUC2gene transcription. These results clearly show that, apart from the control of invertase activity and its secretion, osmotic stress and oxidative stress also represses transcription of the SUC2gene in the yeast S. cerevisiae.