Akshay TİWARİ

383101

Mimic toxicity of Beta-blocker drugs by structural base descriptors

Mimic toxicity of Beta-blocker drugs by structural base descriptors

QSAR study has been carried out on the set of 35 Beta-blocker drugs for the modelling of toxicity (Ld50), using topological indices. The stepwise multilinear regression analysis method is used for modelling and the obtained models are critically discussed and examined by various types of cross validation parameters
Keywords:

Beta-Blockers, LD50, topological index, regression analysis, Beta-Blockers , LD50, topological index regression analysis,

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  • Agrawal, V. K.; Srivastava, R; Khadkar, P. V. Bioorg. Med. Chem., 2001, 9, 3287
  • Agrawal, V. K.; Singh, J., P. V. Bioorg. Med. Chem., 2002, 10, 3981
Turkish Computational and Theoretical Chemistry-Cover
  • ISSN: 2587-1722
  • Başlangıç: 2017
  • Yayıncı: Koray SAYIN
Arşiv
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