Yüksek doz kafur alımına bağlı nöbet
Kafur hidroaromatik terpene grubunun bir siklik ketonudur. Topikal öksürük kesici, ağrı kesici, anestezik ve kaşıntı önleyicisi olarak kafur reçeteli ya da reçetesiz olarak sıkça kullanılmaktadır. Ebeveynler ve hekimler tarafından masum olduğu düşünülen kafur düşük dozlarda bile çocuklarda ciddi zehirlenmeye neden olabilen, her evde bulunan bir maddedir. Ağızdan kafur alımı sonrası yaygın tonik klonik nöbet geçirme yakınması ile hastaneye başvuran iki yaşında kız olgu sunulmuştur
Seizures due to high dose camphor ingestion
Camphor is a cyclic ketone of the hydro aromatic terpene group. Today it is frequently used as a prescription or non-prescription topical antitussive, analgesic, anesthetic and antipruritic agent. Camphor which is considered an innocent drug by parents and physicians is a common household item which can lead to severe poisoning in children even when taken in small amounts. Neurotoxicity in the form of seizures can ocur soon after ingestion. A two-year old female patient who presented with a complaint of generalized tonic-clonic seizures after oral ingestion of camphor is presented
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- Gennaro AR. Anti-infectives. In: David T, Paul B, (eds). Remington: The science and practice of pharmacy. 21st edt. Philadelphia: Lippincott Williams & Wilkins; 2005. p. 1284.
- Love JN, Sammon M, Smereck J. Are one or two dange- rous? Camphor exposure in toddlers. J Emerg Med 2004; 27: 49-54. [CrossRef ]
- Eldridge DL, Van Eyk J, Kornegay C. Pediatric toxicology. Emerg Med Clin North Am 2007; 25: 283-308. [CrossRef ]
- Manoguerra AS, Erdman AR, Wax PM, et al. Camphor poisoning: an evidence-based practice guideline for out- of-hospital management. Clin Toxicol (Phila) 2006; 44: 357-70. [CrossRef ]
- Camphor revisited: focus on toxicity. Committee on Drugs. American Academy of Pediatrics. Pediatrics 1994; 94: 127-8.
- Michael JB, Sztajnkrycer MD. Deadly pediatric poisons: nine common agents that kill at low doses. Emerg Med Clin North Am 2004; 22: 1019-50. [CrossRef ]
- Gouin S, Patel H. Unusual cause of seizure. Pediatr Emerg Care 1996; 12: 298-300. [CrossRef ]
- Lahoud CA, March JA, Proctor DD. Campho-Phenique ingestion: an intentional overdose. South Med J 1997; 90: 647-8. [CrossRef ]
- Dean BS, Burdick JD, Geotz CM, Bricker JD, Krenzelok EP. In vivo evaluation of the adsorptive capacity of acti- vated charcoal for camphor. Vet Hum Toxicol 1992; 34: 297-300.
- Ruha AM, Graeme KA, Field A. Late seizure following ingestion of Vicks VapoRub. Acad Emerg Med 2003; 10: 691. [CrossRef ]