Kırım Kongo kanamalı ateşi Çağrılı Editör

Kırım Kongo kanamalı ateşi KKKA virüsü insanlarda 30 ölüm oranına ulaşan şiddetli kanamayla seyreden hastalığa neden olmaktadır Tıbbi olarak önemli kene kaynaklı hastalıklardan en geniş coğrafik dağılıma sahip olanıdır Hayvanlarda daha sık görülmekle beraber hastalık etkeni olduğu bugüne kadar gösterilememiştir ancak insanlarda tek tük olgular ya da salgınlar şeklinde ağır kanama ile seyreden klinik tablolara neden olabilir Hastalığın akut bulguları yaygın ağrı miyalji ateş bulantı kusma karın ağrısı ishal ekimoz ve kanama ile yüksek transaminaz değerleri trombositopeni ve lökopeni ile belirgin labaratuvar bulguları şeklindedir Erken konulan tanı ve başlanılan tedavi ölüm oranını azalttığı ve enfeksiyonun ikincil olarak yayılımını önlediği için kanamalı hastalığın ilk ortaya çıkan özelliklerinin bilinmesi önemlidir Tedavinin esasını destek tedavisi oluşturmakla birlikte ribavirinin KKKA hastalarda antiviral amaçlı kullanımı söz konusudur Türk Ped Arş 2008; 43: 108 18 Anahtar kelimeler: Kene Kırım Kongo kanamalı ateşi viral kanamalı ateş

Anahtar Kelimeler:

Kene, Kırım Kongo kanamalı ateşi, viral kanamalı ateş

Crimean Congo haemorrhagic fever Invited Editor

Crimean Congo haemorrhagic fever CCHF virüs causes severe disease in humans with a mortality reaching 30 It has the most extensive geographic distribution among the medically important tick borne viral diseases Although it is more frequently recovered from animals without any symptoms sporadic cases or epidemics may also be seen in human beings Acute course of the disease appears with symptoms of generalized pain myalgia fever nausea vomiting abdominal pain diarrhoea ecchymoses and bleeding and findings of elevated liver enzymes thrombocytopenia and leukopenia The knowledge of the presenting features of haemorrhagic fevers is necessary for the clinician as early diagnosis and treatment might potentially decrease mortality and the chance of secondary spread of the infection Ribavirin has been tried in the treatment of Crimean Congo haemorrhagic fever Turk Arch Ped 2008; 43: 108 18 Key words: Crimean Congo haemorrhagic disease tick borne viral haemorrhagic disease

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