Hatay'da iyot eksikliği olan kırsal bölge ile iyot eksikliği olmayan kent merkezinde 6-12 yaş çocuklarda idrarda iyot, bakır, çinko, selenyum ve molibden düzeyleri

Amaç: İyot eksikliğine bağlı tiroid hastalıkları ülkemizde ve Dünyada yaygın olarak görülmektedir. Bu çalışmada ülkemizin Hatay ilinde iki okulda (endemik guatr bölgesinde) 6-12 yaş arası çocuklarda idrarda iyot eksikliği ve ona eşlik edebilecek selenyum, çinko, bakır ya da molibden eksikliğinin olup olmadığını araştır- mayı amaçladık. Gereç ve Yöntemler: Bu çalışma sahada yapılan olgu kontrol ça- lışması olup, çalışmaya 6-12 yaş arası öğrenciler dahil edilmiştir. İlimiz merkezine bağlı Tanışma köyünden 114 olgu Hatay şehir merkezinden (Antakya) 100 olgu çalışmaya alındı. Çalışmaya alı- nan öğrencilerin idrar örneklerinden iyot, selenyum, çinko, bakır ve molibden seviyeleri ölçüldü. Bulgular: İyot eksikliği Tanışma Köyünde sırasıyla ciddi (%5), orta (%18,4) ve hafif (%43) olarak belirlendi. Hatay merkezde %7 hafif iyot eksikliği saptandı. Kontrol grubunda orta ve ağır iyot eksik- liğine rastlanmadı. Gruplar arasında idrar iyot atılımında anlamlı fark saptandı (p

Iodine, copper, zinc, selenium and molybdenum levels in children aged between 6 and 12 years in the rural area with iodine deficiency and in the city center without iodine deficiency in Hatay

Aim: Thyroid diseases related with iodine deficiency are observed commonly in our country and in the world. In this study, we aimed to investigate iodine deficiency in urine and selenium, zinc, copper or molybdenum deficiencies which may accompany this in children aged between 6 and 12 years in two schools in the province of Hatay (endemic goitre region). Material and Methods: This study is a case-control field-study in which students aged between 6 and 12 years were included. One hundred fourteen subjects from the village of Tanışma related to the center of our province and 100 subjects from the city center of Hatay (Antakya) were included in the study. Iodine, selenium, zinc, copper and molybdenum levels were measured in the urine samples of the students included in the study. Results: Iodine deficiency was found with a severe (5%), moder- ate (18.4%) and mild degree (43%), respectively in the village of Tanışma. Mild iodine deficiency (7%) was found in the center of Hatay. No moderate and severe iodine deficiency was found in the control group. A significant difference was found between the groups in terms of urine iodine excretion (p

___

  • Nyenwe EA, Dagogo-Jack S. Iodine deficiency disorders in the iodine-replete environment. Am J Med Sci 2009; 337: 37-40. [CrossRef]
  • Zimmermann MB, Jooste PL, Pandav CS. The iodine deficiency disorders. Lancet 2008; 372: 1251-62. [CrossRef]
  • Assey VD, Peterson S, Kimboka S, et al. Tanzania national survey on iodine deficiency: impact after twelve years of salt iodation. BMC Public Health 2009; 9: 319. [CrossRef]
  • Zimmermann MB. Iodine deficiency. Endocr Rev 2009; 30: 376- 408. [CrossRef]
  • Crill CM, Iodine in enteral and parenteral nutrition. Best Pract Res Clin Endocrinal Metab 2010; 24: 143-58. [CrossRef]
  • Zimmermann MB. Iodine deficiency in pregnancy and the ef- fects of maternal iodine supplementation on the offspring: a review. Am J Clin Nutr 2009; 89: 668-72. [CrossRef]
  • World Health Organization, United Nations Children’s Fund, International Council for the Control of Iodine Deficiency Di- sorders. Assessment of Iodine deficiency disorders and monito- ring their elimination. 3rd edition. Geneva: WHO, 2007.
  • Andersson M, de Benoist B, Rogers L. Epidemiology of iodine deficiency: Salt iodisation and iodine status. Best Pract Res Clin Endocrinol Metab 2010; 24: 1-11. [CrossRef]
  • Abuye C, Berhane Y. The goitre rate, its association with repro- ductive failure, and the knowledge of iodine deficiency disor- ders (IDD) among women in Ethiopia: Cross-section commu- nity based study. BMC Public Health 2007; 7: 316. [CrossRef]
  • Andersson M, Takkouche B, Egli I, Allen HE, de Benoist B. Cur- rent global iodine status and progress over the last decade to- wards the elimination of iodine deficiency. Bull World Health Organ 2005; 83: 518-25.
  • Tamam M, Adalet I, Bakir B, et al. Diagnostic spectrum of con- genital hypothyroidism in Turkish children. Pediatr Int 2009; 51: 464-8. [CrossRef]
  • Cranston MM, Ryan MA, Smith TC, Sevick CJ, Brodine SK. Hypoth- yroidism among military infants born in countries of varied iodine nutrition status. BMC Endocr Disord 2010; 10: 2. [CrossRef]
  • Agarval J, Pandav CS, Karmarkar MG, Nair S. Community moni- toring of the national iodine deficiency disorders control prog- ramme in the national capital region of Delhi. Publ Heath Nutr 2010; 1: 1-4.
  • Zimmermann MB, Crill CM. Iodine in enteral and parenteral nutrition. Best Pract Res Clin Endokrinol Metab 2010; 24: 143-58. [CrossRef]
  • Untoro J, Timmer A, Schulting W. The challenges of iodine supplementation: a public health programme perspective. Best Pract Res Clin Endocrinol Metab 2010; 24: 89-99. [CrossRef]
  • Melse Bonstra A, Jaiswal N. Iodine deficiency in pregnancy, in- fancy and childhood and its consequences for brain develop- ment. Best Pract Res Clin Endocrinol Metab 2010; 24: 29-38. [CrossRef]
  • Bayram F, Beyazyıldız A, Gökçe C, et al. The prevalence of io- dine deficiency, serum thyroglobulin, anti-thyroglobulin and thyroid peroxidase antibody levels in the urban areas of Kay- seri, Central Anatolia. Exp Clin Endocrinol Diabetes 2009; 117: 64-8. [CrossRef]
  • Aydin K, Kendirci M, Kurtoğlu S, Karaküçük EI, Kiriş A. Iodi- ne and selenium deficiency in school-children in an endemic goiter area in Turkey. J Pediatr Endocrinol Metab 2002; 15: 1027-31. [CrossRef]
  • Behrman RE, Kliegman RM, Jenson HB. Acrodermatitis Enthe- ropathica. Nelson’s textbook of paediatrics. 17th edition. USA, Saunders Elsevier 2004; 661: 2248-9.
  • WHO, UNICEF and ICCIDD. Assessment of iodine defici- ency disorders and monitoring their elimination. A guide for programme managers. WHO/NHD/01.1. 2nd edition. Geneva: WHO, 2001.
  • Alan HB, Tietz Wu. Clinical Guide to laboratory Tests; section II, general clinical tests. 4th edition, California: WB Saunders Company 2006; 2: 32-1202.
  • Medani AM, Elnour AA, Saeed AM. Endemic goiter in the Sudan despite long-standing programmers for the control of iodine deficiency disorders. Bull World Health Organ 2011; 89: 121-6. [CrossRef]
  • Carvalho AL, de Souza Meirelles CJ, Oliveira LA, Costa TM, Na- varro AM. Excessive iodine intake in schoolchildren. Eur J Nutr 2012; 51: 557-62. [CrossRef]
  • Gallego ML, Loango N, Londoño AL, Landazuri P. Urinary iodi- ne excretion levels in schoolchildren from Quindío, 2006-2007Rev Salud Publica (Bogota) 2009; 11: 952-60. [CrossRef]
  • Pandav CS, Krishnamurthy P, Sankar R, Yadav K, Palanivel CKarmarkar MG. A review of tracking progress towards elimina- tion of Iodine deficiency disorders in Tamil Nadu, India. Indian J Public Health 2010; 54: 120-5. [CrossRef]
  • Kandhro GA, Kazi TG, Sirajuddin, et al. Effects of selenium supplementation on iodine and thyroid hormone status in a selected population with goitre in Pakistan. Clin Lab 2011; 57575-85.
  • Thomson CD, Campbell JM, Miller J, Skeaff SA, Livingstone VSelenium and iodine supplementation: effect on thyroid functi- on of older New Zealanders. Am J Clin Nutr 2009; 90: 1038-46[CrossRef]
  • Keshteli AH, Hashemipour M, Siavash M, Amini M. Selenium deficiency as a possible contributor of goiter in schoolchildren of Isfahan, Iran. Biol Trace Elem Res 2009; 129: 70-7. [CrossRef]
  • Kandhro GA, Kazi TG, Afridi HI, et al. Effect of zinc supplemen- tation on the zinc level in serum and urine and their relation to thyroid hormone profile in male and female goitrous patients. Clin Nutr 2009; 28: 162-8. [CrossRef]
  • Moaddab MH, Keshteli AH, Dastjerdi MS, et al. Zinc status in goitrous school children of Semirom, Iran. J Res Med Sci 2009; 14: 165-70.
  • Keshteli AH, Hashemipour M, Siavash M, Kelishadi R, Amini M. High prevalence of goiter in schoolchildren in Isfahan; zinc deficiency does not play a role. Endokrynol Pol 2010; 61: 287-90.
  • Kazi TG, Kandhro GA, Afridi HI, et al. Interaction of copper with iron, iodine, and thyroid hormone status in goitrous patients. Biol Trace Elem Res 2010; 134: 265-79. [CrossRef]
  • Rasmussen LB, Schomburg L, Köhrle J, et al. Selenium status, thyroid volume and multiple nodule formation in an area with mild iodine deficiency. Eur J Endocrinol 2010; 164: 585-90. [CrossRef]
  • Carvalho AL, Meirelles CJ, Oliveira LA, Costa TM, Navarro AM. Ex- cessive iodine intake in schoolchildren. Eur J Nutr 2012; 51: 557-62. [CrossRef]
  • Giray B, Arnaud J, Sayek I, Favier A, Hincal F. Trace elements status in multinodular goiter. J Trace Elem Med Biol 2010; 24: 106-10. [CrossRef]
Türk Pediatri Arşivi-Cover
  • ISSN: 1306-0015
  • Başlangıç: 2015
  • Yayıncı: Alpay Azap
Sayıdaki Diğer Makaleler

SOX9 geninde yeni bir mutasyon saptanan kampomelik displazi olgusu

Esin YALINBAŞ, Kadri KARAER, Zafer YÜKSEL, Gerd SCHERER

Anhidrotik doğumsal ağrıya duyarsızlık sendromlu bir olgu

Derya CEVİZLİ, Elif ARIK, Ahmet Kağan ÖZKAYA, Ekrem GÜLER, Ali Rıza NAMLI, Olcay GÜNGÖR

Hatay'da iyot eksikliği olan kırsal bölge ile iyot eksikliği olmayan kent merkezinde 6-12 yaş çocuklarda idrarda iyot, bakır, çinko, selenyum ve molibden düzeyleri

Özlem SANGÜN, Nazan SAVAŞ, Mustafa DİDİN, Zeki AYDIN, Murat ÖKTEM, Seher MISIROĞLU, Tanju ÇELİK, Hasan ÖZTÜRK, Selim KURTOĞLU

Kronik hastalığı olmayan çocuklarda tamamlayıcı ve alternatif tıp kullanımı

Tuba TUNCEL, Velat ŞEN, Selvi KELEKÇİ, Müsemma KARABEL, Duran KARABEL, Cahit ŞAHİN, Ünal ULUCA, Yusuf Kenan HASPOLAT

Sağlıklı çocuk izlem polikliniğinde çocukların büyüme durumu ve etkili etmenler

Hüseyin CAN, Ufuk BEYAZOVA, Sercan Bulut ÇELİK, Figen ŞAHİN

Bacaklarda ağrılı şişlik ve döküntüler olan sekiz yaşında erkek hasta

Bahar BÜYÜKKARAGÖZ, Aysun YILMAZ ÇALTIK, Zennure TAKCI, Servet GÜREŞCİ, Mesut KOÇAK, Emine Hafize ERDENİZ, Uğur Ufık IŞIN, Sacit GÜNBEY

Boy kısalığı ile başvuran erkek çocukta tanısal bir ipucu: Testiküler hacim artışı

Nurcan CEBECİ

Çocuklarda idrar yolu enfeksiyonu etkenleri ve antibiyotik dirençlerinin beş yıllık değerlendirmesi

Haluk ERDOĞAN, Halit KAPLAN, Bayram ÇOBAN, Burhan TOPAL, Nesrin ÜLKÜ, Esra BAKIN

Çocuklarda hematopoetik kök hücrenakli

Mehmet Akif YEŞİLİPEK

Yenidoğan yoğun bakım birimindeki erken doğmuş bir bebekte geç başlangıçlı Streptococcus pasteurianus sepsisi

Hatice DAĞI TÜRK, Nuriye TARAKÇI, Ayhan TAŞTEKİN, Ayşe Rüveyda UĞUR, İnci TUNCER