Çocukluk çağının selim akut miyoziti: 15 olgunun klinik ve laboratuvar bulguları

Amaç: Bu çalışmada, çocukluk çağının selim akut miyoziti tanısında önemli yeri olan ölçütleri gözden geçirmek amacıyla 15 çocukluk çağı selim akut miyoziti olgusuna ait klinik ve laboratuvar bulguları verilmiştir. Gereç ve Yöntem: Hastanemiz Çocuk Nöroloji Polikliniği’ne 15 Ocak-15 Mart 2011 tarihleri arasında yürüyememe nedeniyle yönlendirilen ve tipik çocukluk çağı selim akut miyoziti kliniği gösteren %80’i erkek ortalama 6,3 yaşında toplam 15 olgu çalışmaya alındı. En sık ön tanı Guillain Barré sendromu (%47) idi. Bulgular: Prodrom süresi 2-10 gün olup, sık görülen bulgular boğaz ağrısı, ateş ve öksürüktü. Kliniğe başvurdukları sırada iki taraflı baldır ağrısı ve yürüyememe yakınması olan olgularımızda, üç gün içinde klinik bulgularda hızlı ve kendiliğinden düzelme gözlendi. Olguların %87’sinde lökopeni, %47’sinde trombositopeni, %87’sinde hafif alanin aminotransferaz yüksekliği saptandı. Serum CPK değerleri 580-8250 (ortalama 2970±2190) U/L arasında değişmekteydi ve bir hafta içinde normal sınırlara geriledi. Çıkarımlar: Çocukluk çağının selim akut miyoziti klinik ve laboratuvar bulgularıyla gelen olgularda tanının erken düşünülmesi, gereksiz tetkik ve farklı tedavi seçeneklerini önlemek açısından önemlidir.

Benign childhood acute myositis: clinical and laboratory findings of 15 cases

Aim: In this study; clinical and laboratory findings of 15 cases with benign childhood acute myositis are presented to look over pathognomonic findings of the disease. Material and Method: Fifteen typical cases with benign childhood acute myositis referred to our Pediatric Neurology Clinic because of inability to walk, from 15th of January to 15th of March 2011, were enrolled into this study. Eighty percent of cases were male and their mean age was 6.3 years. Guillian-Barre’s syndrome was the most common initial diagnosis (47% of the cases). Results: Prodromal period lasted 2- 10 days and common symptoms were sore throat, fever and cough. When they were referred to our clinic, the patients complained of pain in both calves and inability to walk. In three days period; the symptoms resolved fast and spontaneously. Leucopenia at 87%, thrombocytopenia at 47%, mildly high alanine transaminase at 87% of the patients were detected. Serum creatinin kinase level ranged from 580 to 8250 U/L and it regressed to normal level within one week. Conclusions: In the patients of whom clinical and laboratory findings are suggestive of benign childhood acute myositis, it is important to think early diagnosis, which prevents unnecessary laboratory evaluations and therapeutic approaches.

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