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Ortalama Platelet Hacmi (MPV), Platelet Dağılım Genişliği (PDW), Nötrofil/Lenfosit Oranı (NLR), Red Cell Dağılım Genişliği (RDW), ve Platelet/Lenfosit Oranının (PLR) Fetal Distresi Öngörmedeki Yeri

Amaç: Çalışmamızın amacı fetal distres nedeniyle sezaryen ile doğum yapan term tekil sağlıklı gebelerin doğum öncesi bakılan kan parametrelerinin spontan vajinal doğum yapan term tekil sağlıklı gebeler ile farklı olup olmadığı ve akut fetal distresi öngörmedeki yerini araştırmaktır. Gereç ve Yöntem: Çalışmaya term tekil gebeliği ve herhangi bir hastalığı olmayan, latent fazda spontan doğum eylemi başlaması nedeniyle doğum salonuna yatırılan ve travay takiplerinde Kategori III fetal kalp atım trasesi (fetal distres) gelişen 124 gebe dahil edildi. Kontrol grubu olarak spontan vajinal doğum gerçekleştirilen 126 sağlıklı term gebe çalışmaya alındı. Tam kan parametreleri, yaşı, obstetrik öyküsü, gebelik haftası, oksitosin uygulanıp uygulanmadığı, doğum şekli, doğum kilosu, yenidoğan cinsiyeti, maternal komplikasyonlar, APGAR skoru (1. ve 5. dk), yenidoğan yoğun bakım ünitesine yatış olup olmadığı incelendi. Bulgular: Fetal distres gelişen olguların kontrol grubuna göre gravida, parite, yaşayan çocuk sayısı daha az, erkek yenidoğan sayısı anlamlı yüksek saptandı. Ayrıca 1. ve 5. dk APGAR skorları kontrol grubundan daha düşük olmasına rağmen Yenidoğan Yoğun Bakım Ünitesi'ne (YYBÜ) yatış oranı farklılık göstermedi. Kontrol grubuna oranla Hematokrit (Hct), Lenfosit sayısı, ve Ortalama Platelet Hacmi (MPV) daha düşük, nötrofil sayısı, platelet dağılım genişliği (PDW), nötrofil/lenfosit oranı (NLR) ve platelet/lenfosit oranı (PLR) daha yüksek saptandı. Sonuç: Eylem öncesi bakılan tam kan sayımında MPV düşüklüğü, PDW, NLR, PLR yüksekliği saptanan gebeler daha yakın takip edilmeli ve bu olgularda intrapartum akut fetal distres gelişebileceği akılda tutulmalıdır.
Anahtar Kelimeler:

Mean platelet volume (MPV), platelet dağılım genişliği (PDW), nötrofil/lenfosit oranı (NLR), red cell dağılım genişliği (RDW), platelet/lenfosit oranı (PLR), akut fetal distres

The role of Mean platelet volume (MPV), Platelet Distribution Width (PDW), Neutrophil‑to‑lymphocyte ratio (NLR), Red Cell Distribution Width (RDW), and Platelet-to- lymphocyte ratio (PLR) in predicting acute fetal distress

Aim: Our study aimed to compare complete blood count parameters between term single healthy pregnant women who had cesarean section due to fetal distress and who had a spontaneous vaginal delivery and investigate the importance of these variables in predicting acute fetal distress. Material and Method: The study included 124 term nullipara pregnant women who were admitted to the delivery room due to the onset of spontaneous labour in the latent phase and who developed Category III fetal heart rate trace (fetal distress) during labour follow-up. As the control group, 126 healthy nullipara women who had spontaneous vaginal delivery were included in the study. In addition, blood parameters, age, obstetric history, gestational week, oxytocin administration status, mode of delivery, birth weight, newborn gender, maternal complications, the APGAR score, neonatal intensive care unit admission status were examined. Results: The cases with fetal distress were found to have lower gravida, parity, less alive children, and a significantly higher number of male newborns than the control group. In addition, although the APGAR scores at the 1st and 5th minutes in the fetal distress group were lower than the control group, the NICU admission rate was not significantly different. HCT, lymphocyte count, and MPV were lower, neutrophil count, PDW, NLR, and PLR were higher in the fetal distress group compared to the control group. Conclusion: Pregnant women with low MPV, PDW, NLR, and high PLR in complete blood count before the labour should be followed up closely, and it should be kept in mind that intrapartum acute fetal distress might develop.
Keywords:

Mean platelet volume (MPV), Platelet Distribution Width (PDW), Neutrophil‑to‑lymphocyte ratio (NLR), Red Cell Distribution Width (RDW), ve Platelet-to- lymphocyte ratio (PLR), fetal distress,

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Türk Kadın Sağlığı ve Neonatoloji Dergisi-Cover
  • Başlangıç: 2019
  • Yayıncı: Sağlık Bilimleri Üniversitesi Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi
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