Şeval ÇİÇEK, Zeynep AKDEMİR, Selin ÇELİK, Seza KURUKAFA, İlknur ÖZKAYA, İpek YILMAZ, Yusuf Aytaç TOHMA, Hulusi ZEYNELOGLU

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Koronavirus Hastalığı 19 ve İnfertilite

Pnömoniye sebep olan ciddi akut solunum yolu sendromu koronavirus 2 (SARS-CoV-2) ilk olarak 2019 yılının Aralık ayındaÇin’in Wuhan şehrinde saptanmıştır. Enfeksiyonun nedeni koronavirus ailesinden SARS-CoV-2 virüsüdür ve ilk kez 2019yılında keşfedildiği için koro-navirus hastalığı 19 yani COVID-19 olarak isimledirilmiştir. Virüsün hücreyle etkileşmek içinkullandığı reseptörler tip I ve tip II alveolar epitel hücreleri, ince bağırsaktaki enterositler, kalp, böbrekler ve testisler gibipek çok organ sisteminde ifadelenmektedir. Bu nedenle COVID-19 birden fazla sistemi etkilemektedir. Biz bu derlememizdeCOVID-19 ve infertilite ilişkisini gözden geçirdik. Hem virüsün kendisinin hem de pandemi sürecinin infertiliteye etkisiüzerinde durulmuştur. COVID-19’un; erkek ve kadın üreme sistemi üzerine etkilerine, tedavide kullanılan ilaçların infertiliteile ilişkisine, endometriosis ve polikistik over sendromu (PCOS) gibi özel durumlarla olan ilişkisine, pandemi dönemindetüp bebek (IVF) laboratuvarlarının durumuna ve halihazırda devam eden infertilite tedavilerinin akıbetine, psikolojikboyutuna ve infertilite hastalarının psikolojik durumu üzerindeki etkisine değinilmiştir. Hastalığın daha yeni olması veyapılan çalışmaların kısıtlılığı bilgilerimizi sınırlandırmaktadır. Kesin kanıtlanmış verilerin bulunmaması ve çalışmalarınuzun dönem sonuçlarının bilinmemesi karşılaşılan en önemli zorluklardır. Bu nedenle bu konu ile ilgili olan bilgilerimizinartması için daha fazla çalışma yapılması gerekmektedir
Anahtar Kelimeler:

Ciddi akut solunum yolu sendromu koronavirus 2, COVID-19, erkek infertilitesi, kadın infertilitesi, gebelik

Coronavirus Disease 19 and Infertility

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes pneumonia, was first detected in Wuhan,China in December 2019. The cause of the infection is the SARS-CoV-2 virus from the coronavirus family, and since it wasfirst discovered in 2019, it was named as coronavirus disease 19 (COVID-19). The receptors used by the virus to interactwith the cell are expressed in many organ systems such as type I and type II alveolar epitheli-al cells, enterocytes inthe small intestine, heart, kidneys and testicles. Therefore, COVID-19 affects more than one system. In this review, wereviewed the relationship between COVID-19 and infertility. The effect of both the virus itself and the pandemic processon infertility has been emphasized. COVID-19; the effects on the male and female reproductive system, the relationshipbetween drugs used in treatment with infertility, their relationship with special conditions such as endometriosis andpolycystic ovary syndrome (PCOS), the status of in vitro fertilization (IVF) laboratories during the pandemic period, andthe outcome of the on-going infertility treatments, its psychological dimension and its effect on the psychological statusof infertility patients are mentioned. The fact that the disease is newer and the limited number of studies are limitingour knowledge. Lack of proven data and long-term results of the studies are the most important difficulties encountered.Therefore, more studies are needed to increase our knowledge on this subject.
Keywords:

Severe acute respiratory syndrome coronavirus 2, COVID-19, Male Infertility, Female Infertility, pregnancy,

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Türk Kadın Sağlığı ve Neonatoloji Dergisi-Cover
  • Başlangıç: 2019
  • Yayıncı: Sağlık Bilimleri Üniversitesi Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi
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