Berna AKINCI ÖZYÜREK, Derya YENIBERTIZ, Mehmet Sinan AYDIN

Akciğer kanseri olan hastalarda deliryum prediktörleri nelerdir?

Amaç: Deliryum, ilerlemiş kanserde yaygın bir psikiyatrik bozukluktur ancak akciğer kanseri olan hastalarda deliryum hakkında çok az sayıda çalışma mevcuttur. Bu çalışmada, akciğer kanseri olan hastalarda gelişen deliryum prediktörlerinin, cerrahiden bağımsız olarak araştırılması amaçlanmıştır. Yöntem: Bu çalışmada, 2013-2019 yılları arasında 18 yaş üstü, akciğer kanseri tanısı alan ve herhangi bir sebeple hastaneye yatışı sırasında deliryum tanısı konulan ve aynı dönemlerde benzer sayıda 18 yaş üstü olup akciğer kanseri olan ancak deliryum tanısı olmayan toplam 212 hasta retrospektif olarak incelenmiştir. Hastaların deliryum tanısı yatışları sırasında psikiyatri konsültasyonu ile Ruhsal Bozuklukların Teşhis ve İstatistik El Kitabı V. Kriterlerine göre konulmuştur. Hastaların yaş, cinsiyet, hastanede kalış süresi, komorbiditeleri, tanı anındaki laboratuar parametreleri (hemogram, biyokimya), akciğer kanseri tipi ve mevcut organ metastazları hasta dosyalarından ve hastane bilgi sisteminden kaydedilmiştir. Hastaların nötrofil / lenfosit oranı (NLR) ve platelet / lenfosit oranları (PLR) hesaplanmış ve kaydedilmiştir. Hastalar, deliryum tanısı alan ve deliryum tanısı almayan akciğer kanseri tanısı olan hastalar olarak iki gruba ayrılarak karşılaştırılmıştır. Bulgular: Çalışmamızda 212 hastanın %93,9’u erkek ve yaş ortalaması 63,4 ± 8,7 (38-91) yıldır. Deliryum tanılı hasta sayısı 126 olup deliryumu olmayan hastaların tanı yaşı medyan 64,0 (59,0-71,0) olarak belirlenmiştir. Deliryum olan grupta ortalama beyaz kan hücresi (WBC), nötrofil, nötrofil/lenfosit oranı (NLR) ve trombosit/lenfosit oranı (PLR) seviyeleri daha yüksek olmasına rağmen ortalama lenfosit düzeyi daha düşük bulunmuştur (p

What are the predictors of delirium for patients with lung cancer?

Objective: Delirium is a common psychiatric disorder in advanced cancer but there are a few reports about delirium in patients with lung cancer. We aimed to investigate the predictors of delirium occurring in patients with lung cancer regardless of surgery. Methods: A total of 212 patients over the age of 18 hospitalized with lung cancer for any reason between 2013-2019 were retrospectively investigated in this research. Patients diagnosed with delirium between these dates were determined and patients with concurrent lung cancer diagnosis were selected for this study. A similar number of patients over the age of 18 diagnosed with lung cancer but not diagnosed with delirium in the same period were also defined as the control group. Patients were diagnosed with delirium by the criterias of the Diagnostic and Statistical Manual of Mental Disorders V. criterias during their hospitalization by psychiatrist consultant physician. Age, gender, comorbidities, durations of hospital stay, laboratory parameters at the time of diagnosis (biochemistry, hemogram), the type of lung cancer and existing organ metastases of the patients were recorded from the patient files and hospital information system. Neutrophil to lymphocyte ratio and paletelet to lymphocyte ratio were calculated and recorded. The patients with lung cancer were dividedinto two groups as patients diagnosed with delirium and without delirium and they were compared. Results: Of the 212 patients, 93.9% of the were male and the average age of the patients was 63.45 ± 8.68 (38- 91) years in our study. The number of the patients with delirium was 126 and the median diagnostic age of the patients with delirium was determined to be 64.00 (59.00- 71.00) years. Although the median levels of white blood cell (WBC), neutrophil, neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) were higher, the median level of lymphocyte was found to be lower in the group with delirium (p

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