Ümit AYDOĞMUŞ, Serkan DEĞİRMENCİOĞLU, Erhan UĞURLU, Gökhan YUNCU, Figen TÜRK

Pnömonektomi sonrası maligniteden ilişkisiz uzun dönemde solunum olayları için risk faktörleri

Amaç: Bu çalışmada pnömonektomi sonrası geç başlangıçlı maligniteden bağımsız solunum olayları değerlendirildi. Çalışma planı: Ocak 2009 - Eylül 2014 tarihleri arasında kliniğimizde pnömonektomi geçirmiş 78 hastanın (73 erkek, 5 kadın; ort. yaş 55.6±9.6 yıl; dağılım 32-79 yıl) tıbbi verileri retrospektif olarak incelendi. Ameliyat öncesinde sigara içme alışkanlıkları, eşlik eden hastalıklar, Amerikan Anesteziyoloji Derneği risk skoru, EuroSCORE, neoadjuvan kemoterapi ihtiyacı, kanser hücre tipi ve klinik evre kaydedildi. Ameliyat sonrasında komplikasyonlar ve uygulanan tedavi yöntemlerine ilişkin veriler kaydedildi. Bulgular: Ortalama takip süresi 35.2±22.0 ay (dağılım 9-104 ay) idi. Hastaların 21’inde (%35.0) lokal nüks ve ikinci primer akciğer tümörü gibi malignite ile ilişkili solunum olayı gelişti. Malignite ile ilişkisiz solunum olayları 18 hastada (%31.6) görüldü. Amerikan Anesteziyoloji Derneği skoru yüksek olan (p=0.01), ameliyat öncesi birinci saniyedeki zorlu ekspiratuvar volüm

Risk factors for malignancy-unrelated long-term respiratory events after pneumonectomy

Background: In this study, we aimed to evaluate late-onset, malignancy-unrelated respiratory events following pneumonectomy.Methods: The medical data of 78 patients (73 males, 5 females; mean age 55.6±9.6 years; range, 32 to 79 years) who underwent pneumonectomy in our clinic between January 2009 and September 2014 were retrospectively analyzed. Preoperatively, data including smoking habits, comorbidities, the American Society of Anesthesiologists risk score, the EuroSCORE, neoadjuvant chemotherapy need, cancer cell type, and clinical stage were recorded. Postoperatively, data included complications and treatment modalities were recorded.Results: The mean follow-up was 35.2±22.0 months (range 9 to 104 months). Malignancy-related respiratory events such as local relapse and a second primary lung tumor developed in 21 patients (35.0%). Non-malignancy-related respiratory events were seen in 18 patients (31.6%). Long-term, non-malignancy-related morbidity was more prevalent in the patients with high American Society of Anesthesiologists scores (p=0.01), preoperative forced expiratory volume in one second

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